Medifox - a drug for the treatment of pediculosis and scabies

Medifox from lice is an insecticidal drug that is used in the treatment of lice, carpels and mange.

To date, this tool has earned a high reputation when using it in special detention centers and shelters for the sanitary treatment of people heavily infected with lice, which indicates its high effectiveness.

The active substance is permethrin, which acts on the peripheral nerve endings of lice and paralyzes them. Parasites die from circulatory arrest. The component refers to natural strong insecticides, which are obtained from plants of the Astra family (chrysanthemums, damask chamomile, etc.).

Clinical and pharmacological group

Permethrin, the active substance of the drug, is an antiparasitic component.

Conditions of leave from pharmacies

Available without a prescription.

Price list

How much is MediFox? The average price in pharmacies is at the level of160 rubles.

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Form of issue and composition

"MediFox" is produced in the following forms:

• concentrate 5%;
• super concentrate 20%;
• gel.

Concentrate is a colorless liquid with a yellowish tinge. The gel is a gelatinous mass of white color.

5% concentrate of the drug is used to get rid of lice and scabies and is intended for home use. The product can be purchased at the pharmacy.

"MediFox" 20% is used by services that specialize in the destruction of cockroaches, ants, fleas, flies. The drug is used to treat objects that have come into contact with insects. This variety of "MediFox" is also suitable for the treatment of scabies and lice.

In the form of a gel, "MediFox" is used to eliminate lice. The drug is suitable for home use for both children and adults.

• "MediFox" 5% is sold in ampoules (2 ml each) and bottles of 24 ml, l and 1 l.
• A drug with a 20% concentration is sold in ampoules and 10 ml vials;, l, 5 l;, l; 1 liter and 5 liters.
• The gel can be purchased in a 50 ml tube.

The active substance of the drug is permethrin, which is characterized by powerful antiparasitic activity. This substance is obtained from the inflorescences of Dalmatian chamomile. Permethrin has a neuro-paralytic effect on insects, as it affects their nerve endings. As a result, lice are paralyzed and die.

Pharmacological effect

MediFox is an antiparasitic agent. It breaks the permeability for cations of membranes of nerve cells of insects. The use of MediFox is effective for sexually mature individuals of genital and pubic lice, nits and scabies.

When applied to the skin, it practically has no toxic effect on humans and warm-blooded animals. According to the reviews, MediFox in recommended dosages does not have a local irritant, skin-resorptive and sensitizing effect.

Indications for use

Gel and 5% concentrate have similar indications for use, concentrate 20% - others (processing in diluted form of premises, bed linen, clothes, scalp and skin). The first group of indications are:

• the destruction of clothing lice;
• treatment of scabies, head and pubic lice (the presence of lice), nitrate;
• If the ants are in the apartment, the drug will help get rid of them;
• disinsection of premises, things and laundry for the destruction of ticks scabies, nits, bedbugs, rat ticks, flies, cockroaches;
• treatment of linen and objects for the prevention of infection with pediculosis while being in the outbreaks of the above-mentioned parasites.

Contraindications

Treatment with this medication is prohibited:

1. During lactation and pregnancy;
2. When dermatological diseases occur in acute form, if their manifestations are localized on the areas of skin affected by parasites;
3. With increased sensitivity to chrysanthemums.

Also, a contraindication to the use of MediFox is intolerance to permethrin, pyrethroids or any auxiliary component that is part of the drug.

In the form of a gel, the drug is contraindicated for children under 6 months, the emulsion is prescribed after the child reaches a year old. All other dosage forms are contraindicated for children under 5 years.

Use in pregnancy and lactation

According to FDA studies, this drug belongs to category B. This means that the studies were conducted exclusively on animals and they did not reveal the risk of adverse effects on the fetus.

But pregnant women did not conduct proper studies. Therefore, the use of the drug in the period of gestation is possible only if the benefit to the mother exceeds the risk to the fetus.

Dosage and route of administration

The instructions for use indicate that Medifox from lice and scabies are applied externally, in the form of a freshly prepared aqueous emulsion.

Recommended dosing regimen:

• Head and pubic pediculosis% aqueous emulsion (to 8 ml of concentrate (4 ampoules of 2 ml or 1/3 of the contents of a 24 ml bottle) add 200 ml of boiled warm water). Prepared emulsion should be applied abundantly to the hairy parts of the body (with fthiracy) or wet hair of the head, slightly rubbed into the skin with a cotton swab. MediFox should be rinsed in 20 minutes by running warm water using soap (shampoo).
• Scabies% aqueous emulsion (to 8 ml of concentrate (4 ampoules of 2 ml or 1/3 of the contents of a 24 ml bottle) add 100 ml of boiled warm water). Prepared emulsion once a day (at night) should be carefully rubbed into the skin (first treated upper limbs, then the trunk and lower limbs). Treatment is not subject to the skin of the neck and face, as well as the scalp. The duration of the course is 3 days (24 ml of the drug). On the fourth day after the end of therapy, you must take a shower and change your underwear and bed linen.

Side effects

Side-effects are:

• rash;
• swelling;
• burning of skin in the place of application;
• paresthesia;
• increased itching;
• erythematous rashes.

In case of contact with the mucous membrane, rinse immediately with water and seek medical advice.

Overdose

Overdose by the drug under consideration is unlikely. This is due to its low systemic absorption. If the drug accidentally got inside, then it is required to carry out measures to cleanse the stomach. Symptomatic therapy is also indicated.

special instructions

Before you start using the drug, read the special instructions:

1. The emergence of hypersensitivity reactions requires discontinuation of treatment.
2. It is recommended that medical personnel wear rubber gloves. After the procedure, wash hands thoroughly with soap and water. Procedures should be carried out in a well-ventilated area.
3. Avoid contact with the eyes, nose, mouth, external genitalia (if this happens - the mucous membranes are washed abundantly with running water).
4. If itching continues for more than 4 weeks after scabies treatment, a doctor's consultation is mandatory.
5. With the simultaneous administration of other drugs or the presence of concomitant skin diseases of the scalp, a compulsory medical consultation is required before the treatment begins.

Drug Interactions

It is not recommended to use the drug in conjunction with other cutaneous medicines.

Reviews

We picked up some reviews of people taking Medifox:

1. Oksana. From the children's camp, my daughter returned with these parasites. There was not much choice in the single pharmacy of our small town, we had to take that drug that was available. However, the remedy turned out to be effective - in order to get rid of the problem there was only one treatment for the entire family. Any unpleasant sensations or an unpleasant smell at use have not noticed.
2. Anna. MediFox processed both of its children, who brought lice from the garden. The senior man of courage sat for 20 minutes, and the younger one had an allergy and itching, it was necessary to rinse immediately. As a result, the son of a louse disappeared, the drug acted. But my daughter had to look for a more delicate remedy.
3. Tatyana. The daughter was infected in the kindergarten, and complaining began when parasites became very numerous. Recommended medifoks. After treatment, then long dead lice and nits comb out, because the hair is not only long and thick, but also curly. In our case, this remedy has helped with the first application - during the week only a few nits found after treatment were succeeded and all.

The vast majority of reviews about MediFox for treating lice are positive, which is due to the high efficacy of the remedy. So, in the reviews it is noted that if the instruction is strictly followed, the remedy destroys lice for one application. An additional advantage people consider the low cost of the drug.

However, high efficiency and relatively low price do not make MediFox an ideal tool, since, unfortunately, in many reviews it is indicated that the drug causes unpleasant sensations during use, and is also capable of provoking a strong allergic reaction. Unpleasant sensations include burning, itching, tingling and tingling of the scalp on which the product was applied.

Analogues

Structural analogs for the active substance:

• Nyx;
• Nittifor;
• NOCs.

Analogues for the pharmacological group (antiparasitic agents):

• Anti-bit;
• Benzyl benzoate;
• Benzyl benzoate ointment;
• Bubil;
• Itas;
• Sodium thiosulfate;
• Nittifor;
• Nyuda means a pediculicide;
• Couple plus;
• Pediculum Ultra;
• Solantra;
• Spregal;
• Circassian water;
• Yurax.

Before using analogues, consult your doctor.

Storage conditions and shelf life

Store at a temperature not exceeding 25 ° C, in a place protected from light and moisture, inaccessible to children.

Shelf life - 5 years.

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