How to take Wigantol: instructions and reviews

Vigantol is among the vitamin-like substances that improve intracellular metabolism and the processes occurring in them.

The effect of the drug is directed to improved capture of calcium and phosphorus ions and a reduction in their loss. Ions are necessary for the normal construction of bone tissue.

On this page you will find all information about Vigantol: the full instruction on the application for this medicine, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already used Wigantol. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

The drug regulates the exchange of calcium and phosphorus.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much does Wigantol cost? The average price in pharmacies is at the level of220 rubles.

Form of issue and composition

The drug is available in 10 ml vials in the form of an oily solution, without taste, odor and color. In one milliliter about 30 drops. At first glance, the volume seems small, but it is sufficient for long-term use in the treatment of young children.

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Composition - in 1 ml contains:

the main substance cholecalciferol - 0.5 mg, this corresponds to 667 IU * vitamin D3;
additional substances - triglycerides - 939.5 mg.

ME (international units) - indicate the amount of active substance in the preparation. In 1 IU of vitamin D3, 0.025 μg of cholecalciferol.

Pharmacological effect

Колекальциферол replenishes stocks of vitamin D3, promotes strengthening of a suction of a calcium, reabsorption of phosphates. The drug enhances the mineralization processes in the bones, provides normal functions of parathyroid glands. Kolekaltsiferol increases the over-membrane movement of calcium, divalent cations into the cell, mitochondria.

Indications for use

What helps Wigantol? The drug is prescribed for such diseases:

Hypocalcemia.
Hypocalcemic tetany.
Treatment of osteoporosis (of various origins).
Treatment of osteomalacia (against the background of violations of mineral metabolism in patients older than 45 years, prolonged immobilization in case of injuries, compliance with diets with refusal to accept milk and dairy products).
Prophylaxis and treatment of rickets.
Prevention of vitamin D deficiency in high-risk groups (malabsorption, chronic small bowel disease, biliary cirrhosis, conditions after resection of the stomach and / or small intestine).
Treatment of hypoparathyroidism and pseudohypoparathyroidism.

Contraindications

Wigantol drops can not be taken if observed:

hypervitaminosis D;
the presence of calcium stones in the genito-urinary organs;
individual intolerance to the composition of the drug;
elevated levels of calcium in the blood and urine;
hyperthyroidism (because of the risk of hypersensitivity);
Renal osteodystrophy, which is accompanied by an elevated level of phosphorus in the blood.

With caution, the drug costs if the patient is observed:

the deposition of phosphate stones in the genitourinary organs (including in the anamnesis);
organic heart disease;
acute and chronic pathologies of the kidneys and liver;
atherosclerosis;
heart and kidney failure;
sarcoidosis and other granulomatosis;
elevated levels of phosphorus in the blood;
diseases of the digestive system (including stomach ulcers and 12 duodenal ulcers);
hypothyroidism;
parallel reception of other medicines containing vitamin D3.

Application in pregnancy and lactation

Wigantol should be used with caution in pregnancy and during lactation (breastfeeding).

During pregnancy and during breastfeeding, adequate intake of vitamin D3 is required.
In case of overdose, hypercalcemia and transplacental penetration of vitamin D3 metabolites into the fetus may occur, which can lead to a teratogenic effect: retardation of mental and physical development of the fetus, special forms of aortic stenosis.

Vitamin D3 and its metabolites are excreted in breast milk.

Instructions for use

The instructions for use indicate that Wiganthol is ingested with milk or other liquid.

Supportive therapy of osteoporosis: 2-5 drops (about 1334-3335 ME vitamin D3) / day.
Treatment of rickets: appoint 2-8 drops (about 1334-5336 ME vitamin D3) / day. Treatment should be continued for 1 year.
Prophylaxis of rickets: full-term healthy children Vigantol is prescribed from 2 weeks of life for 1 drop (about 667 IU of vitamin D3) daily. Premature babies are prescribed from 2 weeks of life 2 drops (1334 ME vitamin D3) daily. The drug should be taken during the first and second years of life, especially in the winter months.
Prevention of vitamin D3 deficiency in malabsorption syndrome: 5-8 drops (about 3335-5336 ME vitamin D3) / day.
Prevention of the risk of diseases associated with vitamin D3 deficiency: 1-2 drops (about 667-1334 IU vitamin D3) / day.
Treatment of osteomalacia caused by vitamin D3 deficiency: 2-8 drops (about 1334-5336 ME vitamin D3) / day. Treatment should be continued for 1 year.
Treatment of hypoparathyroidism and pseudohypoparathyroidism: depending on the plasma concentration of calcium, 15-30 drops (about 10 005-20 010 IU of vitamin D3) are prescribed per day. The concentration of calcium in the blood should be checked for 4-6 weeks, then every 3-6 months, and adjust the dose according to the calcium content in the blood.

Side effects

The use of Vigantol can cause the following side effects:

Allergic reactions: itching, rash, hives.
From the musculoskeletal system: myalgia, arthralgia.
From the side of the cardiovascular system: increased blood pressure, arrhythmia.
From the digestive system: constipation, flatulence, nausea, abdominal pain, diarrhea, decreased appetite.
From the side of metabolism: hypercalcemia and hypercalciuria in case of taking the drug for a long time in high doses, polyuria.

Other: headache, impaired renal function, exacerbation of the tuberculous process in the lungs.

Overdose

If the recommended therapeutic dose is significantly exceeded, the symptomatology of hypercalcemia develops, which consists in the appearance of nausea, vomiting, violation rhythm and frequency of cardiac activity, changes in consciousness, up to its loss, hallucinations, anorexia (lack of appetite), increased blood pressure. From the kidneys may develop polyuria.

For the treatment of overdosage, the stomach, intestines are washed, laxatives and intestinal sorbents are used. To reduce the level of calcium in the blood, intravenous drip infusion of saline and the use of furosemide (a diuretic that promotes the excretion of calcium salts with urine).

special instructions

If you need to take the drug during pregnancy requires careful selection of the dose. It is due to the fact that overdose may develop hypercalcemia and transplacental penetration of vitamin metabolites D3 in the fetus, and this can lead to a delay in physical and mental development, special forms of aortic stenosis.

In addition, it is important to consider that vitamin D3 and its metabolites are excreted with the mother's milk, so caution is also needed when using Vigantola during lactation.

Drug Interactions

When applying Wigantola, it is necessary to take into account that:

Increased risk of hypercalcemia occurs with simultaneous use with benzodiazepine derivatives;
Primidone, phenytoin and barbiturate drugs increase the need for vitamin D3;
The toxic potential increases when combined with cardiac glycosides;
Assimilation of vitamin D3 is reduced when combined with calcitonin, colestyramine, colestipol and bisphosphonates;
Long-term treatment with antacids containing aluminum and magnesium ions promotes their increase concentration in the blood and the risk of intoxication (especially in the background of chronic renal failure).

Observe the interval between the medications you need:

With sodium fluoride - not less than 2 hours;
With oral forms of tetracyclines - not less than 3 hours.

The effectiveness of Vigantola is not dependent on food intake. Combine the use of drops with analogues and metabolites of vitamin D can be only in exceptional cases, while controlling the level of calcium in the blood serum.

Reviews

We picked up some feedback from people about the drug Wigantol:

Marina. Like many, my child had problems with the digestibility of vitamin D. The child complained of pain in the joints, weakness. At the reception the doctor said that this is a seasonal vitamin deficiency and to strengthen the bones you need to drink vitamins. Recommended drops "Vigantol". Literally a week later, the results became visible - the child stopped complaining about joints and became more alert and moving. In general, I recommend it to everyone!
Pauline. Reception vigantola to me has appointed or nominated the endocrinologist because of infringement in job parathyroid gland, after passage of a course of treatment by these drops I have made the analysis of a blood on calcium, the indicator came back to normal, and I already felt it, since the chips of the enamel on the teeth became smooth, and not rough, as before the reception of the vigantola.
Ivan. The baby is very allergic since birth. In three months they were lying in the hospital in an allergic department, there was no live place on the baby, although my mother was on a diet, or almost nothing at all. We were treated with antihistamine, hormonal and non-hormonal ointments, there were no improvements. From three months they switched to an amino acid mixture, which also did not help. We have completely dropped our hands, the doctors could not help. In one of the programs Dr. Komarovsky heard a recommendation on the intake of vitamin D, for children with atopic dermatitis. After reading the reviews, chose "Wigantol". Drank 1-2 drops a day with calcium. Allergic rashes began to pass before the eyes, introduced a complement. Now pours out very rarely and very little.

Analogues

Synonyms of the drug, in which the active substance is used kolokaltsiferol: Akvadetrim and Vitamin D3.

Analogues of Wigantol are such medicines, as:

A.T. 10;
Ethalph;
Alpha D3-Teva;
Osteotriol;
Alfadol-Ca;
Alfadol;
Rockaltrol;
Videchol.

Before using analogues, consult your doctor.

Storage conditions and shelf life

According to the manufacturer's recommendations, it should be stored at a temperature of 15-25 ºС in a place protected from sunlight. If these recommendations are complied with, the shelf life of the drops is 5 years.