KURANTIL 25 and 75 tablets: instructions and opinions of people

Kurantil (active substance dipyridamole) is a drug that is effectively used to normalize the functions of the vascular system and the heart.

Has a retarding effect on the aggregation of platelets, enhances microcirculation. It presupposes a lifelong reception at cardiological and angiological problems of an organism. It is a powerful immunomodulator.

At the vascular level, the drug lowers the resistance of the coronary arteries, increases the number of bypass vessels, through which circulatory blood flow is carried out with simultaneous stimulation of collateral circulation, increases myocardial contractility, reduces overall peripheral vascular resistance, reduces arterial pressure, improves microcirculation and prevents blockage of arteries, prevents venous stasis of blood, reduces resistance of blood vessels of the brain, normalizes placental blood flow.

Clinical and pharmacological group

Antiaggregant. Immunomodulator.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much is the Kurantil? The average price in pharmacies is at the level of550 - 750 rubles.

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Form of issue and composition

The manufacturer "Berlin-Chemie" produces the drug in the following dosage forms:

• Curantil 25 - in the form of a dragee of 100 pieces in glass bottles number 1 in the box;
• Curantil H (N) 25 - in the form of tablets in a shell of 120 pieces in glass bottles number 1 in the box;
• Curantil H (N) 75 - in the form of tablets in a shell of 40 pieces per box.

According to the INN (international non-proprietary name), the active ingredient dipyridamole (dipyridamole) in all mass parts forms in the composition of all dosage forms of the drug Couantil.

Pharmacological effect

Dipiridamol - the main active substance of the drug, due to the action of this drug has antiaggregant (preventive thrombosis), immunomodulating and vasodilating (dilating vessels) act.

The appointment of Curantil promotes the expansion of the blood vessels of the heart, the increase in the speed and volume of blood flow, and the improvement of oxygen supply to the myocardium. Due to its ability to prevent the formation of thrombi, the drug is widely used in the treatment of a large number of cardiovascular diseases.

The use of Curantyl in pregnancy is due to the ability of this agent to prevent clogging of the blood vessels of the placenta, which makes it possible to avoid the development of various severe consequences associated with hypoxia (lack of oxygen) child.

The immunomodulatory effect of the drug is characterized by its ability to stimulate the synthesis of interferon and increase its activity. The drug is also widely used in the treatment and prevention of such viral diseases as influenza.

Indications for use

Treatment:

• Encephalopathy;
• Disturbances of microcirculation of any type (as part of complex therapy).

Prevention:

• Thromboembolism after surgery for prosthetic heart valves;
• Placental insufficiency in case of complicated pregnancy.

Treatment and prevention:

• Influenza and acute respiratory viral infections (for tablets at a dose of 25 mg, used as an immunomodulator and inducer of interferon);
• Violations of cerebral circulation by ischemic type.

Also, the drug is used in the following cases:

• Prevention of venous and arterial thrombosis and treatment of their complications;
• Primary and secondary prevention of coronary heart disease, especially with acetylsalicylic acid intolerance.

Contraindications

Curantil is strictly contraindicated in the presence of such diseases and conditions:

• subaortic stenosis of the aorta;
• common stenotic coronary artery atherosclerosis;
• severe heart rhythm disturbances;
• increased sensitivity to the components of Currantyl;
• acute myocardial infarction;
• Arterial hypotension (pressure below 90 mm Hg), collapse;
• unstable angina;
• Decompensated heart failure;
• hemorrhagic diathesis;
• diseases with a tendency to bleeding (ulcer of the stomach and duodenum).

Due to the lack of sufficient clinical experience in the use of curantyl in pediatrics, it is not recommended to prescribe it to children under 12 years of age.

Use in pregnancy and lactation

"Kurantil" is one of the most frequently prescribed drugs during pregnancy. It is prescribed by an observing gynecologist or obstetrician for the normalization of the fetal condition for various abnormalities in the functioning of the child's place (placenta). The placenta consists of a huge number of small blood vessels and capillaries, through which nutrients are transported. Vitamins and oxygen to the fetus.

When failures occur in the circulatory system, the fetus loses useful elements and molecules of oxygen, which can affect its growth and development. The drug of choice for the normalization of the placenta is "Kurantil" (as the safest and most effective drug).

The use of the drug during lactation is possible only if the expected benefit of the treatment exceeds the possible risk.

Dosage and route of administration

The instructions for use indicate: the dose of Curantil is selected depending on the severity of the disease and the individual reaction of the patient.

1. With IHD, taking 75 mg 3 times a day is recommended. If necessary, the daily dose can be increased under the supervision of a doctor.
2. To reduce the aggregation of platelets, Kurantil is prescribed in a dose of 75-225 mg / day in several doses. In severe cases, the dose may be increased to 600 mg / day.
3. For the prevention of influenza and acute respiratory viral infection, especially during epidemics, Curantyl N25 and Curantil 25 are prescribed 50 mg (2 tablets). or 2 dragees) / day in 1 reception. The drug is taken once a week for 4-5 weeks.
4. To prevent recurrence of acute respiratory viral infections in frequently ill patients with respiratory viral infections, Kurantil N25 and Curantil 25 are prescribed 100 mg / day (2 tab. or dragee 2 times / day with an interval between doses of 2 hours). The drug is taken once a week for 8-10 weeks.
5. For the prevention and treatment of cerebral circulation disorders, as well as for prevention, 75 mg 3-6 times / day are prescribed. The maximum daily dose is 450 mg.

Tablets should be taken on an empty stomach, not breaking down and not biting, squeezed with a small amount of liquid. The duration of treatment is determined by the doctor.

Side effects

The tolerability of the drug is usually very good, but the side effects were still diagnosed. Most often, patients complain of digestive disorders, epigastric pain, heart problems and skin reactions.

It is shown by the following signs:

• myalgia;
• redness of the face;
• nausea;
• diarrhea;
• headaches (possibly dizziness);
• increased heart rate;
• allergy (in the form of cutaneous manifestations).

When appointing patients with unstable pressure should take into account the hypotensive effect of "Curantil".

Overdose

In the reviews about Curantil noted that when an overdose of the drug can be observed a decrease in blood pressure, tachycardia, angina pectoris, hot flashes, dizziness and weakness.

special instructions

Because tea and coffee contain xanthine derivatives, when they are used together, the vasodilating effect of Currantil may decrease.

As a result of lowering blood pressure, which is due to the action of dipyridamole, the speed of psychomotor reactions and the ability to concentrate attention may worsen. For this reason, during treatment it is recommended that care should be taken when driving vehicles and performing potentially hazardous activities.

Drug Interactions

When using the drug, it is necessary to take into account the interaction with other drugs:

1. With simultaneous application, Curantil enhances the effect of antihypertensive drugs.
2. When combined, Couantil can weaken the anticholinergic effects of cholinesterase inhibitors.
3. With simultaneous use of xanthine derivatives weaken the vasodilating effect of Curantil.
4. With the simultaneous use of Curantil with anticoagulants or acetylsalicylic acid, the antithrombotic effect of the latter increases and, accordingly, the risk of hemorrhagic complications.

Reviews

We picked up some responses from people who took the drug Kurantil:

1. Yana. With the aggravation of viral infections, I was prescribed the drug Kurantil. The pill took 2 weeks, the immunity became stronger, the high temperature was already 2-3 days. Pills are sold in a hard shell, so you can drink them even without water. I am happy with this appointment, I often recall this drug during the seasonal epidemic.
2. Svetlana. Kurantil children are prescribed for colds from 12 years. We were recommended by a pediatrician at 10 years old. I bought these pills, several times I misunderstood the instructions, but the child did not cure this way. It is dangerous, because of age mismatch. Therefore, if the doctor prescribed Kurantil - the instruction for use should be studied first, it is better to be safe.
3. Olga. The whole pregnancy was observed in the ordinary women's consultation, there I was discharged "Kurantil." It was motivated by the fact that bad indications on blood coagulability. Have written a free prescription, the medicine cost about 300 rubles, which is not cheap at the appointment to drink it all pregnancy. I decided to study the question with this medicine. I read at the forums of medical workers that nowhere in the world "Kurantil" is not appointed, since its effectiveness is not proven. And only in Russia it is recommended to appoint doctors for certain violations. He did not accept it, gave birth to a normal healthy child.

Analogues

A medical preparation at a concentration of 75 mg is not cheap, so many patients prefer cheaper conservative treatment. Choosing a reliable analogue of Curantil, it is recommended to pay attention to such medicines:

• Parsedil;
• Trombonyl;
• Dipyridamole;
• Coribon;
• Apricor;
• Persantin;
• Angina.

Before using analogues, consult your doctor.

Storage conditions and shelf life

Store the instructions at a temperature not exceeding 300C.

Shelf life 25 - 5 years, drug in the form of tablets - 3 years.

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