Gynepriston

Ginepristone is a synthetic steroid drug, which is shown to girls and women of almost any age, leading a sexual life and having performed unprotected sexual intercourse in the last 72 hours.

The remedy is not suitable for routine contraception, however it is effective in some cases.

On this page you will find all information about Ginepristone: the full instructions for use on this medication, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already used Ginepriston. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Antigestagenic preparation. Postcoital contraceptive for oral administration.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much does Ginepristone cost? The average price in pharmacies is at the level of450 rubles.

Form of issue and composition

One tablet contains:

• active substance: mifepristone -10 mg;
• auxiliary substances: microcrystalline cellulose, sodium carboxymethyl starch, calcium stearate.

Tablets from light yellow to light yellow with a greenish shade of color of flat-cylindrical form with a facet from two sides.

Pharmacological effect

Synthetic steroidal anti-gestagenic drug, (blocks the action of progesterone at the receptor level), does not possess gestagenic activity. Antagonism with glucocorticoids is noted (due to competition at the level of communication with receptors).

Increases the contractile ability of the myometrium, stimulating the release of interleukin-8 in choroid-epidural cells and increasing the sensitivity of the myometrium to prostaglandins. Depending on the phase of the menstrual cycle, inhibition of ovulation, changes in the endometrium and prevents the implantation of a fertilized egg.

Indications for use

According to the instructions to Ginepristone, mifepristone - the active substance of this anti-gestagenic drug - enhances the contractility of the myometrium, depending on the phase of the menstrual cycle causes a change in the endometrium, a delay in ovulation, or interferes with the implantation of a fertilized egg.

Given the described properties of the active component of Ginepristone, the drug is used for emergency postcoital contraception after unprotected sexual intercourse (or in the event that the applied method can not be considered reliable).

Contraindications

The use of ginepristone is contraindicated in women who have the following pathologies in their anamnesis:

1. Adrenal insufficiency;
2. Chronic renal or hepatic insufficiency;
3. Hypersensitivity to the main or one of the auxiliary components of the formulation;
4. Acute renal or hepatic insufficiency.

Do not take the drug after a long glucocorticosteroid therapy and during breastfeeding.

According to the instructions to Ginepristone, with caution it is recommended to prescribe a remedy to patients in the case of:

1. Severe hypertension;
2. Violations of hemostasis and after taking anticoagulant drugs;
3. Heart rhythm disturbances, chronic heart failure;
4. Chronic obstructive pulmonary diseases, including bronchial asthma.

Application in pregnancy and lactation

Gyneprystone is contraindicated in pregnancy.

You should stop breastfeeding for 14 days after taking the drug.

Instructions for use

The instructions for use indicate that Ginepristone is prescribed by mouth in a single dose of 10 mg (1 tab.) For 72 hours after unprotected intercourse.

To maintain the contraceptive effect, you should refrain from eating 2 hours before the drug and within 2 hours after ingestion.

Ginepristone can be used in any phase of the menstrual cycle.

Side effects

The most common side effects after taking ginepristone are nausea, abdominal pain, dizziness, headache pain, vomiting, spotting, skin rashes, fever, weakness, menstrual irregularity. Reviews about Ginepristone suggest that after taking the drug, severe side effects almost never happen.

Before acquiring Ginepristone in pharmacies, you should also consult a qualified gynecologist.

Overdose

Clinical observations indicate the absence of unwanted reactions even when taking 2 g of mifepristone. At high dosages, the development of a symptom-complex of adrenal insufficiency is possible. Therapy should be performed by a specialist depending on the manifestations of an overdose.

special instructions

1. Ginepristone does not protect against diseases that are transmitted sexually, including from HIV infection and other infections.
2. Gynepriston is not suitable for permanent contraception - it needs to be considered. It is recommended to take this medication after consulting a doctor.
3. It is not recommended to take alcohol before taking the drug, and alcoholic beverages can not be used for two hours, as are other foods and liquids.

After the expiration of the two-hour interval, alcohol is not taken for 24 hours for safety reasons, since its effect may adversely affect the components and the ability to absorb them.

Drug Interactions

Simultaneous therapy with ginepristone and glucocorticosteroids requires dose adjustment with increasing dosages of GCS. It is undesirable for joint use of Ginepristone with NSAIDs.

Drug compatibility with alcohol

The drug is absolutely not compatible with alcohol. Even a small amount of alcoholic beverages, which was taken on the day of drug use, can negatively affect the effectiveness.

Reviews

We picked up some reviews of women about the drug Ginepriston:

1. Margo. A normal drug, it's better than Postinor, I tried both, after Ginepristone, the cycle does not get off, no bleeding, and do not get pregnant, and a great advantage - you can drink within three days after the PA. (and Postinor only during the first day, and if he delayed this case for a couple of days, then no one will guarantee then, his efficiency is not weak). Although, of course, it is still better not to lean on such methods of contraception)) Only in the most extreme cases.
2. Natasha. I have two children, so I always try to protect myself. "Ginepriston" my aunt gave to try. She's a pharmacist in a pharmacy. Approached, I do not experience any side effects. Yes, and easy to use, do not be nervous that I forgot to take the medicine. I always forget to take a pill, then I get very nervous. Ginepriston suits me.
3. Inna. Several years ago, I took Guinepristone. Adverse reactions did not develop and effectiveness was justified. Now my baby is two years old, which proves the possibility of getting pregnant after emergency contraception.
4. Maria. I can not say that this class of drugs is rapturous, but still if you do not plan pregnancy, it's better to insure yourself in case of force majeure. Ginepriston acts delicately enough, I drank a couple of years ago, maybe a little more, I do not recall any unpleasant sensations. Now I have a half-year-old baby)) and I'm very glad that everything in life has developed exactly as I wanted and planned.

Analogues

Similar in their therapeutic effect and composition with tablets Ginepriston are the following drugs:

• Mifegin;
• Mifepristone;
• Miropristone;
• Wife;
• Pencrofton;
• Gynesril.

Before using analogues, consult your doctor.

Storage conditions and shelf life

Shelf life of the drug is not more than 3 years. Keep it in a dry, protected from light place at a temperature of 30 degrees.

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