Ambrohexal for inhalations: instructions for use

Coughing is an unconditioned reflex that occurs when irritating the respiratory mucosa.It can appear when foreign bodies, allergens, as well as viruses, bacteria and fungi enter the body. Often catarrhal disease is complicated by a cough. When infectious diseases cough cleanses the bronchi, trachea, larynx and pharynx from mucus.

Ambrohexal for inhalations contributes to faster sputum and recovery. Cough develops in two stages: first dry, then with sputum discharge. Like any other mucolytic agent, Ambrohexal is intended to treat only a wet cough caused by an infection.

On this page you will find all the information about the Ambrohexal inhalation solution: complete instructions for use on this medication medium, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already used Ambroghexal. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Conditions of leave from pharmacies

The drug is approved for use as a remedyover-the-counter vacation.

Price list

How much is the Ambrohexal solution? The average price in pharmacies is at the level of190 rubles.

Form of issue and composition

Solution for ingestion and inhalation 7.5 mg To 50 ml or 100 ml in a bottle of dark glass, equipped with a plastic dissector with a plastic screw cap and a ring of the first opening. A bottle with a measuring cup of polypropylene in a cardboard box together with instructions for use.

• 1 ml solution (about 20 drops) contains: active substance - ambroxol hydrochloride 7.5 mg;
• auxiliary substances - methylparahydro sibenzoate, propyl parahydroxybenzoate, sodium metabisulphite, citric acid, sodium hydroxide, water.

Pharmacological effect

The drug shows secretory, secretotic and expectorant properties, stimulates glandular serous cells of the bronchial mucosa, increases the amount secretion of the mucosa and the release of surfactant in the bronchi and alveoli, restores the normal ratio of mucous and serous sputum components. In addition, it reduces the viscosity of phlegm by activating hydrolyzing enzymes and increasing the yield of Clara cells by lysosomes. Increases the movement of cilia of the ciliated epithelium, accelerates mucociliary transport, thanpromotes sputum production.

Ambroxol begins to function after thirty minutes after ingestion and lasts up to six to twelve hours (according to the single dose taken). After taking the drugabsorbed quickly and almost completely. The maximum concentration of ambrohexal is determined after one to three hours. The liver undergoes its transformation, after which the metabolites (glucuronides, dibromantranilic acid) are excreted through the kidneys.

Indications for use

Ambrohexal is usually used to treat infectious diseases, which are accompanied by a prolonged cough and poor sputum discharge. Thanks to a couple with the active substance, inhalations allow directaffect the affected area. In addition, high temperatures do not allow viruses and bacteria to multiply. Thus, the action takes place from two sides. Sputum is faster, and the pathogenic microflora stops spreading and dying.

The effect of the drug can be tested in the treatment of such diseases:

• Bronchial asthma,
• Bronhoecstatic disease,
• ARI,
• Rhinitis and sinusitis in a chronic stage,
• Bronchitis,
• Cystic fibrosis,
• Pneumonia,
• Pulmonary tuberculosis.

Inhalations will helpshorten treatment time, if the procedures are performed at the first signs of the disease. Ambrohexal is not used for allergic cough, because there are no inflammatory reactions in the bronchi, an allergen acts against them, which causes irritation of the mucous membrane.

Bronchial asthma is accompanied by prolonged attacks of cough, it can appear for various reasons, it is caused by:

• Exercise stress,
• Cold air,
• Allergens,
• Infection,
• Emotional stress.

Ambrohexal is usedwith any asthma, except allergic(without infection). Inhalations are carried out with several drugs. First, use bronchodilators, then mucolytics, such as Ambroghexal, in the end - anti-inflammatory drugs.

Contraindications

Hypersensitivity to the components of the drug, pregnancy (I trimester).

With caution: The drug should be used with caution in patients with peptic ulcer of the stomach and duodenum, as there may be an exacerbation of peptic ulcer, as well as in patients with renal and hepatic insufficiency.

Application in pregnancy and lactation

Instructions for use for Ambrohexal Solution

The instructions for use indicate that adults and children over the age of 5 years are recommended to perform inhalations 1-2 times / day for 2-3 ml (40-60 drops, which corresponds to 15-45 mg ambroksola). Children under the age of 5 years are recommended to perform inhalations 1-2 times / day for 2 ml (40 drops, which corresponds to 15-30 mg ambroksola).

A solution for inhalation can be used using any modern equipment for inhalation (except for steam inhalers). The drug is mixed with saline, to achieve the optimal level of air humidification in the respirator, the drug can be diluted in a ratio of 1: 1. Since inhalation therapy can cause a deep breath to cause coughing, inhalation should be performed in the usual breathing mode.

Before inhalation it is usually recommended to warm the inhalation solution to body temperature. Patients with bronchial asthma can be recommended to carry out inhalation after taking bronchodilators.

Side effects

This drug, like many other products of the pharmaceutical industry, has a number of side effects that can occur in a certain category of patients. In the process of testing the solution for inhalation, some of the patients exhibited the following side effects, namely:

1. Allergy. Recorded such manifestations as hives on the skin, a small red rash on the chest, neck and back. There were practically no allergic reactions in the form of anaphylactic shock in medical practice.
2. Disorder of the organs of the gastrointestinal tract. There were such phenomena as nausea, diarrhea, vomiting, and lack of appetite.
3. Nervous disorders. Rarely, but still there have been cases in which the taste sensitivity of taste receptors has been compromised. Some after inhalation did not feel the mouth and throat. A few hours after the procedure was completed, the sensitivity returned.

Each organism is individual, therefore at all stages of inhalation and treatment of inflammatory diseases in the lungs, it follows that to pay attention to how the organism behaves after the active components of Ambrohexal enter the blood.

Overdose

As a rule, with an overdose of Ambrohexal there are no severe symptoms of poisoning. There was a slight disturbance from the nervous system and diarrhea. In rare cases of overdose, the patient experienced increased salivation (hypersalivation), vomiting, and lowering of blood pressure. At the first signs of an overdose, see a doctor.

If you miss a drug for inhalation, you can not take a double dose of the medicine to make up for a pass. You should continue to apply the drug according to the instructions in the usual dosage. A sudden discontinuation of Ambrohexal can cause a worsening of the patient's condition.

special instructions

With extreme caution should be used in patients with a weakened cough reflex or disturbed mucociliary transport, because in this situation, inhalations can cause sputum congestion. Also, during the treatment period, it is not recommended to perform respiratory gymnastics. Patients suffering from bronchial asthma on the background of using the drug may increase cough.

Patients with impaired tolerance to fructose before proceeding to inhalations, it is necessary to consult with the attending physician.

Data on the impact on the ability to drive vehicles and manage various mechanisms are not available.

When using the Ambrohexal solution for inhalations and antitussives, sputum accumulation in the bronchi may occur, so it is worthwhile using this combined therapy with caution.

Joint use of Ambrohexal and antibacterial agents (for example, amoxicillin) leads to an improvement in the absorption of antibiotics in the lung tissue and promotes an early recovery.

Reviews

Reviews from the use of inhalations with the drug Ambrohexal are mostly positive. The drug is successfully used to treat diseases in children. Since it is an effective mucolytic agent and relieves a strong dry cough for a week with minimal adverse reactions, except for individual intolerance to the components of the drug.

Analogues

Drops for inhalations are a rather popular form of release of medicines, since high effectiveness of inhalation therapy has been proven by many studies and practical experience of a huge number of doctors and patients.

Therefore, new drugs with mucolytic action constantly appear on the pharmaceutical market, including those based on ambroxol. It:

1. Lazolvan;
2. Ambrogen;
3. Bronhoven;
4. Flavamed and others.

Also in the pharmacy you can buy these drugs in the form of tablets, capsules, syrup with a different dosage. Often you can hear arguments: Lazolvan or Ambroheksal for inhalation what is better? But they have no scientific background, since both medicines have the same active substance, so the effect of their application will be the same.

Before using analogues, consult your doctor.

Storage conditions and shelf life

The drug in the form of a solution for ingestion and inhalation should be stored out of reach of children, protected from light at a temperature of no higher than 25 ° C. Shelf life - 4 years.

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