Furacilin is a topical preparation with antibacterial and aniseptic effects.
The mechanism of action of furacilin has a specific feature that distinguishes it from other chemotherapeutic agents. In the composition of nitrofuran (the active substance of the drug) there are molecules of an aromatic nitro group analogous to chloramphenicol molecules (antibiotic levomycetin). Under their influence, amino derivatives with high reactivity are formed, capable of deforming the protein structures of microbial cells, which ultimately leads to their death.
Nitrofural is active against staphylococcal and streptococcal microflora, Escherichia coli, salmonella, clostridia, fungi of the genus Candida, viruses and some protozoan microorganisms. On the part of pathogenic microflora, resistance to the active substance of furacilin develops very slowly and does not reach a high degree.
Clinical and pharmacological group
Antibacterial and antiprotozoanoe means for external and local use.
Terms of sale from pharmacies
Can buywithout a doctor's prescription.
Price
How much does Furacilin cost in pharmacies? The average price is at the level of90 rubles.
Composition and form of release
Furacilin is available in the form of tablets of yellow color, round, flat-cylindrical. Tablets are intended for the preparation of a solution and its subsequent use for the treatment of wounds, rinsing the pharynx, rinsing the cavities.
- Each tablet of the drug Furacilin contains 20 mg or 100 mg of active ingredient Nitrofural, as well as a number of additional auxiliary components.
Tablets are packed in blisters of 10 pieces (1) in a cardboard box, a detailed instruction with a description of the characteristics is attached to the preparation.
Pharmacological effect
The active component of the Furacil tablets, which helps with infection, has an antimicrobial effect. Unlike other chemotherapeutic agents, Furacil has a different mechanism of action and forms highly reactive amino derivatives that cause conformational changes in proteins of macromolecules, which leads to cell death. Furacilin is active against most Gram-positive and Gram-negative bacteria, for example:
- Escherichia coli;
- Streptococcus spp .;
- Salmonella spp .;
- Staphylococcus spp .;
- Shigella (flexneri spp., Dysenteria spp., Boydii spp., Sonnei spp.);
- Clostridium perfringens.
Resistance to the active component of furacilin develops slowly and, as a rule, does not reach a high degree. In addition, the agent helps to increase the activity of the reticuloendothelial system and to enhance phagocytosis.
Indications for use
Indication for the use of furatsilina very diverse. In medicine, this antimicrobial agent is used to treat microbial infections of the ENT - organs and eyes, washing pleural cavities, to prevent infection and the processes of decomposition on the surface of open wounds. The main pathological conditions requiring external application of furacilin are:
- minor damage to the skin (wounds, scratches, cuts, abrasions);
- purulent wounds;
- pressure sores;
- burns and frostbite (2 and 3 degrees).
Local application of furacilin is recommended for the following diseases:
- inflammatory processes in the oral cavity (gingivitis, stomatitis);
- inflammatory lesions of the eyes (conjunctivitis, blepharitis);
- furuncles of the external auditory canal or acute otitis media (external, middle);
- osteomyelitis;
- acute tonsillitis;
- purulent-inflammatory processes in the joint or pleural cavities.
In addition, furacilin solutions are used for surface treatment before skin grafting.
Can I gargle with Thuracilin?
Gargling with Thuracilin is a good help for tonsillitis and tonsillitis. The drug, of course, does not replace antibiotic therapy and other medical measures, but it can significantly alleviate the patient's condition and accelerate recovery.
This is due to the fact that regular rinses with angina promote leaching of pathogenic microflora and pus. In addition, acting as an antiseptic, furacilin stops the growth and multiplication of bacteria. An aqueous solution of Thuracilin for gargling can be used for any type of disease, regardless of which microorganism is its causative agent.
An important property of the drug is that, when applied topically, it is almost not absorbed into the blood, so it can be apply even in young children (provided that they can gargle themselves) and in pregnant women.
Contraindications
- bleeding;
- allergic dermatoses;
- violation of the integrity of the tympanic membrane (alcohol solution);
- severe disorders of renal function (tablets);
- individual intolerance of the drug components, as well as nitrofuran derivatives.
Furacilin should be administered with caution after breastfeeding and pregnant women after assessing the benefit relationship with possible harm.
Intended use for pregnancy and lactation
During pregnancy and lactation period, you should not resort to using Furacilin for the therapy of infectious pathologies due to the possibility of penetration of nitrofural into breast milk and passage of this substance through the placental barrier.
If it is necessary to take the remedy during the lactation period, then it is mandatory to refrain from breastfeeding.
Dosage and route of administration
As indicated in the instructions for the use of Furacilin tablets are intended for the preparation of a solution. For 1 liter of hot water add 4 tablets of the drug and stir until the tablet dissolves completely. The resulting solution is cooled to body temperature and used to rinse the throat, treat the wounds and other targets according to the indications.
- To rinse the oropharynx, the solution is used up to 5 times a day, for treatment of wounds and cavities - 2-3 times a day.
The duration of the course of therapy with the drug is determined by the doctor, but usually Furacilin is used no longer than 7 days, prolonged use of the drug may cause the development of resistance of microorganisms to furacilin.
Adverse Reactions
Furacilin is tolerated very well by patients. Sometimes it can provoke such side effects as allergic reactions and dermatitis.
What happens if you drink a solution or swallow a pill?
The ingestion of a small amount of solution when rinsing the throat poses no threat to health.
Also, do not worry if you accidentally drank 1-2 tablets of the drug. There are situations when they are appointed to take inwards, therefore, in the absence of clinical manifestations of poisoning, this is also not terrible. If the taken dose is much higher than recommended, you should induce vomiting, rinse the stomach with a suspension of activated charcoal and call a doctor. Also, the affected person should be given an isotonic solution of sodium hypochlorite.
The most likely side effects of oral administration of furacilin are nausea, weakness, dizziness and vomiting. With a severe overdose, there may be dyspeptic disorders, a violation of vitamin synthesis, dysbacteriosis, hepatitis, nephritis, polyneuropathy and peripheral neuritis.
Overdose
Exceeding the permissible dose may be accompanied by:
- pain in the epigastric region;
- fever;
- dermatitis;
- dyspeptic disorders;
- allergy;
- nausea;
- hemolytic anemia;
- vomiting.
special instructions
The use of furacilin in severe burns in large areas in patients with impaired renal function can lead to progression of renal failure in the form of uremia, violations of water-electrolyte balance, metabolic acidosis.
Compatibility with other drugs
Furacilin is incompatible with procaine (novocaine), epinephrine (adrenaline), resorcinol (resorcinol), tetracaine, and other reducing agents (since it decomposes with formation painted in brown or pink color products), as well as with hydrogen peroxide, potassium permanganate and other oxidants (due to the oxidation of the drug).
Reviews
We offer you to read reviews of people who used Furacilin:
- Ira. I remember my mother as a child to rinse her throat bred Furatsilin. And now I read a lot of different reviews about his harm, that he breaks the microflora and dries his throat and destroys useful bacteria. So I stopped using it.
- Natasha. I use constantly furatsilinom for a gargling of a throat. Pain does not go away right away, but it does help. The price is also adequate. I buy in tablets and then I breed with water. In this I see its lack, as it is necessary to potter with dissolution. To store a solution, too, should not be more than a day. Side reactions did not notice from him.
- Lisa. I used to think that this is some old tool and instead of it you can buy something new and more effective for a long time. But the doctor has dissuaded me, she has registered it or him to my kid. His eyes began to turn sour and we began to wash them with a solution. All very quickly passed and now he is always in my medicine cabinet.
Analogues
Structural analogs for the active substance:
- Furatsilina alcohol solution 1: 1500;
- Furacilin tablets 0.1 g;
- Furacilin tablets for external use 0.02 g;
- Furatsilinovaya ointment , %.
Before buying an analogue, consult your doctor.
Shelf life and storage conditions
Store in a dry place, protected from light, out of reach of children, at a temperature of no higher than 25 ° C. Shelf life - 5 years.
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