DuoTrav

This is a combination drug that is designed to lower the pressure inside the eyes. Its effectiveness reaches the drug after two hours after application, after twelve hours, the greatest effect is achieved.

Pharmacological action of the drug

Travaprost and timolol are key components of these drops, they determine the key properties of the drug.

Travoprost is a highly selective agonist of prostaglandin FP receptors, it is recognized as a synthetic analog prostaglandin F2-alpha, can lower intraocular pressure, improving the outflow of watery moisture (increase uveoscleral outflow).This component of practical does not affect the reproduction of watery moisture.

Timolol is considered to be a non-selective beta-adrenergic blocker. This substance does not show sympathomimetic activity, does not have a membrane-stabilizing effect and does not have a detrimental effect on the myocardium.

With topical application, timolol lowers the intraocular pressure, because it suppresses the formation of aqueous humor, and also in small amounts activates its outflow.

Intraocular pressure decreases approximately two hours after application, the highest result can be seen after 12 hours. With a single admission of the drug, a significant reduction in blood pressure remains almost unchanged for 24 hours.

The drug has many useful properties and indications that will be useful for those people who have increased intraocular pressure.

Indications and contraindications in use

Indications

• the main focus of which is the use of this drug is the elimination of increased intraocular pressure.
• For the therapy of open-angle glaucoma.

Contraindications

• It is not recommended to use this drug for people who have hypersensitivity to the components of drops.
• You can not use this medicine for bronchial asthma (and in anamnesis), COPD, hyperreactivity of the bronchi.
• Admission is prohibited to patients with Atrioventricular blockade, chronic heart failure (in the decompensation stage), cardiogenic shock.
• In severe allergic rhinitis, too, should refrain from taking this medication.
• In corneal dystrophy.
• With individual intolerance of a group of beta-blockers.
• During pregnancy, lactation.
• Children under the age of 18 also should not use this drug categorically.

DuoTrav may appoint with reservations provided:

• Neovascular, closed-angle, narrow-angle glaucoma, pigmented or congenital glaucoma, open-angle glaucoma, which is accompanied by pseudo-phacia, pseudoexfoliation glaucoma; ophthalmic inflammatory diseases; aphakia and pseudophakia with a rupture of the posterior capsular lens, patients with a cystic macular edema, uveitis or irita.
• Beta-adrenoblockers, in particular, are prescribed with caution to people with diabetes mellitus or a tendency to hypoglycemia, because these drugs take away the symptoms of acute hypoglycemia.
• In addition, they are able to mask the signs of hyperthyroidism and provoke central and peripheral circulatory disorders, hypotension.Beta-blockers are canceled before the planned surgical interventions, since together with the general anesthesia, they are able to reduce the sensitivity of the myocardium to sympathetic stimulation, which is needed for cardiac activities.

In order for the drug to be treated in the best way and it was more effective to make sure that you have no contraindications to taking these drops.

Possible complications caused by the drug

Complications of local character

In ten percent of cases, eye irritation and conjunctival hyperemia can occur.In 1-10% of cases are possible:

• point keratitis,
• effusion into the anterior chamber of the eye,
• presence of eye pain or itching,
• photophobia,
• conjunctival hemorrhages,
• corneal erosion,
• a sense of discomfort and the presence of a foreign body,
• may reduce visual acuity, vision problems.

In addition, the patient may have a feeling of blurred vision, dry eyes, may develop allergic conjunctivitis, increased lacrimation, sometimes there is irritation in the eyelid, erythema eyelids, eyelid dermatitis, hyperpigmentation of the skin, asthenopia, darkening, thickening and lengthening of eyelashes, blepharitis.

In 0.1-1% of cases - a painful condition of the eyelids, itching and edema, allergy manifestations, edema of the conjunctiva, keratitis.

Systemic side effects

In 1-10% of cases - a sense of anxiety, the head may start to spin, taking the drug in some patients may be accompanied by headaches, it is also possible decrease or the opposite increase in blood pressure (depending on the body), bradycardia, arrhythmia, bronchospasm, urticaria, pain in the sensation in extremities.

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Dexa-Gentamicin Ointment with Instruction

Drops from glaucoma are described in this article.

Causes and treatment of lachrymation with drops http://eyesdocs.ru/zabolevaniya/slezotechenie/effektivnye-glaznye-kapli-ot-slez.html

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In 0.1-1% of cases - dyspnea, cough, irritation of the larynx, increase in the level of alanine aminotransferase and aspartate aminotransferase, contact dermatitis, a change in the color of urine, a thirst, the appearance of a syndrome postnosal edema.Possible side effects (frequency unknown) are: corneal damage, tachycardia, chest pain.

Travoprost can provoke the following symptoms: macular edema, uveitis, iritis, conjunctivitis, folliculosis conjunctiva, the appearance of crusts on the edges of the eyelids, the pigmentation of the iris can increase, bronchial asthma, exfoliation of the skin.

Timolol is able to cause:diplopia, conjunctivitis, ptosis of the century, hypoglycemia, depression, cerebrovascular disorders, cerebral ischemia, fainting, paresthesia, myasthenia gravis, cardiac arrest, arrhythmia, heart failure, atrioventricular blockade, increased heart rate, respiratory failure, nasal congestion, diarrhea, nausea, rash, alopecia, chest pain, asthenia.

This drug can cause a lot of unpleasant or dangerous complications, albeit in a very small percentage. Before you start taking these drops, it is recommended that you consult with your doctor.

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conclusions

DuoTrav-a drug that can quickly and permanently rid the person of intraocular pressure and help with open-angle glaucoma. It has many useful properties, as well as contraindications, side effects. It is released on prescription.

Also read about such drugs as Bestoksol and Betofan.