Fenistil gel

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Fenistil - antihistamine, antiallergic and antipruritic. The H1-histamine receptor blocker is a competitive histamine antagonist.

The drug reduces the increased permeability of capillaries, associated with allergic reactions. When applied to the skin Fenistil gel reduces itching and irritation caused by skin-allergic reactions. The drug also has a pronounced local anesthetic effect. It also has an anticoninic and weak anticholinergic effect.

With topical application, thanks to the gel base, it has a quick onset of action - in a few minutes, the maximum effect is after 1-4 h.

Clinical and pharmacological group

The drug with anti-allergic action for external use.

Terms of sale from pharmacies

Can buywithout a doctor's prescription.


How much does Fenistil gel in pharmacies cost? The average price is at the level of390 rubles.

Composition and form of release

Fenistil is available in several dosage forms: gel, drops, emulsion.

Gel Fenistil is intended for external use. The drug is available in tubes of aluminum with a volume of 30 g and 50 g in a cardboard box, an instruction with a full description of the characteristics of the drug is attached to the gel. It is a colorless transparent homogeneous substance, without any specific odor.

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  • The composition of the drug includes active active substance - Dimethindene maleate, 100 grams of gel - 100 mg.

As auxiliary components are: benzalkonium chloride, propylene glycol, carbomer, disodium edetate.

Pharmacological effect

Fenistil belongs to antihistamine preparations of the 1st generation. By blocking histamine H1 receptors, it does not allow the effects of histamine - hyperemia, increased permeability of capillaries, puffiness, itching, etc., to appear. Thus, the antiallergic and antipruritic effect of the drug is realized.

Fenistil is able to block the effects of kinins, exhibits little anticholinergic activity. Clinically, this manifests itself in the "drying" of the mucous membranes, which is sometimes used in the treatment of acute respiratory viral infections with increased secretion of the nasal mucosa. The drug has a small sedative effect, does not possess anti-emetic activity.

The gel is for topical application. It eliminates cutaneous manifestations of allergies without having systemic side effects in the form of drowsiness or anticholinergic effects. An antipruritic and light cooling effect manifests itself after a few minutes after application to the skin.

After intake quickly and completely absorbed from the digestive system, bioavailability is about 70%. It penetrates well enough into tissues. Its effect is manifested 45 minutes after admission. Fenistil is converted into the liver in metabolites, excretion occurs in the urine and bile.

Indications for use

The drug is prescribed in the case of:

  • Allergic dermatitis;
  • Atopic dermatitis;
  • Various allergic reactions to the skin (we mean only a kind of allergic disease): eczema; hives; rubella.
  • Insect bites
  • Itching of a different nature (except cholestasis);
  • Burns (only mild degree!) Solar, household, industrial.


Before starting treatment with Fenistil Gel, the doctor and patient should examine the possible consequences. The instructions for use contain a detailed list of cases when the medicinal product is prohibited. Let's consider some of them.

  1. Pregnancy (first trimester). During this period, the fetus is especially sensitive, so it is not recommended for a future mother to use any medications.
  2. It is forbidden to use the gel during lactation.
  3. For babies up to 1 month Fenistil is contraindicated.
  4. Asthma (bronchial).
  5. High sensitivity to individual components of the formulation. In this case, you need to consider an alternative option - an analog gel with the same effect.

In the presence of chronic diseases before treatment it is necessary to undergo a medical examination with the doctor, so that he can determine if the remedy will harm the body. Caution Gel or drops should be used for children under 1 year. The drug can provoke not only a sedative effect, but also a disturbance of a night's sleep, headaches. More often to small children the analogue (Vibrocilum) is appointed or nominated.

Intended use for pregnancy and lactation

Use of the drug Fenistil in the I trimester of pregnancy is possible only after consulting a doctor.

In the II and III trimesters of pregnancy and during lactation, the gel should not be used on large areas of the skin, especially in the presence of inflammation and bleeding phenomena.

Nursing mothers should not apply the drug to the nipples of the mammary glands.

Use in Pediatrics

In children from 1 month to 2 years of age, the drug should be used only after consulting a doctor.

In infants and young children, the drug should not be used on large areas of the skin, especially if inflammation or bleeding occurs.

Dosage and route of administration

As indicated in the instructions for use Fenistil gel applied to the affected area of ​​the skin with a thin layer and left until completely absorbed.

With severe itching or severe allergic reaction, the drug Fenistil in the form of a gel is recommended to combine with oral forms of the same agent, for example, with drops.

The gel is applied 2-4 times a day, the duration of treatment with the drug is determined by the doctor individually, but usually is no longer than 5-7 days. If during this period allergy manifestations did not decrease or, on the contrary, worsen, the patient should repeatedly consult a doctor to correct the prescribed therapy and clarify the diagnosis.

Adverse Reactions

When applied to the skin, no more than 10% of the active substance enters the blood, so pobochki are extremely unlikely. Nevertheless, the official list is as follows:

Headaches, dizziness, dysfunction of external respiration, swelling, increased excitability, drowsiness, muscle spasm, dry mouth, skin rash, nausea.


When taking the drug orally, the dosage indicated in the instructions should be strictly observed, since there is a risk of overdose. In this case, depression of the central nervous system may develop, drowsiness (in adults), stimulation of the central nervous system and m-cholinoblocking manifestations (more often in children), among which are tachycardia, agitation, ataxia, convulsions, hallucinations, mydriasis, dry mouth, fever, flushing, urinary retention, lowering of blood pressure, collapse.

If an overdose of Fenistil occurs, the patient is assigned activated charcoal, and a salt laxative is also shown. In the process of treatment, it is necessary to take measures to support the functions of the respiratory and cardiovascular systems.

Cases of overdose of external forms of the drug are not described. If the drug accidentally gets inside, it is necessary to take similar measures. There is no specific antidote.

special instructions

Before you start using the drug, read the special instructions:

  1. The drug is ineffective when itching, associated with cholestasis.
  2. When using the drug Fenistil on large areas of the skin should avoid exposure to sunlight.
  3. If the itching is severe or if extensive areas of the skin are affected, the drug can be used only after consulting a doctor.
  4. If during the period of application of the drug Fenistil the severity of the symptoms of the disease does not decrease or intensifies, consultation of the doctor is necessary.
  5. The drug contains propylene glycol and benzalkonium chloride. The emulsion also contains butylhydroxytoluene. The listed excipients can cause local allergic reactions (contact dermatitis). Butylhydroxytoluene can also cause irritation of the eyes and mucous membranes.

Compatibility with other drugs

Fenistil enhances the action of anxiolytics and hypnotics.

With simultaneous administration with Fenistil ethanol (alcohol) there is a slowing down of the rate of psychomotor reactions.

MAO inhibitors increase the anticholinergic and inhibitory effect on the central nervous system.

Tricyclic antidepressants and m-holinoblokatory increase the risk of increased intraocular pressure.


We offer you to familiarize yourself with the reviews of people using Fenistil gel:

  1. Victoria. The child constantly has redness on the skin, mosquitoes bite hard huge red blisters. Recently learned that the newborn after a month can smear the skin red with Fenistil cream. The drug is nonhormonal, so it can not harm the child. I tried and now I constantly use only this ointment.
  2. Galina. At me ointment Fenistilum - the universal agent for all unpleasant cases. I use immediately after thermal burns at home, after application, blisters do not occur. Successfully relieves redness and discomfort after exposure to sunlight. I learned that you can use mosquito bites. Need to try.
  3. Elena. Good for insect bites. In our family, everyone reacts to mosquito bites hard, with severe itching and redness. You shave with fenistil - everything goes away quickly. We use emulsion and gel, too.

Parents often speak about Fenistyle for children positively - in about 85% of cases. This is due to the rapid action of the drug, which literally within a few hours is able to remove allergic-like symptoms that bother the child. And the drop is very popular in the fight against allergy, and the gel is used to eliminate the effects of insect bites. Many children strongly comb the places of mosquito bites, itching does not allow them to sleep and creates a feeling of severe discomfort. The gel perfectly removes the itching, eliminates swelling and redness, returning the child a normal state.

Negative reviews about Fenistyle for children are associated with his strong sleeping pills and the severity of side effects in the form of burning skin. In this situation, the drug eliminates allergy symptoms, but the severity of the side effect exceeds the benefit, so Fenistil is given a general negative evaluation. After all, the drowsiness of the child makes the parents strongly worry, looking forward to the end of the drug. A burning sensation of the skin brings the child no less discomfort than the itching.


Structural analogs for the active substance:

  • Vectavir.

Before buying an analogue, consult your doctor.

Shelf life and storage conditions

Shelf life - 3 years, production date is indicated on the package. Store the drug at a temperature of no higher than 25 ° C, in a place inaccessible to children and in the original packaging.

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