What helps Cardiket: instructions for use

Kardiket is an antianginal drug that is used to prevent attacks of angina with prolonged therapy of coronary heart disease.

The use of this drug helps to reduce the need for oxygen in the myocardium, reducing post-and preload. The action of the drug can reduce the flow of blood to the atrium, which reduces pressure in a small circle and reduces the manifestation of undesirable symptoms in lung edema.

On this page you will find all information about Carditis: the full instruction on the application for this medicine medium, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already applied Cardiac. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Peripheral vasodilator. Antianginal drug.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much does the Cardicoot cost? The average price in pharmacies is at the level of60 rubles.

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Form of issue and composition

Round white tablets with a long curative effect. On one side is a flat section with IR indication above the risk and figures "20, 40 or 60" below the risks that denote the amount of isobiode dinitrate in milligrams. The other side is convex, with the designation of the manufacturing company SCHWARZ PHARMA.

The composition of 1 tablet includes:

• Active substance: isosorbide dinitrate - 20, 40 or 60 mg;
• Auxiliary components: lactose monohydrate, talc, magnesium stearate, potato starch, polyvinyl acetate.

In the package of cardboard place 2 or 4 blisters with cells for 10 tablets. Hard gelatin capsules with long-lasting therapeutic effect of dark beige color, filled with white and yellowish granules, which do not have a smell. Two blisters are placed in the package, 10 tablets in each.

Pharmacological effect

Antianginal drug, organic nitrate. Peripheral vasodilator with predominant effect on venous vessels. Stimulates the formation of nitric oxide (endothelial relaxing factor) in the vascular endothelium, causing activation of intracellular guanylate cyclase, the consequence of this is an increase in the level of cGMP, mediator vasodilation.

Promotes redistribution of coronary blood flow in the area with reduced blood supply. Increases tolerance to physical activity in patients with IHD, angina pectoris. It dilates the vessels of the brain, the dura mater, which can be accompanied by a headache. Like other nitrates, the drug develops cross-tolerance. After cancellation (interruption in treatment), the sensitivity to the drug is quickly restored.

Reduces the need for myocardium in oxygen by reducing preload and postload (reduces the final diastolic volume of the left ventricle and reduces the systolic tension of its walls). Possesses coronary dilatation. Reduces the flow of blood to the right atrium, helps reduce pressure in a small circle of blood circulation and regression of symptoms with pulmonary edema.

The onset of action after ingestion of the drug in the form of capsules retard - 15-40 minutes, maximum action - 8 hours, duration of action - 18 hours.

Indications for use

This medicine is recommended and indicated for the following cardiac disorders:

1. To arrest the condition after acute myocardial infarction,
2. Hypertension in a small circle of circulation of blood,
3. In order to prevent anginal attacks,
4. For the prevention of myocardial infarction (Cardiacet of prolonged action is applied),
5. Treatment of coronary heart disease for a long time to prevent attacks of angina pectoris,
6. With spasm of the coronary arteries (compulsory use of the cardiac catheter),
7. Spasms of peripheral arteries (eg, angiospastic retinitis or obliterating endarteritis),

It is also used as part of the integrated treatment of chronic heart failure (used in conjunction with cardiac glycosides, diuretics, inhibitors, etc.).

Contraindications

Contraindications to the use of the medicinal product are:

1. Hypovolemia;
2. Hemorrhagic stroke;
3. Children and adolescence under 18;
4. Pronounced arterial hypotension;
5. Severe aortic and / or mitral stenosis;
6. Craniocerebral injury;
7. Acute vascular insufficiency (vascular collapse, shock);
8. Simultaneous administration of inhibitors of phosphodiesterase type 5;
9. Acute myocardial infarction with severe arterial hypotension;
10. Closed-angle glaucoma with high intraocular pressure;
11. Hypersensitivity to the active ingredient or auxiliary components of the drug.

Relative contraindications Cardiabetes:

1. Severe anemia;
2. Toxic pulmonary edema;
3. Cardiac tamponade;
4. Hemorrhage in the brain;
5. Constrictive pericarditis;
6. Hypertrophic obstructive cardiomyopathy.

With caution and with careful medical supervision, the drug is prescribed for elderly patients, as well as in the following cases:

1. Hyperthyroidism;
2. Increased peristalsis of the gastrointestinal tract;
3. Malabsorption syndrome;
4. Pronounced hepatic insufficiency;
5. Severe renal failure;
6. Diseases accompanied by increased intracranial pressure;
7. Propensities to violations of blood circulation regulation due to low blood pressure (orthostatic disorders of blood circulation regulation).

Application in pregnancy and lactation

Pregnant and lactating mothers are given a cardic card only if the expected positive effects for the woman prevail over the potential risks to the fetus (child).

Instructions for use

In the instructions for use, it is stated that the Cardiquet is taken inside regardless of the meal, without chewing and squeezed with a small amount of liquid. In order to divide the tablet in half, it should be placed on a hard surface with a line of fracture upwards and press with your thumb on the tablet. It can easily be divided into two halves.

1. Tablets of prolonged action of 20 mg appoint 1 tab. 2 times / day. With increasing requirements for the drug, the dose can be increased to 1 tablet. 3 times / day.
2. Tablets of prolonged action of 40 mg at the beginning of treatment appoint 1 tab. 1 time / day or 1/2 tablet. 2 times / day. If the therapeutic effect is insufficient, the dose can be increased to 1 tab. 2 times / day. The second tablet should be taken no later than 8 hours after the first.
3. Tablets of prolonged action of 60 mg at the beginning of treatment appoint 1 tab. 1 time / day. If necessary, the dose can be increased to 1 tab. 2 times / day. The second tablet should be taken no later than 8 hours after the first.
4. The drug in the form of prolonged-action capsules is prescribed for 120 mg 1 time / day.

It is recommended to start treatment with the lowest doses and slowly increase the dose to the maximum effective dose. The decision on the duration of treatment is made by the doctor. The drug is intended for long-term use, and without consulting a physician, it should not be abruptly discontinued.

Side effects

In the reviews about Cardiacet there are reports that during the therapy with the drug there can be side reactions from the organs and body systems:

1. Gastrointestinal tract: nausea, dry mouth, vomiting, belching, epigastric pain.
2. Central nervous system: visual impairment, drowsiness, stiffness, slowing of psychophysical reactions, ischemic disturbances;
3. There may be allergic reactions in the form of skin rash, itching, hives, redness, exfoliative dermatitis.
4. Cardiovascular system: at the beginning of therapy, nitrate headaches may occur, which disappear after several days of regular medication administration. There may be more frequent heart rate, hypotension, orthostatic collapse, sensation of weakness, retardation, paradoxical bradycardia and angina pectoris, loss of consciousness against the background of loss palpitation;

It is also possible to develop addiction to the drug, which leads to a decrease in its therapeutic effectiveness.

Overdose

If too large doses of medication are administered to a patient, the symptoms of an overdose develop:

1. Loss of consciousness;
2. Nausea;
3. Tachycardia;
4. Dyspnea;
5. Development of paralysis and coma;
6. Disturbance of respiratory function;
7. Severe dizziness, development of collapse;
8. Cyanosis of the extremities and nasolabial triangle;
9. Diarrhea and indomitable vomiting, as a result of which the patient quickly develops violations of the water-salt balance.

At the first symptoms of an overdose, the patient must be rushed to the hospital. Treatment consists in washing the stomach and performing symptomatic therapy. There is no specific antidote.

special instructions

1. Cardiac can not be used to stop angina attacks.
2. The drug can affect the ability to drive vehicles, so during the period of treatment it is worth to abandon the potentially dangerous activities.
3. The action of the drug, violating the concentration of attention, significantly increases in parallel with the intake of alcohol, so alcohol should also be abandoned for the period of treatment.
4. When taking the drug in patients with primary lung diseases, a temporary hypoxemia, which is associated with a relative redistribution of blood flow to hypoventable alveolar zones. In patients with coronary heart disease, this can lead to transient myocardial ischemia.
5. With constant continuous therapy in high doses, the development of tolerance can develop, as well as the development of cross-tolerance to other drugs of the nitrate group.

Drug Interactions

1. Absorption of a cardiac from the stomach reduces enveloping and astringent drugs.
2. Simultaneous reception with acetylsalicylic acid improves circulation in the coronary vessels.
3. Increase in intraocular pressure is possible with a combination of cardiac with atropine or other M-holinoblokatorami.
4. In combination with dihydroergotamine, the hypotensive effect of the latter is enhanced by increasing its concentration in the blood. Reduction of the antianginal effect of the cardiac can occur when combined with sympathomimetics and alpha-blockers.
5. The most rational combination of cardiac therapy with nifedipine, propranolol, amiodarone is the combination in the therapy of coronary heart disease.
6. When co-administered with other vasodilators, blood pressure lowering agents, slow calcium channel blockers, neuroleptics, tricyclic antidepressants, ethanol, quinidine, adrenoblockers, inhibitors of the enzyme phosphodiesterase type 5, novocaineamide, drugs for the treatment of impotence hypotensive cardiovascular effect is potentiated.

Reviews

We picked up some of the people's opinions about the Kardiket drug:

1. Zhenya. A good drug, ama after a heart attack, take, the pain gradually pass (3-4dn, about the measure of getting used to the drug, it is necessary to endure), but the heart is good from it.
2. Fedor. I've been taking the cardiac since 1997, after the first heart attack. I take breaks in the reception so that I will not get used to it. From a headache I recommend validol with glucose. I first time and now after the breaks in cardiovascular reception I accept (I dissolve under the tongue) and there is no headache. The general advice: choose what is more important for you, so that there is no heart attack or light headache minutes 5. Good health to everyone. A person dies not because he is sick, but because he lives ...
3. Nikolai. At the end of the school, I was dragged into the polyclinic. After several checks on the uzi, the doctors told me that you have my sweet hypertension and you will not be taken into the army and you will not be able to work in metallurgical production. But I went against the system. And now you need to be responsible for your stubbornness. It's time to seriously think about the health of the heart, as it begins to mope. Doctors diagnosed that ischemic heart disease is just around the corner. And I read about Kardiket. Has drunk a course a month and other problems began a nausea, sometimes a vomiting. Prompt please, can be it carry to contraindications?

Analogues

The closest analogues are Cardiqet:

• Aerosonite;
• Dinisorb;
• Isacardin;
• From MacArthard;
• Is Mac Spray;
• Isoket;
• Isolong;
• Isosorbide dinitrate;
• Cardix;
• Nitrosorbide;
• TD spray Iso Mack.

Before using analogues, consult your doctor.

Storage conditions and shelf life

Keep out of reach of children at a temperature of no higher than 25 ° C. Shelf life - 5 years.

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