Spazmalgon

Spasmalgon is an antispasmodic and analgesic agent of combined action.

The composition of this product includes three active active ingredients: metamizole, pitofenone and fenpiverinium. The last two substances are antispasmodics - that is, they relax the smooth muscles, relieve unnecessary tension - spasm.

This medical device is often used to reduce the effects of the symptoms of pain syndromes such diseases as colic intestinal tract, diseases of the biliary tract of the excretory system and other diseases that are accompanied by spasms and painful sensations of the lower brachial girdle.

Clinical and pharmacological group

Spasmoanalgesic.

Terms of sale from pharmacies

Can buywithout a doctor's prescription.

Price

How much does Spazmalgon cost in pharmacies? The average price is at the level of150 rubles.

Composition and form of release

Spasmalgon is available in tablets and in solutions for intravenous and intramuscular administration.

• The drug contains metamizole sodium, pitofenon (spasmolytic myotropic agent) and fenpiverinia bromide (m-holinoblokator).

The composition of tablets Spazmalgona includes 500 mg + 5 mg + 100 μg of active substances, respectively. Additional elements are: gelatin, lactose monohydrate, magnesium stearate, wheat starch, sodium hydrogen carbonate, talc.

The composition of the solution includes active ingredients in the amount of:

• 500 mg + 20 μg + 2 mg;
• 1000 mg + 40 μg + 4 mg;
• 2500 mg + 100 μg + 10 mg.
• injection water.

Tablets are produced in blisters of 10, 20 and 50 pieces, packed in a cardboard box. Ampoules can be 2 ml and 5 ml, in each box there are 5 or 10 ampoules.

pharmachologic effect

Medicinal preparation Spazmalgon is an antispasmodic medication with pronounced analgesic and antipyretic properties. A wide range of pharmacological activities is due to the combined composition of the drug.

1. Pitophenone hydrochloride is a derivative of piperidine. Has myotropic spasmolytic activity. The substance has a papaverin-like effect, reducing the tone of the smooth muscles in parallel relaxing it. It provokes the elimination of painful sensations against the background of a spasm of the smooth muscle of the internal organs.
2. Metamizole sodium is a non-steroidal anti-inflammatory agent that is a derivative of pyrazolone. The substance has a pronounced anti-inflammatory, antipyretic and analgesic effect. The mechanism of action of metamizole is to inhibit the activity of both isoforms of cyclooxygenase, thereby decreasing the production of prostaglandins, thromboxane and prostacyclin.
3. Fenpiverinia bromide belongs to the group of m-holinoretseptor blockers. Also has a pronounced antispasmodic effect on the smooth muscles of the internal organs, and also reduces the degree of motility of the intestines and stomach, lowers the tone and relaxes the musculature of the bile-excreting and urinary tract.

The combination of the three active components stops pain for 15-40 minutes. Penetration by the parenteral route is faster than oral administration. The therapeutic maximum relief of pain occurs within 1-1.5 hours. The analgesic effect gradually decreases with time, completely eliminated after 6-10 hours. Its duration depends on the sensitivity of the patient, the condition of the liver.

Indications for use

Many people drink Spazmalgon's tablet with "about and without" - the stomach hurts, the heaviness in the head is felt, the muscles "ache". In fact, in the official instruction for the drug in question, there is a clear differentiation of the conditions under which Spasmalgon should be taken:

• biliary dyskinesia;
• spasm of ureters;
• colitis occurring in chronic form;
• colic colic;
• spasm of the bladder;
• condition after surgical removal of the gallbladder;
• painful menstruation.

Admission of the drug in question is also acceptable in the acute course of myalgia, ischialgia, neuralgia, arthralgia, but only as a short-term treatment. The doctor can prescribe Spasmalgon and during recovery from surgery, or after performing diagnostic procedures that are accompanied by pain.

Contraindications

If there are any of the following contraindications specified in the instructions for use, you can not use Spazmalgon:

• violations of the liver and kidneys;
• granulocytopenia;
• hypersensitivity to components derived from pyrazolone, butadiene, tribuzone;
• violation of hematopoiesis of the bone marrow;
• angina pectoris;
• chronic heart failure;
• with caution in the sensitivity to non-steroidal anti-inflammatory drugs and non-narcotic analgesics.

Intended use for pregnancy and lactation

Can I drink Spazmalgon during pregnancy? There is no information about the safe use of the drug during pregnancy, supported by serious research. Given that the components of Spasmalgon affect, including, the muscles of the pelvic organs, doctors recommend refraining from taking this drug at any time.

Likewise, it should be done during lactation. However, if Spasmalgon is not avoided, it is necessary to interrupt feeding and return to it no earlier than 48 hours after taking the last dose of the drug.

Dosage and route of administration

As indicated in the instructions for use Spasmalgon in the form of tablets are administered orally, without crushing the tablet while drinking plenty of water. According to the indications the medication can be taken in a half dose, for this it is necessary to break the tablet along the line.

The duration of treatment and dosage of Spasmalgon depends on the specific nosological unit and are determined exclusively by the physician.

1. Dosage for adults and adolescents from 15 years is usually 1-2 tablets, which are taken 2-3 times a day.
2. Dosage for children 13-15 years - 1 tablet with the same frequency of intake (no more than three tablets per day).
3. Dosage for children 9-13 years - half a tablet maximum three times a day.

Spasmalgon is not recommended for use for longer than three days. According to the indications can be appointed by a doctor in a different dosage.

Spasmalgon in ampoules

Adults and adolescents older than 15 years injected solution slowly intravenously 1 ml for a minute in a dose of 2 ml. You can repeat the injection in 6-8 hours. According to the instructions, intramuscularly inject 2-5 ml of the solution up to three times / day with a maximum daily dose of 10 ml (5 g of metamizole sodium). Treatment lasts up to five days. Before administration, the solution is warmed in the hand. Dosages for children depend on age, are 0.1-1 ml and differ by a step of 0.1 ml for every two years. Up to three months is administered only intramuscularly, after - and intravenously too.

Side effect

Because of the content of substances with a very strong analgesic effect, Spasmalgon can negatively affect the different sides of the human body:

• Allergic reactions: Quincke's edema, urticaria, rash on the skin, dermatitis, erythema, Lyell's syndrome, anaphylactic shock.
• From the nervous system: dizziness, lethargy, apathy, drowsiness, paresis, decreased sweating;
• On the part of the blood system: a decrease in the level of platelets, leukocytes, agranulocytosis;
• From the side of urinary organs: disruption of the kidneys, a decrease in daily diuresis, anuria, the appearance of protein in the urine, hematuria;
• From the side of the digestive canal: dry mouth, nausea, epigastric pain, vomiting, flatulence, constipation, pain in the right hypochondrium;
• On the part of the cardiovascular system: a decrease in blood pressure, palpitations, dyspnea, a threadlike pulse, blue limbs and nasolabial triangle.

A side effect of the injectable drug Spasmalgon is burning at the injection site, swelling of the tissues, hematoma, the formation of an infiltrate.

Overdose

Most often, an overdose of Spasmalgon occurs when it is injected into the body. Symptoms of this condition will be severe pain in the epigastric abdomen, lowering blood pressure, nausea and vomiting, increased drowsiness, convulsions.

If there is at least one of the signs of an overdose, then Spasmalgon should be discontinued. In the case of a severe overdose in a medical institution, the patient undergoes symptomatic therapy, gastric lavage.

special instructions

The use of the drug in nursing mothers requires the cessation of breastfeeding.

During the treatment with the drug, you should not take alcohol. Otherwise, the development of symptoms, characteristic of alcohol poisoning, is possible.

If the drug is used for a long time (more than a week), it is necessary to control the picture of the peripheral blood (leukocyte count) and the functional state of the liver. If suspected of agranulocytosis or in the presence of thrombocytopenia should stop taking the drug.

During treatment it is not recommended to drive vehicles and engage in potentially dangerous activities that require quick physical and mental reactions.

Interaction with other drugs

Joint reception with other medicines can cause the following consequences:

• Thiamazole - increases the risk of leukopenia.
• Other non-steroidal analgesics (painkillers) are an increase in the toxic effect.
• Antidepressants, contraceptives taken orally, - a violation of the liver.
• Chlorpromazine - the development of hypothermia, that is, a strong increase in body temperature.
• Sedative drugs, pathogens and tranquilizers - a strong, to a maximum, an increase in the analgesic effect followed by a "rollback" in the form of dry mouth, nausea and headache.

The drug "reacts" to almost every drug, excluding dietary supplements and the simplest formulations (analgin, glucose and others). So, if Spasmalgon's treatment coincides with the course of treatment with another drug, it is recommended to consult a doctor beforehand.

Reviews

We offer to familiarize with reviews of people who used the drug Spasmalgon:

1. Valera. Very good and quickly helps with tension headache. It is best to take at night, because after it pulls to sleep. The next day a good fresh head.
2. Danill. An excellent antispasmodic, especially if the pain comes suddenly. I often use spasmalgon, especially when my head hurts or when critical days start. The effect of taking the pill is visible after 10-15 minutes. Side effects for all my experience of reception did not observe. Spasmalgone can be safely called a universal remedy for spasms.
3. Ksenia. One of the best painkillers I discovered for myself. Helps with headache, with spasms in the stomach, during critical days. And most importantly, helps out with toothache. Acts quickly, just ten minutes after taking the pain back down. The price of the drug is low. You can find it in any pharmacy.

Analogues

Spazmalgon has many analogues, many of them are well known to the domestic consumer. For example, Spazmalgon's most famous analogs (synonyms) are Spazmalgin, Baralgin, Trigan, Maxigan, Spazgan. These drugs in their pharmacological action are no different from Spazmalgon.

In addition, there are a number of less well-known analogues of Spasmalgon:

• Burlon;
• I took it;
• Zolohan;
• Minalgan;
• Nebalgan;
• Piafen;
• Spazvin;
• Revalgine;
• Baralgetas;
• Nebalgan;
• Plenalgin;
• Renalgan;
• Spazvin;
• Spasmoanalgans.

Before buying an analogue, consult your doctor.

Shelf life and storage conditions

The shelf life of the drug is indicated on the package. The solution for injections should be stored in a cool dark place for no more than 2 years. If the consistency of the solution changes, precipitation or suspension in the ampoule, the drug should not be used.

Tablets can be stored at room temperature, 3 years from the date of production.

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