Atrovent for inhalations: instructions for use

Atrovent is one of the effective drugs that is widely used for the treatment of bronchopulmonary diseases.

The active substance of the drug is ipratropium bromide, which blocks acetylcholine receptors in the muscles of the bronchi, resulting in decreases the secretion of mucosal glands, spasm of the bronchi with negative effects of pathogenic and irritating factors, such as tobacco smoke, cold or the blue air.

On this page you will find all information about Atrovent: the full instruction on the application for this medicine medium, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already applied Atrovent. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Broncholytic drug - blocker of m-holinoretseptorov.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much does Atrovent cost? The average price in pharmacies is at the level of400 rubles.

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Form of issue and composition

In 1 ml of solution for inhalation contains:

• Active substance: 261 μg (, 61 mg) of ipratropium bromide monohydrate, corresponding to 250 μg (, 5 mg) of ipratropium bromide anhydrous.
• Excipients: benzalkonium chloride, disodium edetate, sodium chloride, hydrochloric acid, purified water.

To 20 ml in a bottle of dark glass, ukuporenny stopper-dropper and a screw cap. The bottle with instructions for use is placed in a cardboard box.

Pharmacological effect

Quite often bronchospasm arises as a reaction to the inhalation of cold air, cigarette smoke or under the influence of a variety of chemicals. Bronchospasm can develop under the influence of the vagus nerve. Active ingredient Atrovent helps prevent bronchospasm caused by any of the listed reasons.

The maximum effect after application of the drug comes in a few hours. The drug significantly improves breathing in bronchial asthma. Atrovent aerosol is practically not absorbed, as the absorption of the drug is very low. The drug is not absorbed from the digestive tract, it is very poorly soluble in fats and extremely weakly penetrates through the biological membranes. He does not cumulate.

Indications for use

Atrovent according to the instructions is prescribed for chronic obstructive pulmonary disease (including emphysema and chronic bronchitis), mild and moderate bronchial asthma, which is accompanied by diseases of the cardiovascular system.

Contraindications

It is not recommended to take the drug with individual sensitivity to the composition, also to pregnant women, especially in the first trimester-pregnancy. In 2 or 3 trimester of pregnancy or with breastfeeding, Atrovent is prescribed very rarely and only in cases of necessity after consultation of a gynecologist.

In pediatrics, the drug is prescribed to children after 5 years. With caution take the drug people suffering from closed glaucoma, kidney failure or in acute urinary tract diseases.

Application in pregnancy and lactation

Contraindicated use of the drug Atrovent H in the I trimester of pregnancy. Appointment of the drug in the II and III trimesters of pregnancy is possible only if the intended benefit of therapy for the mother exceeds the possible risk to the fetus.

It is not known whether Ipratropium bromide is excreted in breast milk. However, it is unlikely that ipratropium bromide, especially with inhalation, can be delivered with milk to the body in significant quantities. But during the use of the drug Atrovent, breastfeeding mothers should be careful.

Instructions for use

The instructions for use indicate that Atrovent is for adult patients and children who are already six years old:

Standard doses of maintenance treatment:

• Adults and children from 12 years:2 ml (, mg) 3-4 times a day. The maximum dose / day is 8 ml or 2 mg.
• Children 6-12 years old:1 ml (, 5 mg) 3-4 times a day. The maximum dose / day is 4 ml or 1 mg.
• Children up to 6 years of age:on, -1 ml (, 5 mg) 3-4 times a day. The maximum / dose is 4 ml or 1 mg.

It is important to remember that 20 drops make up 1 ml of the atrovent solution. In 1 drop of the drug contains 0, 125 mg of ipratropium bromide.

Immediately before inhalation, a single dose of the drug is diluted,% with a solution of sodium chloride to a volume of 4 ml, and poured into a nebulizer. The duration of the procedure depends on the expenditure of the diluted solution. The remaining solution is poured. When diluting a large volume, the solution is stored for no more than 24 hours in the refrigerator. Before the next use, it is heated to 20 ° C. The atroent solution is suitable for use by different types of nebulizers, and also by a centralized oxygen system. In this case, the flow rate is 6-8 liters per minute.

Aerosol instructionfor inhalation

The standard dosage for adults and children over 6 years is 2 doses 4 times a day.

Before using the new Atrovent balloon, you must press the valve twice before the aerosol cloud appears. If the balloon is not used for several days, it is sufficient to press the valve once to create a cloud of aerosol.

If a little solution remains in the container when using the number of doses indicated on the package, it should nevertheless be replaced. This is because the content of the active substance released by inhalation decreases.

The tip of the cylinder must be kept clean. It is not forbidden to rinse it with water and detergent, but afterwards it must be thoroughly rinsed with water.

Side effects

The instructions to Atrovent indicate that most often the drug causes the following side effects:

• Supraventricular tachycardia, palpitations and dizziness;
• Laryngospasm, Quincke's edema and disruption of accommodation;
• Cough, paradoxical bronchospasm and local irritation;
• Skin rash, swelling of the lips, tongue and face;
• Dry mouth, increased heart rate and headache;
• Constipation, urinary retention and diarrhea;
• Nausea, vomiting and atrial fibrillation;
• Urticaria, itching and spasm of the larynx.

In case of accidental ingestion of Atrovent in the eyes, there may be a paresis of accommodation, an increase in intraocular pressure, blurred vision and dilated pupils.

Overdose

According to the reviews about Atrovent, when overdosed with the drug, severe symptoms of systemic anticholinergic action, which include an increase in heart rate, a violation of accommodation and dry mouth.

special instructions

1. In cases of Atrovent application, patients with cystic fibrosis are at increased risk of developing motor tract gastrointestinal depression.
2. The drug is not intended for emergency relief of asthma attacks, since it has a bronchodilator effect later than β-adrenostimulants.
3. Combined use of Atrovent for inhalations combined with Ambroxol, Bromhexin and Berotek is allowed.
4. If after a few days of drug treatment the patient's condition worsens or there is no positive effect after inhalations - the doctor should change the therapy scheme.

Because the product contains disodium edetate and benzalkonium chloride, which in some cases can cause narrowing of the lumen of the bronchi, Atrovent may cause the appearance of bronchospasm.

Drug Interactions

Doctors can prescribe taking Atrovent with Lazolvan or Berotek. The effect of muscle relaxation is enhanced by the 2-adrenergic formulations. Anticholinergic effects may be supplemented by quinidine or antiparkinsonian drugs or tricyclic antidepressants.

If Atrovent is used with other substitutes for acetylcholine, an additive effect can be observed. If you use the product together with a solution of disodium chromoglycate, this can result in precipitation.

Reviews

The effectiveness of Atrovent is confirmed by the feedback of those who use it as supportive or curative therapy. They emphasize the good tolerability of the drug and the absence of side effects.

• Roman Viktorovich, Samara: Thanks to the producers of Atrovent. He worked in harmful production, since then he suffocates. And it's much easier with him, and seizures became less frequent.
• Elena R. in Moscow: I used to be very worried about my father - he is 65 years old and he has a diagnosis of "obstructive bronchitis". On the recommendation of doctors, he bought Atrovent an aerosol. He always carries it with him and yesterday he injected himself on the street. Pleased - the spasm quickly passed. Now I'm calm for him.

Analogues

To Atorvent analogues having the same active substance are:

• Ipravent;
• Atrovet N;
• Ipratropium bromide monohydrate;
• Ipratropium Steri-Neb.

Before using analogues, consult your doctor.

Storage conditions and shelf life

The main condition for storing Atrovent is the temperature regime. It can be kept under normal conditions, but do not allow freezing. Also, the storage of the medicinal product should be inaccessible to children.

The drug Atrovent has a fairly long shelf life after expiration, which it is prohibited to use. You can keep the medicine for at least five years.

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