Kompligam: instruction on the use of the drug in injections

Complicates in injections: instructions for use, analogues, price

Kompligam(also applicable to the full commercial name Compligam) refers to complex preparations of B vitamins. It is produced in a solution for intramuscular injection in ampoules of 2 ml.

Externally, a solution of a reddish color, with a specific odor, is transparent. 1 ml of the solution contains 50 mg of thiamine (vit B1), 50 mg of pyridoxine (vit B6), 500 mg of cyanobobalamine (vit B12).

As an additional component (analgesic effect), the drug includes 10 mg / ml lidocaine (should be remembered in the presence of allergic reactions).

In one ampoule contains 2 ml of the drug, therefore, the above dose should be multiplied by 2 to get the composition of the drug for 1 ampoule.

Also, the components of the drug are benzyl alcohol, sodium polyphosphate, potassium in the form of hexacyanoferrate, sodium hydroxide to stabilize the pH, injection water.

The neuroprotective properties of B vitamins lead to positive effects in inflammatory or degenerative diseases of the peripheral nervous system, as well as the musculoskeletal system (including the spine). At high dosages, Kompligam also has an analgesic effect, can increase blood flow, normalize the account of vitamin B12 hemopoiesis processes, as well as normal metabolic shifts in the cells of the nervous system.

If we consider separately the components, vitamin B1 participates in the processes of carbohydrate metabolism, as well as the Krebs cycle (the main biochemical cycle of the body) with the synthesis of ATP.

Vitamin B 12 stimulates hemopoiesis, is involved in biochemical transformations of the synthesis of the myelin sheath, reduces pain associated with peripheral nerve damage. It can stimulate the exchange of nucleic acids indirectly through the effects of folic acid through its activation.

Lidocaine is a local anesthetic, in particular, it reduces pain from injection.

Pharmacokinetics after injection into the muscle Kompligam quickly enters the blood (significant doses are determined as early as 15 minutes after administration. This applies to all components.

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Separately, thiamine is distributed in leukocytes and plasma by 10-15%, and erythrocytes up to 70%. Has no stocks in the depot.

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Can penetrate through gistogematicheskie barriers, including excreted in breast milk.

Pyridoxine significantly binds to plasma proteins, is also distributed throughout the body, can penetrate through tissue barriers and enter the breast milk. Can form a depot in the liver.

Kompligam is excreted mainly in the urine.

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Indications

There are a lot of indications for using the drug:

• Diabetic, alcoholic and other types of polyneuropathy
• Neuritis, including retrobulbar neuritis
• Mononeuropathies (tunnel syndromes)
• Neuropathy of the facial and other nerves.
• Neuralgia of the trigeminal, lumbosacral, intercostal and other nerves
• Ganglionvrites (including after herpetic lesions)
• Pain in vertebrogenic pain syndromes (lumboschialgia, cervicocranygia, cervicalgia, thoracalgia, lumbargia), and also other manifestations of osteochondrosis of various departments (cervical, thoracic, lumbar) in the complex therapy.

Contraindications

There are a number of contraindications for the use of Compligam:

• Decompensated heart failure.
• Pregnancy and lactation.
• Child age (up to 16-18 years) due to lack of safety data.
• Allergic reactions and reactions of intolerance

Mode of application

The drug Kompligam is used intramuscularly, the injection is made deep, daily on for 1-2 weeks, then go on to take tablets of B vitamins or injections 1 time in a week.

Side effects

Side effects are rare. The most common allergic reactions (more often skin manifestations), increased sweating, palpitation, development of acne

Overdose:
Overdose (as well as the development of its effects) occurs with rapid administration or a significant excess of recommended doses. Systemic reactions: dizziness develops, rhythm failure, convulsions. Specific treatment does not exist. Symptomatic therapy is performed.

special instructions

When using injections, Complymi should follow special instructions:

• Vitamin B 6 is not used together with levodopa due to the decrease in the effects of the latter.
• It is not recommended to have a joint reception with epinephrine and norepinephrine because of the risk of heart effects due to the increased effects of the latter with lidocaine, which is part of Compligam.
• Vitamin B1 is unstable in solutions of sulfites, it is not recommended to use it with barbiturates, citrates, carbonates and copper preparations.
• Undesirable rapid administration of the drug due to the risk of arrhythmia and dizziness.
• Vitamin B 12 can not be used with vitamin C, drugs containing salts of heavy metals.
• Cyanocobalamin is incompatible with ascorbic acid, salts of heavy metals.
• Does not affect the speed of psychomotor reactions and the ability to drive.

Storage conditions

Kompligam kept in a place inaccessible to young people, it is necessary to store it in the refrigerator door (temperature 2-8 degrees). Do not freeze or store / transport at temperatures below 2 degrees Celsius. Shelf life should not exceed two years.

author's material

Analogues

Analogues of the drug are all complex preparations of B vitamins. Among them are the most famous: Kombilipen, Milgamma, Neurobion, Trigamma, Vitagamma and others.

Price

Complicates in injections are released from pharmacies according to the prescription of the treating doctor. Average prices are quite affordable and are:

• Packing 5 ampoules per 2 ml 140-190 rubles.
• Packing 10 ampoules of 2 ml 220-270 rubles.

Do not self-medicate. Before using COMPLIMAM, consult your doctor!

Alexey Borisov (a neurologist)

Practicing neurologist. He graduated from Irkutsk State Medical University. Works in the faculty clinic of nervous diseases. Read more ...

A source: https://neurosys.ru/lechenie/lekarstva/kompligam

"Kompligam instructions for use, reviews, analogues

The drug "Kompligam the instruction on which application will be given to your attention further in the article, is a combined vitamin remedy, which enters immediately into two pharmacological groups: "Vitamins as well as "Adaptogens and tonic aids. "

The named preparation is used for various diseases of the nervous system and in cases of necessity to increase the general tone of the organism and its resistance to the influence of unfavorable factors.

What is included in the Compligam facility

As the instructions for use, applied to the drug "Kompligam" indicate, the following substances contribute to the inflammatory and degenerative processes in the central nervous system:

• Thiamine hydrochloride, which affects the metabolic processes occurring in the neural tissues;
• pyridoxine hydrochloride, involved in the metabolism of proteins, as well as fats and carbohydrates (in part);
• cyanocobalamin, stimulating the process of hematopoiesis, reducing pain and stimulating nucleic acid metabolism by the activation of folic acid;
• and lidocaine, which has local anesthetic properties.

But in the application of this or similar remedies it should be remembered that these vitamin complexes can not be used thoughtlessly.

Assigning them to yourself and guided at the same time only by positive feedback from friends, you can do harm your body, which manifests itself in violations of the liver, hair loss, as well as in the appearance of acne on the face and the body. Decide whether the patient needs the drug "Complymi and only the doctor can select the appropriate dosage.

At what diseases is used the drug "Kompligam"

Combined drug "Kompligam" (the instruction to which is offered to your attention), is effective in the following cases:

• pain and numbness arising from neuralgia of the facial nerve;
• with polyneuropathy (especially with the diabetic or alcoholic form of the disease);
• with peripheral paresis (weakening of muscles);
• Neuralgia (including defeat of the trigeminal or intercostal nerves);
• in the presence of a pain syndrome associated with myalgia or radiculopathy;
• in the case of nocturnal muscle cramps (especially in elderly patients);
• with herpes zoster;
• with neurological manifestations of osteochondrosis.

The drug "Kompligam instructions for use, analogues

The properties of the described drug also have the properties listed above.

They have an absolutely equal composition and approximately the same cost, on the basis of this, doctors advise to choose for treatment the drug that is available at the moment in the pharmacy network.

The vitamin complex "Kompligam as well as its analogs, is available in several dosage forms: in the form of a solution for injections or in the form of tablets.

Features of the application of the "Kompligam" (nyxes)

Instruction for the use of the described agent indicates that per day its maximum dose for injections is one ampoule of the substance.

In the case of severe pain syndrome, this dose is used during the first 10 days of treatment.

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And then it is significantly reduced by injections in one or a couple of days (one ampoule up to three times a week).

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The drug is injected deeply into the gluteus muscle, which allows it to gradually enter the bloodstream and be absorbed optimally. In cases, if for some reason the patient himself must do this, he is offered to inject into the anterior part of the thigh (in his upper third).

How are the "Compllyam" tablets taken?

On how to properly take the drug "Kompligam" (tablets), the instruction for use says the following:

• it is best to take them after eating;
• Do not chew, crush or dissolve in liquid;
• for the fastest passage of active substances into the stomach and sucking them into the blood, the drug should be washed down with plenty of water, compote (not acidic!) or weak tea.

The duration of the preventive or therapeutic course of taking the drug is determined by the doctor, taking into account the nature of the disease and the severity of its symptoms. Most often it is two weeks, but longer therapy is possible.

To avoid an overdose, long-term courses do not assign high doses of the drug.

Manifestations of an overdose of the drug "Kompligam"

Symptoms of overdose appear only after the simultaneous administration of more than five ampoules of the drug. In this case, the patient may experience convulsions, dizziness, nausea, manifestations of arrhythmia and bradycardia, as well as a sensation of tingling and numbness in the upper and lower extremities.

A special antidote, the medicine "Compllygam" (the instruction to it is provided in this article) does not have, therefore, in case of overdose, symptomatic treatment of the patient is carried out.

If necessary, he is placed in a hospital. But, as a rule, the excess amount of active substances of the described drug is already excreted in the urine within 24 hours.

Contraindications for the use of the drug "Kompligam"

For the use of injections or "Kompligam" tablets, there are some limitations.

Thus, the described vitamin complex is not prescribed in cases when the patient is diagnosed with heart failure in acute or decompensated form, as well as in cases of an increased sensitivity to the components of the named preparation.

As the instruction on application applied to the drug "Kompligam" emphasizes, to prescribe this remedy to children is not recommended, because the impact on the children's body of the components that make up its structure has not been studied.

Patients taking "Complymen alcohol is contraindicated, since it can enhance the action of lidocaine, which is part of the drug, and thus lead to the blocking of the respiratory center, and this is fraught with lethal outcome.

Specific effects of the drug on the human body

The details of the effects of the drug are described in detail by the instructions for use applied to the drug "Kompligam". Reviews of doctors and patients about the named preparation also underline its positive impact on the human body.

So, experts pay attention to the high effectiveness of the drug in its complex use in the therapy of a number of pathologies of the peripheral nervous system. Entering into the solution for injection lidocaine allows you to make them painless and, accordingly, comfortable for patients.

Some patients note an increase in general tone, a feeling of high energy, cleansing the skin and a marked improvement in the condition of the hair and nails as a consequence of taking the described drug. One can not but say about the low price for this product (it fluctuates around 300 rubles in the territory of the Russian Federation).

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But the drug "Kompligam" has some side effects, which can be expressed in transient disorders from the heart and vessels (with rapid administration). This, as a rule, manifests itself in the form of dizziness, sweating and rapid heart rate.

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Use of the drug by persons who are addicted to allergic reactions, can provoke the appearance of skin rash and itching.

And in some cases, the result of using the described vitamin complex was an acne that appears on the face and chest of the patient.

All cases of worsening of health as a result of taking this vitamin complex should immediately notify the attending physician in order to review the appropriateness of its use.

Conditions of drug storage

As advised by the instructions for use applied to the injection for Compligam, this form of the drug is best stored in the refrigerator.

This condition is due to the fact that the substances that make up the drug are afraid of direct sunlight and require a temperature of no higher than + 8 ° C.

Tablets the same "Kompligam" can be stored at room temperature, but in a dark place. By the way, the bathroom for this purpose is not suitable, because it has high humidity, and the said product, as well as other tabletted forms, is afraid of moisture.

A source: http://.ru/article/227936/kompligam-instruktsiya-po-primeneniyu-otzyivyi-analogi

Compliments in tablets and injections - when appointed, composition, mechanism of action, contraindications and reviews

From pain in the muscles of the back, with radiculitis, the drug Kompligam is used. The drug is available in two formats, taken orally or parenterally for various purposes.

It consists of B vitamins, plus additional components that enhance their effect. Read the instructions for using the medication to use it correctly.

The drug Kompligam

According to the pharmacological classification, the drug refers to complex vitamin preparations, multivitamins.

The composition includes only one group of vitamins - B, which have neurotropic properties.

In high concentrations, the drug supports the functions of the nervous system and the processes of hematopoiesis, participates in the synthesis of important for the body biological substances.

Medication is available in two formats - tablets and solution for intramuscular injection. Familiarize yourself with their composition:

Solution	Pills
Description	Pinkish-red liquid with a specific flavor	Round white with a slight pink tinge
Concentration of composite substances, mg per 1 ml / 1 pc.
Thiamine hydrochloride (B1)	50	5
Pyridoxine hydrochloride (B6)	50	6
Cyanocobalamin (B12)	,	9
Lidocaine hydrochloride	10
Pantothenic acid (B5)	15
Nicotinamide (B3)	60
Folic acid (B9)	600
Riboflavin (B2)	6
Composition	Water, benzyl alcohol, sodium hydroxide solution, sodium poly- or tripolyphosphate, potassium hexacyanoferrate	Biotin, choline, inositol, paraaminobenzoic acid
Packaging	By 2 ml in ampoules of dark glass, a pack of 5 or 10 pieces	30 or 60 pcs. in a pack

Pharmacodynamics and pharmacokinetics

The combined preparation contains a complex of B vitamins, which are neurotropic.

They have a positive effect on inflammatory and degenerative diseases of the peripheral nervous system and motor apparatus.

High doses of vitamins have an analgesic effect, accelerate blood flow, normalize the nervous system and the processes of hematopoiesis.

• Vitamin B1 thiamin takes part in the metabolism of carbohydrates, which are important participants in the metabolism of the nerve tissue of the Krebs cycle, regulates the decarboxylation of alpha-keto acids.
• Pyridoxine B6 takes part in the metabolism of proteins, carbohydrates and fats, cyanocobalamin B12 helps the synthesis of myelin shell of nerve tissues, stimulates hemopoiesis, relieves pain, stimulates nucleic acid metabolism, activates folic acid.
• Nicotinamide B3 normalizes the function of the joints, reduces pain in osteoarthritis, dilates small vessels, improves blood microcirculation.
• Pantothenic acid B5 is involved in the metabolism of carbohydrates, fats and proteins, it helps to normalize the functioning of the nervous system, heart and blood vessels, helps with arthritis.
• Folic acid B9 is indispensable for supporting the work of hematopoiesis, the immune system, helps with psoriasis.
• Riboflavin B2 helps to produce red blood cells, regenerates and restores the body tissues.

The additional substance of the solution formulation - lidocaine - has a local anesthetic effect.

After intramuscular or oral administration of the preparation, the compound substances are rapidly absorbed and enter the blood, distributed in erythrocytes, leukocytes and blood plasma unevenly.

Part of the components of the drug binds to blood plasma proteins, penetrate through blood-brain and placental barriers.

Metabolism of neurotropic vitamins occurs in the liver, where they are oxidized with the formation of active and inactive metabolites. The withdrawal from the body is uneven: from 30 minutes to two days.

Metabolites and permanent components are excreted in the urine.Because of the natural presence in the human body of the B group vitamins, the dose for the use of the drug should be carefully selected.

Indications for use

Depending on the form of release of medicines, their indications for use, indicated in the instructions enclosed in each pack, differ.

The Kompligam tablets have more universal use factors than the solution, because the latter is intended for topical application, relief of pain.

Prescribing drugs should be done by doctors.

Complymen in tablets

Indication for the use of multivitamin tablets is the prevention or lack of vitamins of group B, choline, inositol, paraaminobenzoic acid.

This means that the medicine should be used as a biologically active food additive (BAD), which acts as an additional source of composite substances.

This need is manifested during the period of growth of children, with chronic fatigue in adults.

Compliments of injections

A narrower focus is the indications for use for the solution. The drug is used for pathogenetic and symptomatic therapy of diseases and syndromes of the nervous system:

• neuropathy, diabetic or alcoholic polyneuropathy;
• neuritis, polyneuritis, a retrobulbar variety of the disease;
• peripheral paresis, including lesion of the facial nerve;
• neuralgia, including damage to the trigeminal nerve and intercostal nerves;
• radicular pain syndrome, myalgia;
• night muscle cramps, especially in the elderly;
• plexopathy, ganglionitis, herpes zoster;
• dorsalgia of the thoracic spine;
• radiculopathy, lumboschialgia, muscular-tonic syndrome.

As well as indications for use, the way of use and dosage of preparations depend on the form of release and are specified in the instruction.

The injections of the Kompligam solution are intended for intramuscular injection. The tablets are administered orally, taken internally without chewing or grinding.

The exact dosage, course and multiplicity of medication is prescribed to the patient by the attending physician.

Complyms in ampoules

The injections of Kompligam are prescribed in severe pain syndrome. They are deeply intramuscularly injected with 2 ml daily for 5-10 days.

After this period, doctors examine the patient, establish the effect and either transfer it to oral intake of a tablet form, or for rarer injections of the drug - up to 2-3 times / week with a course of 14-21 day.

Compliments of a pill

According to the instructions for use, Kompligam tablets are prescribed only to adult patients. Multiplicity of medication is once a day with food intake.

The course of application of the tablet form of the drug lasts for a month. You can repeat it with the permission of the attending doctor with a mandatory break of at least 30 days.

Do not adjust the dosage yourself or prolong the course of taking the drug.

special instructions

If the solution is injected quickly, systemic reactions may develop at the injection site. The patient will feel dizzy, develop an arrhythmia, there will be convulsions.

The instructions for use do not contain information on whether tablet taking or injecting of Complement B affects the concentration and weakening the speed of psychomotor reactions, therefore, during the management of transport and dangerous mechanisms against the background of therapy, the remedy must be observed caution.

In pregnancy

Doctors forbid the use of the drug to compensate for the lack of B vitamins or the relief of pain syndromes during pregnancy and breastfeeding.

This is due to the fact that the components of the composition penetrate the placental barrier, are capable of damaging the developing fetus.

When lactated, the drug penetrates into breast milk, and can also cause negative reactions in the newborn.

In childhood

Due to the lack of research on the safety and efficacy of the medication, as indicated in the instructions for use, it is not recommended for use in children and adolescents under 12 years.

If it is necessary to use such vitamin preparations, children should consult a doctor about choosing a safer analogue.

After reaching the age of 12 years, the dose of the drug is adjusted by the doctor, based on the age, weight of the child.

In case of violations of the kidneys and liver

Kompligam tablets are taken under medical supervision, especially in renal or hepatic insufficiency, because the metabolism of components and their withdrawal occurs with the help of these organs. With severe liver damage due to the presence of lidocaine in the solution, procedures based on it are categorically prohibited, otherwise there is a risk of tissue damage, according to doctors.

Drug Interactions

The possible drug interaction of the drug in question with other agents is indicated in the instructions for use:

• pyridoxine weakens the action of Levodopa, therefore this combination is not recommended;
• In combination with epinephrine and norepinephrine, the effect of lidocaine is enhanced, so it should be avoided simultaneous reception of local anesthetics due to increased risk of side effects on a heart;
• thiamine decomposes in solutions containing sulfites, is unstable in alkaline and neutral liquids;
• It is forbidden to combine thiamine with carbonates, barbiturates, citrates, preparations based on copper;
• enhances the Amelotex effect;
• cyanocobalamin is incompatible with vitamin C, heavy metal salts;
• vasoconstrictors increase the time of anesthetic action of the drug, can cause tachycardia;
• with caution combine the drug with quinidine, cimetidine, Digitoxin, Amiodarone.

Kompligam and alcohol

Doctors categorically do not recommend combining the drug with alcohol. This is due to the increased load on the liver, the negative effects of ethanol on its tissues in itself.

A solution containing lidocaine, in combination with alcohol or alcohol-containing beverages / drugs, can enhance the action of the anesthetic, lead to blockage of the respiratory center, and death.

Side effects

The instruction on the use of B vitamins in preparations indicates the possible development of negative side effects:

• allergic reactions;
• itching, hives, irritation on the skin, burning, flushing, swelling;
• shortness of breath, angioedema, anaphylactic shock;
• increased sweating, tachycardia;
• the appearance of acne;
• nausea, dyspepsia, vomiting;
• disorientation, angioedema;
• nervousness, photophobia, increased pressure;
• diarrhea, drowsiness, bradycardia, sensation of cold or heat;
• mental excitement, transverse heart block;
• collapse, diplopia.

Overdose

With rapid injection of injections of solution or taking too much of a dose of a tablet drug, it is possible to develop dizziness, arrhythmia, seizures, vomiting, blanching of the skin.

Treatment for overdose with tablets includes gastric lavage, the appointment of sorbents. When poisoning with a solution, symptomatic therapy is indicated.

There is no special antidote, the excess is rapidly excreted in the urine throughout the day.

Contraindications

The drug, like any other, there are contraindications, in which its appointment is prohibited due to the development of extremely negative reactions:

• severe or acute form of decompensated chronic heart failure;
• child age, gestation period, lactation;
• hypersensitivity to the component composition of the agent.

Terms of Sale and Storage

The drug in the form of a solution is dispensed by prescription, tablets can be purchased without it. Store the solution is required if the temperature is 2-8 degrees, tablets - up to 25 degrees. Shelf life is two years.

Analogues

Structural and analogous means for the pharmacological group are drugs that have the same active ingredients in the composition or a similar therapeutic effect. The following medicines are in the format of solution and tablets:

• Kombilipen;
• Vitaxon;
• Milgamma preparations;
• Vitagamma;
• Binavit;
• Trigamma;
• Angiovitis;
• Vitamax;
• Heptavit;
• Berrocca.

Price Compligam

Buy Kompligam can be through pharmacies or online departments at prices that depend on the level of trade margins, the form of release of the drug, the number of tablets and ampoules in the pack. The approximate cost will be:

Type of facility	Internet price, in rubles	Pharmaceutical price list, in rubles
Ampoules 2 ml 5 pcs.	172	180
Ampoules 2 ml 10 pcs.	272	290
Tablets 30 pcs.	241	260
Tablets 60 pcs.	256	275

Reviews

A source: http://vrachmedik.ru/721-kompligam.html

Complyma B:

Compligam V

1 ml of the drug Complementa B contains 50 mg of thiamine (in the form of hydrochloride), 50 mg of pyridoxine (in the form of hydrochloride), mg of cyanobalamine, 10 mg of lidocaine (in the form of hydrochloride). Additive components: sodium hydroxide, sodium polyphosphate (sodium tripolyphosphate), potassium hexacyanoferrate, benzyl alcohol, sterile water.

Complymgam B - a complex of vitamins with a neurotropic effect, which stimulates the processes of hemopoiesis, improves circulatory processes, provides local anesthesia, reduces pain syndrome, supplies vitamins. B vitamins are necessary for the functioning of the nervous system.

The complex of these vitamins helps reduce inflammation, reduce the manifestations of degeneration of the nervous tissue, stop degenerative processes in the motor apparatus.

High dosages of the drug Compligam B provide analgesia, accelerate blood flow, improve blood supply to tissues.

Thiamin is necessary for normal metabolism of carbohydrates, important for the functioning of nervous tissue. Thiamine molecules participate in the Krebs cycle.

Thiamine is important for the synthesis of TPP and ATP (molecules that are important for optimal energy metabolism).

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Pyridoxine molecules are involved in synthetic processes for the production of proteins, fat molecules, carbohydrate compounds. Thiamine and pyridoxine mutually potentiate the effects of each other.

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Molecules of cyanocobalamin take part in the development of compounds for the construction of the myelin sheath of nerve endings, optimize processes of hemopoiesis, reduce the pain syndrome associated with the defeat of nerve endings in the periphery, stimulate the exchange nucleic acids. Lidocaine provides local anesthesia.

Complym B is indicated for pathogenetic therapy and for relief of symptoms when:

• Neuropathy;
• Do not lie;
• peripheral paresis;
• polyneuropathy, associated with diabetes, alcohol intake;
• polyneuritis;
• myalgia;
• plexopathies;
• radiculopathy;
• neuralgia of the intercostal nerves;
• retrobulbar neuritis;
• trigeminal neuralgia;
• lumboishalgia;
• root pain syndrome;
• ganglionitis;
• muscular-tonic syndromes;
• nocturnal muscle cramps;
• shingles.

If necessary, the severe pain syndrome should be administered 1 ampoule of the drug 1 time / day. The introduction is carried deep into the muscle.

Course - 5-10 days. Further transfer to oral medications or recommend injections 1 time / 2-3 days.

The course can be extended for another 14-21 days.

Application of the drug Compligam B may be accompanied by:

• hypersensitivity reactions;
• acne;
• a tachycardic attack;
• difficulty breathing;
• hyperhidrosis;
• anaphylaxis;
• itching of the skin;
• angioedema.

Compliments B are not assigned when:

• hypersensitivity to the active or additive components of the dosage form;
• severe forms of myocardial insufficiency of a chronic nature;
• acute forms of myocardial insufficiency;
• indications in pediatrics.

The drug is not recommended to prescribe to pregnant patients. The application is possible only if there is real benefit for the patient, which considerably exceeds the possible risks for the child to be born.

The drug, the group of drugs The possible result of interaction with the drug Kompligam V

Sulphites	Destruction of the active component of the drug Complym B
Alkaline solutions	Incompatibility
Neutral solutions for injections	Chemical incompatibility
Preparations of copper	Incompatibility
Levodopa	Incompatibility
Ascorbic acid	Chemical incompatibility
Salts of heavy metals	You can not share

When the therapeutic dosages of this drug are exceeded, there are attacks of arrhythmia, dizziness, convulsive reactions. Therapy should be prescribed by a doctor in accordance with the symptoms.

The drug Kompligam B is available in the form of a solution for injection. The preparation is as follows:

• 5 ampoules of 2 ml / package;
• 10 ampoules of 2 ml / package.

The drug Kupligam B should be stored in a refrigerator. Ampoule storage temperature is 2-8 degrees Celsius. It is inadmissible to freeze the solution, transport at a temperature of up to 2 degrees Celsius.

The drug is suitable for use for 24 months. The drug should not be stored in children's places. The use of an expired solution may be potentially hazardous to health.

Kombigamma, Neuromax, Neovitam, Kombilipen, Vitakson, Neurovitan, Neurorubin, Neuromultivit, Neurolec, Milgamma, Neurobex, Nerviplex-N, Neurobion, Neurobex Forte, Unigamma.

See also the list of analogues of the drug Kompligam V.

thiamin, pyridoxine, cyanocobalamin

A11EX

Sotex

When a paresthesia appears, the doctor should review the dosage of the drug used.

The drug can mask the clinical picture of malignant anemia, myelosis.

Do not use the drug intravenously.

Description of the preparation «Complyma B"On this page is a simplified and augmented version of the official instructions for use. Before purchasing or using the drug, you should consult with your doctor and read the annotation approved by the manufacturer.
Information about the drug is provided solely for informational purposes and should not be used as a guide to self-treatment. Only the doctor can decide on the appointment of the drug, as well as determine the dose and methods of its use.

Number of views: 11606.

A source: http://www.piluli.kharkov.ua/drugs/drug/kompligam-v/

Instructions for use

Complymgam B is a medicament used to treat and prevent diseases of both the central and peripheral nervous system. Pharmacologists attribute Complymium to two groups - vitamins and drugs that have a tonic effect.

The drug Kompligam is produced in injectable and tablet form. The drug can be purchased at pharmacies. Average prices in pharmacies in Russia's cities are within:

• Complym B (solution for injection), 10 ampoules of 2 ml - price from 206 to 265 rubles;
• Complicates In (tablets), 30 pieces - from 190 to 250 rubles.

Effect of the drug on the body

Instructions for use, applied to the drug, states that the drug acts on the inflammation and degenerative processes occurring in the central nervous system. Complym B also has a multivitamin, analgesic, local anesthetic effect. This is facilitated by the components that make up the preparation:

1. Thiamine hydrochloride (vitamin B1). It affects the processes of metabolism that occur in the nervous tissues. Vitamin plays an important role in the processes of carbohydrate metabolism.
2. Pyridoxine hydrochloride (vitamin B6) takes an active part in the metabolism of proteins and partially - fats and carbohydrates.
3. Cyanocobalamin (vitamin B12) stimulates hematopoiesis, nucleic acid metabolism and reduces pain.
4. Lidocaine. Has local anesthetic effect.

Patients should remember that the drug can be used solely for the purpose of the treating doctor. Do not engage in self-targeting, taking into account the positive feedback of those who used the drug.

This approach to treatment can have a very negative impact on health - from acne to the violation of the liver.

That's why you need to visit a doctor who decides whether it is expedient for you to use Complly, and if necessary, prescribe a dosage.

Indications for use

Medicamentous drug Kompligam V is used to treat patients with neurological diseases. The drug is actively prescribed for the following diseases:

• Neuropathy and polyneuropathy;
• neuritis, polyneuritis;
• peripheral paralysis;
• neuralgia;
• with pain syndrome;
• muscle cramps developing at night, especially in elderly patients;
• plexopathy, ganglionitis;
• radiculopathy, lumboeishalgia, muscular-tonic syndromes.

The instructions for use say that the daily maximum dose is 1 ampoule of the drug Kompligam.

If the pain syndrome manifests itself clearly, then this dosage can be used during the first 10 days of treatment.

After that, the dose should be reduced and the therapy given by this medicine in 1-2 days, i.e. 1 ampoule of the drug should be administered up to 3 times a week.

It is recommended that the medication is deeply inserted into the muscle of the buttock. This contributes to the gradual receipt of the drug in the blood, as well as its optimal assimilation. If the patient, for whatever reason, needs to take an injection himself, then the drug should be injected into the upper third of the thigh area.

We will become acquainted with the instruction on the use of tablets to Compligam V. The drug should be consumed after ingestion, swallowing without chewing or chopping.

To active components of the drug more quickly absorbed into the blood, it is recommended to drink the pills with a glass of water (you can sweet compote or slightly boiled tea).

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The duration of the drug is determined only by the doctor, taking into account both the severity of the symptoms of the disease and the individual characteristics of the organism.

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In general, the duration of therapy is 14 days, but a longer reception is possible.

However, with prolonged treatment, high doses of the drug are not prescribed in order to avoid an overdose.

To get the expected result from treatment with Complementa B, you need to know some of the nuances of the application. We will get acquainted with them in more detail.

1. The drug can not be administered quickly, since there is a threat of development of systemic reactions of the body - convulsive state, dizziness, heart rhythm disturbances.
2. Kompligam is not used simultaneously with Levodopa, as the pyridoxine, which is part of the vitamin preparation, weakens its therapeutic effect.
3. If together with Compligam applies Epinephrine and Norepinephrine, then it is possible to increase the side effects on the heart.

What is better for Kompligam B in tablets or in ampoules?

Only the attending physician can answer this question, taking into account the nature of the course of the disease, the individual characteristics of the patient's body.

However, it should be noted that the tablet form is prescribed much less frequently than the injectable form. Most often, the pills are used by people who were previously treated with injections.

Kompligam tablets give good results in the treatment of neuralgia, neuritis, osteochondrosis, polyneuropathies, if the pain symptom is not pronounced. This makes it possible to prevent the development of seizures and maintain a stable state of remission.

Contraindications

Although the drug is well tolerated by patients, however, not everyone can prescribe it. The main bans include the following diseases and conditions:

• decompensated chronic heart failure, taking place in acute and severe form;
• individual immunity of any constituents of the drug;
• children's age (due to lack of necessary research);
• pregnancy, breast-feeding (because of the high content of vitamin B6 (100 mg).

Side effect

Both tablets and injections can cause the patient to develop unwanted reactions from various organs and body systems. Let us consider in more detail how an organism can react to the application of Compligam:

• reactions of the skin, which are accompanied by itching, hives;
• the individual intolerance of the drug manifests itself by difficulty breathing, angioedema, up to the development of anaphylactic shock;
• increased sweating;
• cardiopalmus;
• acne.

Patients generally leave feedback on the use of Comligam in the form of injections. There is an effective effect in the pain syndrome. Side effects include increased sweating and heart palpitations.

Analogues

If it is not possible to use Comligam, it can be replaced with analog preparations: in particular, with vitamin complexes that contain vitamins of group B. The most commonly used are: Kombilipen, Milgamma, Trigamma, Vitagamma.

It is necessary to remember: do not self-medicate and replace drugs yourself. This can only be done by a specialist.

A source: http://witamin.ru/vitaminy/vitamin-b/kompligam-b.html