Revalgine

Revalgine is a combined spasmoanalgesic from the Indian pharmaceutical company Shreya.

The drug consists of several active substances: metamizole (analgin), pituopenone, relieving muscle spasm, and fenpiverinia, relaxing smooth muscle. The active components of the drug potentiate each other, increasing the effect of the action of Revalgine.

Basically, the drug in the form of a solution or tablets is administered to patients who have pain syndrome accompanied by spasms of the smooth muscle of the internal organs.

Clinical and pharmacological group

Spasmoanalgesic.

Terms of sale from pharmacies

You can buy without a doctor's prescription.

Price

How much does Revalgine cost in pharmacies? The average price is at the level of350 rubles.

Composition and form of release

The drug Revalgin is produced in two dosage forms:

Solution for injection: from colorless to pale yellow, transparent (1, 2 or 5 ml in ampoules, in polyethylene pallets of 3, 5 or 10 ampoules, in a cardboard bundle 1-5 pallets);

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Tablets: white, round, flat, have cut edges and a separation groove (in 10 or 20 strips, in a cardboard bundle 1-5 or 10 strips).

Active ingredients in 1 ml of solution for injection:

Bromide fenpiverinia - 0.02 mg;
Pitophenone hydrochloride - 2 mg;
Metamizole sodium - 500 mg.

Additional components: edetate disodium, sodium metabisulphite, potassium dihydrogen phosphate, sodium hydroxide, water for injection.

Active ingredients in 1 tablet:

Bromide fenpiverinia - 0.1 mg;
Pitophenone hydrochloride - 5 mg;
Metamizole - 500 mg.

Additional components: colloidal silicon dioxide, talc, starch, microcrystalline cellulose, lactose, magnesium stearate.

pharmachologic effect

The action of Revalgine is based on the properties of its active components. It includes spasmolytic agent of pituopenone hydrochloride, non-narcotic analgesic methamizole sodium, and antifungal agent fenpiverinia bromide.

Metamizole is a derivative of pyrazolone. It has antipyretic, anti-inflammatory and analgesic effects. Fenpiverinium and pituopenon, thanks to anticholinergic and myotropic action, relax smooth muscle.

The combination of these components contributes to the mutual enhancement of their effect on the body, which is expressed in relaxation of smooth muscles, alleviating pain and reducing body temperature.

Indications for use

What helps? Indications for Revalgine are the following ailments:

Pain syndrome after surgical interventions and diagnostic procedures - as an auxiliary.
Headache and migraine pain (for tablets), pain in the joints, myalgia, ischialgia, neuralgia - for short-term symptomatic therapy.
Pain syndrome, mild or moderate, with spasms of smooth muscles of internal organs - dysmenorrhea, spasms of the intestine, biliary and renal colic, and other spastic conditions of internal organs.

Also, Revalgine solution is indicated for dyskinesia of bile ducts and algodismenore. The drug in the form of tablets is additionally used for catarrhal diseases and infectious inflammatory processes for lowering body temperature.

Contraindications

Absolute:

megacolon;
collapse;
acute porphyria;
chronic heart failure in decompensation stage (for solution for injection);
stable and unstable angina (for solution for injection);
pregnancy (I trimester and the last 6 weeks);
lactation period (breastfeeding);
severe liver dysfunction;
severe renal dysfunction;
genetic deficiency of glucose-6-phosphate dehydrogenase;
tachyarrhythmia;
angle-closure glaucoma;
hyperplasia of the prostate (with clinical manifestations);
oppression of bone marrow hematopoiesis;
intestinal obstruction;
hypersensitivity to pyrazolone derivatives and other components of the drug.

Tablets are not prescribed for children under 5 years.

Solution for injection is not prescribed for children under 3 months of age or at a body weight of less than 5 kg.

Intended use for pregnancy and lactation

The drug is contraindicated for admission in the first trimester of pregnancy and 6 weeks before childbirth. In the rest of the period - use as agreed with the doctor.

During the period of breastfeeding, the drug is also contraindicated. If it is necessary to apply the drug, breastfeeding is temporarily stopped and restored 48 hours after taking Revalgine.

Dosage and route of administration

As indicated in the instructions for use, adults and adolescents over 15 years of age are prescribed Revalgin inside (preferably after eating) 1-2 tablets 2-3 times / day. The daily dose should not exceed 6 tab. Duration of reception no more than 5 days.

An increase in the daily dose of the drug or the duration of treatment is possible only under the supervision of a physician.

In children, the drug is used only as directed by a doctor. Dosage for children 6-8 years -1/2 tablets; for children 9-12 years old - 3/4 tablets; for children 13-15 years - 1 tablet; multiplicity of appointment - 2-3 times / day.

Other dosage regimens are possible only after consultation with a physician.

Injection

The drug is administered intravenously (IV) or intramuscularly (IM).

Adolescents after 15 years and adults with acute severe colic develop a solution intravenously slowly in a dose of 2 ml (at a rate of 1 ml per minute). With intravenous slow infusion, it is usually sufficient to administer one 2 ml of Revalgine, but if necessary, the injection can be repeated after 6-8 hours.

Intramuscularly the drug is administered 2 times a day for 2 ml, with a maximum daily dose of 4 ml. The course of therapy - no longer than 5 days.

Recommended single dose of solution for children, depending on age and body weight:

3-11 months (weight 5-8 kg): in / m - 0.1-0.2 ml;
1-2 years (weight 9-15 kg): in / m - 0.2-0.3 ml, in / in - 0.1-0.2 ml;
3-4 years (weight 16-23 kg): in / m - , -, ml, in / in - , -, ml;
5-7 years (weight 24-30 kg): in / m - , -, ml, in / in - , -, ml;
8-12 years (weight 31-45 kg): in / m - , -, ml, in / in - , -, ml;
12-15 years: in / m / in / in - , -1 ml.

If necessary, a repeated injection of the drug (in similar doses) may be prescribed.

The solution is incompatible with other drugs in the same syringe.

Before using the ampoule with Revalgin it is required to warm in the hand.

Side effect

The medicine is usually well tolerated by patients. The use of the drug Revalgin in rare cases can cause the following side effects:

Decrease in sweating, difficulty urinating, paresis of accommodation.
Dizziness, tachycardia, headache, decreased blood pressure, cyanosis.
A burning sensation in the epigastric region, dry mouth.
Allergic reactions (anaphylactic shock, pruritus, urticaria, rash), angioedema.

With long-term treatment with Revalgine or with its administration in high doses, there may be impaired functionality of the kidneys or hematopoiesis system.

Overdose

An overdose with the drug gives the following symptoms:

nausea;
vomiting;
convulsive twitchings;
pain in the stomach;
confusion of consciousness;
drowsiness;
a sharp drop in blood pressure.

Emergency assistance should be aimed at eliminating symptoms - washing the stomach with a weak solution of baking soda and taking a shock dose of enterosorbents (activated carbon, Enterosgel).

special instructions

Sometimes metamizole metabolites can stain urine red.

With prolonged (more than a week) application, it is necessary to monitor the picture of peripheral blood and indicators of the functional state of the liver.

With caution and under the supervision of a doctor, the drug should be administered to patients with impaired liver and / or kidney function, with a tendency to hypotension, bronchospasm, as well as with increased individual sensitivity to NSAIDs or non-narcotic analgesics.

Interaction with other drugs

When using the drug, it is necessary to take into account the interaction with other drugs:

Simultaneous use with cyclosporine reduces the level of the latter in the blood.
Sedatives and tranquilizers increase the analgesic effect of Revalgine.
The simultaneous use of revalgine with other non-narcotic analgesics may lead to a mutual enhancement of toxic effects.
Barbiturates, phenylbutazone and other inducers of microsomal liver enzymes weaken the action of metamizole.
Tricyclic antidepressants, oral contraceptives, allopurinol disrupt metamizole metabolism in the liver and increase its toxicity.
If you need to use these and other medications at the same time, you should consult your doctor.

Reviews

We offer you to get acquainted with the opinions of people who used the drug Revalgin:

Elena. To me revalgin it approaches, quickly helps or assists, for a long time suffices also pobochki at me is not present. I've been buying it for 2-3 years already, it's from everything, from pain, from heat, from spasms. A good tool at an affordable price.
Irina. Means inexpensive, but it did not help me. I do not like to use tablets at all, but the girls will understand me, tolerating the monthly pain is unbearable. Previously, always endured until she married and my husband did not persuade me to drink a pill. Has drunk revalgin. After 2 hours I realized that the pain does not go away, I drank the second. Also nothing, I thought, I was in vain to persecute myself. At the next cycle, they bought other painkillers and this time within 20 minutes the pain subsided. From revalgin, in the end, refused.
Natalia. Headaches began to appear to me from time to time. I understand that it is already necessary to see a doctor, but I always pull to the last. I used to take analgin, but I heard somewhere that it is harmful to health. The pharmacy advised to buy this drug. What can I say, the pain takes off with a bang. Literally in a matter of minutes, but noticed that if you take Revalgin on an empty stomach, nausea appears. Although, maybe this is just my reaction. Definitely recommend, other pobachek not observed.