Tevodex is a combined preparation used locally in ophthalmology, which has an anti-inflammatory and antimicrobial effect.
This effect is due to the content of glucocorticosteroid (dexamethasone) and broad-spectrum antibiotic (toramycin). The drug is used to treat inflammatory eye diseases, as well as to prevent the development of secondary infection after surgery.
Tevendex has an antiexudative effect. With topical application, the absorption of active components is low.
Clinical and pharmacological group
Combined pharmaceutical product with antibacterial and anti-inflammatory effects.
Terms of sale from pharmacies
Can buyby prescription.
Price
How much does Tevdodex cost in pharmacies? The average price is at the level of420 rubles.
Composition and form of release
The drug is available in the following dosage forms:
- eye ointment: homogeneous, almost white or white (3.5 g in aluminum tubes with plastic screw cap, 1 tube in a cardboard bundle);
- eye drops: a suspension of almost white or white color (5 ml each in polyethylene bottles-droppers «Droptainer ™», 1 bottle in a cardboard bundle).
Active substances in the composition of 1 g of ointment and 1 ml of drops:
- tobramycin - 3 mg;
- dexamethasone - 1 mg.
Excipients of ointment: Vaseline white, paraffin liquid (mineral oil), chlorobutanol anhydrous.
Auxiliary substances of drops: sodium sulfate anhydrous, benzalkonium chloride, tyloxapol, purified water, disodium edetate, hyethelose (hydroxyethylcellulose), sodium chloride, sulfuric acid and / or sodium hydroxide.
pharmachologic effect
Tebridex is an effective drug intended for the treatment of bacterial inflammation of the organs of vision, containing in its composition a glucocorticosteroid and a broad-spectrum antibiotic. The mechanism of action is determined by the properties of these components.
Dexamethasone has an anti-allergic, anti-inflammatory and desensitizing effect, tobramycin has antimicrobial activity against a variety of gram-positive and gram-negative bacteria.
The medicine does not cause slowing of the restoration of the cornea of the eyes, therefore it is prescribed for use in the postoperative period.
Indications for use
Tevrodex is a preparation for the treatment of the following inflammatory diseases of the eyes and their appendages caused by agents that are sensitive to active substances:
- iridocyclitis;
- blepharoconjunctivitis;
- conjunctivitis;
- keratitis;
- blepharitis;
- keratoconjunctivitis.
Also, the drug is used to treat and prevent inflammatory phenomena in the postoperative period after cataract extraction.
Contraindications
Tevendex has the following contraindications:
- viral diseases of the cornea and conjunctiva (including keratitis, chicken pox and smallpox);
- removal from the layers of the cornea of the foreign body;
- tuberculosis of the eye;
- fungal lesions of the eyes;
- hypersensitivity to components;
- age to 18 years.
In addition, Tevrex should not be used during pregnancy and during breastfeeding (lactation).
Intended use for pregnancy and lactation
The drug is not recommended for use during pregnancy and during breastfeeding. In the treatment of women of childbearing age, a pregnancy should be initially excluded before conservative treatment.
Dosage and route of administration
As indicated in the instructions for use, Tevodex is applied topically (in the conjunctival sac).
Eye drops
Recommended dosage regimen: 1-2 drops every 4-6 hours.
In the first 2 days of therapy, the frequency of application can be increased (every 2 hours), then gradually, as the degree of inflammation decreases, the frequency is reduced to the standard.
In the treatment of acute severe infectious process, the following dosing regimen is shown (single dose - 1-2 drops):
- until the severity of the condition decreases: every 60 minutes;
- for 3 days: every 2 hours;
- for 5-8 days: every 4 hours.
If necessary, the course can be continued for another 5-8 days.
With a preventive purpose in the postoperative period, Tevreks is prescribed 1 drop 4 times a day. Therapy starts from the day of surgery, the course duration is 24 days. The total duration of the course does not change in cases when the use of the drug is started 1 day before the operation. If necessary, during the first 2 days after surgery, a single dose can be increased to 2 drops, the frequency of application - every 2 hours.
Before use, the vial with droplets should be shaken.
To reduce the likelihood of systemic adverse reactions (by reducing systemic absorption of the drug), after instillation of Teborex it is recommended for 1-2 minutes to easily press a finger at the inner corner of the eye into the area of the projection of lacrimal sacs.
Eye Ointment
A single dose of ointment - a strip 1.5 cm long, multiplicity of application - 3-4 times a day. As the intensity of the process decreases, the frequency of application is reduced.
Side effects
Usually the drug is well tolerated. Side effects are observed in rare cases:
- Allergic reactions: redness and swelling of the face, itching of the skin and rashes on the skin.
- Other reactions: headache, dizziness, bitter taste in the mouth, vomiting, nausea, spasm of the larynx, discharge from the nose.
- Local reactions: burning and itching, redness of the conjunctiva, sensation of foreign body in the eye, edema of the conjunctiva, dryness eye or lacrimation, inflammation of the cornea, increased intraocular pressure, reduced visual acuity. In isolated cases, cataracts, glaucoma, photophobia and mydriasis (dilated pupils) developed.
An infection caused by microorganisms that are insensitive to Tevomycin may also develop.
Overdose
With proper dosing of eye drops, Tevodex overdose develops extremely rarely. When using the drug for a long time and in large doses, signs of overdose are expressed by an increase in the side effects described above, headache, impaired vision.
In the case of an overdose of the drug, treatment is immediately stopped and sought medical help. Treatment of an overdose is symptomatic.
special instructions
In combination with the antibiotics of the aminoglycoside group, peripheral blood control is required.
In combination with other eye drops or ointments, the interval between applications should be maintained for at least 5 minutes.
The vial should be shaken before use and closed after each use. The tip of the pipette should not touch the eye.
Interaction with other drugs
In combination with systemic antibiotics of the aminoglycoside group, systemic side effects can be intensified.
Reviews
We offer to familiarize with the opinions of people who used the drug Tebrix:
- Ksenia. In winter, the child had left-sided pneumonia with exacerbation of maxillary sinusitis. A strong runny nose could not be cured by nasal drops / sprays or folk remedies. Turning to another doctor, we were prescribed a drop of tobabrace. To the child of 9 years, applied 2 drops in each nostril 3 times a day. The result pleased, after a couple of days, the edema subsided and the runny nose diminished. Now in critical cases we use the proven tool - tobabrace.
- Nastya. My child began to sour the right eye, I began to rinse it with tea, tea, then advised daisy, she also did not give her results, then decided to drip with drops, which usually the son dripped with conjunctivitis, but they did not give us the desired result. When in the morning the eyes were very strong, we went to the doctor, the ophthalmologist looked at the eye, said that the daughter has a purulent conjunctivitis and appointed us Teborox, we dripped it 1 drop 3 times a day for 5 days. The result was noticed after one day of use - in the morning the daughter woke up and pus was significantly less. After applying the medicine for three days, the pus completely disappeared and the eye was absolutely healthy. He was also assigned to the youngest son after probing the tear duct.
- Sasha. Tvorodex was appointed after the operative treatment of haljazione in a child of 3 years, dripped 4 times a day for 10 days-the child stopped eating, is capricious, cries and complains of pain in the eyes and headaches pain, became quickly tired, complains of fatigue (the child before did not know what is tired and never asked for hands, loved to walk and very much) the drug is very heavy. Children do not recommend.
Analogues
Structural analogs for the active substance:
- DexaTobrot;
- Tebronzon.
Before buying an analogue, consult your doctor.
Tebridex and Tobrex - what's the difference?
Unlike Teborex, Tobrex does not include the hormone anti-inflammatory drug Dexamethasone, but only the antibiotic Tevomycin comes in from the active ingredients.
Shelf life and storage conditions
Drops and ointment Tevodeks are among the drugs of prescription leave with a shelf life of not more than 2 years, provided that the necessary temperature storage conditions (from 8 to 27 degrees Celsius) are observed. The bottle-dropper with eye drops should be stored in an upright position.
After opening the medication can be used for a month.
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