Kombilipen: instruction on the use of injections and pills

What helps Kombilipen. Instructions for the use of injections and pills

A modern pharmacological agent, a combined multivitamin formulation - tablets and injections "Kombilipen".

What helps the medicine? The drug has proven itself in the practice of specialists in the management of patients with various pathologies of the musculoskeletal, as well as neurological system.

Medication "Kombilipen" instructions for use suggest use with neuralgia, intervertebral hernia, osteochondrosis.

In what form is the

To date, the medicine Kombilipen, the instruction for use reports this, is presented in two main forms:

• solution for the intramuscular route of administration - in ampoules of transparent glass with a volume of 2 ml, in a package of 5 or 10 pcs., 30 pcs .;
• rounded, covered with a protective shell biconvex tablets - packing in the cells of 15 and 30 pieces, or 45 and 60 pcs.

The optimal way to administer a medicine inside a human body should be determined by a specialist.

Main cast

Based on the instructions attached to the pharmacological agent, in 1 ml of the Kombilipen complex there are:

• 50 g of thiamine hydrochloride and the same amount of pyridoxine hydrochloride;
• cyanocobalamin 500 μg;
• lidocaine - 10 mg.

Of the auxiliary components are listed: potassium hexacyanoferrate and sodium hydroxide, benzyl alcohol and sodium tripolyphosphate, as well as water.

In 1 tablet of the drug, the following components are available:

• 100 mg of benfotiamine and the same amount of pyridoxine hydrochloride;
• cyanocobalamin - 2 mcg.

Auxiliary components:

• calcium stearate;
• microcritical pulp;
• carmellose sodium;
• povidone;
• tal and polysorbate;
• sucrose.

This combination of substances allows the drug to best provide pharmacological effects.

Healing properties

The pharmacological orientation of the drug "Kombilipen from which it helps with neuritis, is determined by the characteristics of the substances present in its composition.

For example, Thiamine hydrochloride is able to take an active part in the full conduct of the impulse along the nerve fiber.

A similar action is possessed by Benfotiamine, a fat-soluble variant of all the same vitamin B1.

It is necessary for the human body for the course of physiologically correct hematopoiesis, for the full functioning of CNS structures.

It is also ensured the provision of synaptic transmission and participation in the processes of inhibition in the cerebral cortex of the transportation of sphingosine present in the nerve fiber membrane. There is participation in the release of catecholamines.

The most important factor for complete growth, as well as hematopoiesis and the formation of epithelial cells, is Cyanocoblamin. It is also necessary for the synthesis of nucleotides and myelin, the metabolism of B9.

Tablets, injections "Kombilipen what helps the medicine, and when appoint

The manufacturer lists the following negative conditions in the accompanying package containing the medicine, under which the medicine can really help:

• neuralgia of the branches of the trigeminal nerve;
• inflammatory lesion of the facial nerve;
• polyneuropathy - a different nature of formation.

What are the "Kombilipen" injections helping from yet? Indications include pain syndrome in people suffering from pathologies associated with degenerative lesions of the spine - for example, intercostal neuralgia, cervico-brachial syndrome, radicular syndrome.

Experience in the use of medicines by specialists of various profiles indicates a high effectiveness of the drug in complex therapy.

Basic and relative contraindications

As with any medication, the multivitamin complex "Kombilipen" has a certain number of contraindications:

• decompensated pathology of the cardiovascular system;
• period of pregnancy and subsequent lactation of the baby;
• individual hyper-reaction to active and auxiliary drugs "Kombilipen from which injections and pills can cause allergies;
• children's category of patients up to 15-18 years and teenagers.

If one or more of the above contraindications is detected, the specialist will select another drug with a similar mechanism of pharmacological action.

The drug "Kombilipen instructions for use

Injections

At the expressed negative symptomatics the injection way of conducting a solution of the vitamin complex is carried out daily, on 2 ml in a thickness of muscular weight. The length of the treatment course is about 5-7 days. Then the therapy can be continued, but already 2-3 times a week, no more than 2.5-3 weeks.

With moderate pain syndrome, parenteral administration of the vitamin solution is carried out 2-3 times per week, but not more than 8-10 days. The dosage is adjusted by a specialist.

How to drink tablets

The oral route of administration involves taking "Kombilipen" tablets after meals, accompanying with a small amount of water, crumbling or chewing is not required. Dose for adult patients up to 1-3 pcs / day.

The duration of the treatment course is determined by the attending physician - based on the severity of the symptoms, the age category of the patient, his initial state of health. However, the period of 3.5-4 weeks should not be exceeded.

Side effects

In most cases, the drug "Kombilipen" is well tolerated, but in rare cases, there may be side effects:

• dermatitisation for example, urticaria;
• difficulty breathing;
• angioedema;
• hyperhidrosis;
• heartbeat over 100 per minute;
• acne eruptions.

After the abolition of the drug, all of the above negative effects are eliminated on their own.

Analogues of the drug Kombilipen

Similar multivitamin composition has analogues:

1. "Polite for children."
2. "Heptavit."
3. Vectrum junior.
4. «Antioxidants».
5. "Milgamma."
6. Benfolipen.
7. Pikovit forte.
8. "Multivita plus."
9. "Stress Formula 600".
10. "Polybion."
11. "Pentovit."
12. "Vibovit."
13. "Angiovit."
14. Neurotrate forte.
15. "Multivitamin mixture."
16. "Undevit."
17. Vitatcitrol.
18. "Triovit Cardio".
19. "Stresstabs 500".
20. Revit.
21. Rikavit.
22. "Aerovit".
23. Beviplex.
24. "Tetravit."
25. "Gendevit."
26. "Vitamult".
27. Alvitil.
28. "Vitasharm".
29. Pregnawit F.
30. The Vetoron.
31. "Believe Baby".
32. Neuromultivit.
33. "Baby Jungle".
34. "Vitabeks".
35. "Hexavit."
36. «Decamevit».
37. "Neurogamma."
38. "Trigamma."
39. "Compliments".
40. "Foliber".
41. "Pikovit."
42. «Multi-tabs».
43. Sana-Sol.
44. Unigamma.
45. "Jungle".
46. "Calcevita".
47. "Macrovit."

Which is better: "Milgamma" or "Kombilipen"?

Both drugs include the same B vitamins and have the same effect. However, "Milgamma" is a more expensive analogue.

Price

Injection solution Kombilipen in Moscow can be bought for 240 rubles. This price is 10 injections. Tablets cost 260 rubles (30 pieces). In Kiev, the medicine is sold for 200 hryvnia, in Kazakhstan - 1175 tenge. In Minsk, pharmacies offer to buy an analogue of "Milgamma."

Reviews

The majority of patients and the specialist noted the high effectiveness of the drug "Kombilipen" - in the complex treatment of a variety of neurological pathologies.

There is also a democratic cost of the drug, and the presence of lidocaine in it, which reduces severity of pain when the solution is injected into the muscle, in comparison with similar drugs subgroup B.

A few negative reviews about the drug, it is understandable individual hyperreaction to the components of the drug, or by its incorrect application.

A source: http://OtchegoPomogaet.ru/kombilipen-instrukciya-po-primeneniyu.html

Kombilipen injections and pills: instructions for use, analogues

Kombilipen is a multivitamin drug of the new generation, which effectively fights with various inflammatory processes in the body.

Its composition includes many groups of vitamins, including vitamins of group B. Moreover, the medicine contains an effective analgesic substance - lidocaine.

All components of the drug favorably affect the metabolic processes in the body and contribute to a better conduct of nerve impulses.

Also, the drug Kombilipen provides nerve cells with the necessary glucose. Because of its lack in the body, cells can deform, increase in growth, which leads to various violations of their basic functions.

Pyridoxine hydrochloride or vitamin B6 takes a direct part in the metabolism of the entire central nervous system.

He is responsible for the correct conduct of the nerve impulse in the muscle tissues, stimulates the processes of inhibition and excitation of the nervous system, takes part in the synthesis of adrenaline and noradrenaline.

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In this case, vitamin B6 transports a component of the nerve shell - the substance of sphingosine.

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Vitamin B12 is involved in the formation of choline, which is necessary for the synthesis of a neurotransmitter - acetylcholine.

It helps in the synthesis of nucleic acids and folic acid, increases the regeneration of tissue.

In this case, vitamin B12 effectively helps in the formation of red blood cells in the blood and strengthens their resistance to various negative factors.

Kombilipen injections and tablets - pharmacological properties

The action of this medication details the instructions for the use of Kombilipen.Neurotropic substances of the drug provide normal hematopoiesis and the functioning of the peripheral and central nervous systems.

Vitamin B6 is a vital substance for the metabolism of proteins, fats and carbohydrates in the human body. Pyridoxine hydrochloride (vitamin B6) is necessary for the normalization of various processes in the body, the synthesis of many biological substances and various amino acids.

Vitamin B12 is essential for the growth of epithelial cells. It synthesizes myelin and nucleotides, it is biologically active in the process of hematopoiesis. Cyanocobalamin is an indispensable substance for the metabolism of folic acid in the human body.

This vitamin is involved in many biosynthetic reactions, activates the immune system, produces the desired myelin. B12 also has a small analgesic effect and increases the resistance of cells to oxygen starvation.

The composition of this drug also includes vitamin B1, which provides the best conduct of nerve impulses.

Thiamine affects the metabolism of fats and carbohydrates in the human body, takes a direct part in the blood and has a positive effect on the entire central nervous system.

Vitamin B1 actively protects the body from various negative external factors.

Anesthetizing effect has lidocaine, which is part of the medicinal product.

Lidocaine causes the blockade of sodium channels and prevents painful impulses along the nerve fiber.

This drug also effectively stimulates the gastrointestinal tract. Its propulsive motor activity is enhanced by the action of many active substances as a result of antagonism with some receptors.

As a result, acetylcholine is released, its destruction in the body is suppressed, and the activity of acetylcholinesterase increases.

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The drug specifically affects the upper sections of the gastrointestinal tract, speeding up metabolic processes in the intestine and stomach.

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As a result of interaction with D2-receptors, this drug produces a slight antiemetic effect. It causes suppression of the vomiting reflex.

Benefits

1. Scientifically proven that this drug effectively inhibits the aging process in the human body. Vitamins of group B allow to prolong full-fledged life in elderly and senile age, strengthening the whole organism.

   At the same time, their main action is aimed at improving mental processes and strengthening the activity of the brain.

2. B vitamins are also indispensable in coordinating the activity of the central nervous system.

   They coordinate the passage of nerve impulses in the muscle tissues and have a direct effect on the mediators. This drug is an active mixture of several vitamins.

   It is designed for effective and efficient treatment of various diseases of the central nervous system. Scientifically proven the effect of this drug on the work of muscles and brain.

3. Kombilipen improves the state of the body with a variety of diseases of the musculoskeletal apparatus, spine diseases, and also effectively restores the body after surgery interventions.

   It has been scientifically proven that treatment with the drug improves intelligence by fifteen points. Providing all possible support to the whole organism, this medicine copes with many diseases of a person in old age.

Indications for use

Kombilipen is indicated for the treatment of various neurological diseases.

As part of complex therapy, this drug is used for neuralgia of the trigeminal nerve.

The drug is also prescribed if the patient has a pain syndrome caused by certain diseases of the spine.

The main indications for use:

• neuritis of the facial nerve;
• polyneuropathy;
• neuralgia of the trigeminal nerve;
• lumbar syndrome;
• pathological changes of the spine;
• intercostal neuralgia;
• diseases of the musculoskeletal system;
• diseases of the spine;
• vitamin B vitamins;
• rehabilitation recovery of the body after surgery.

Dosage forms of the drug

Kombilipen is available in tablets and in solution for injection. Ampoules with a solution are intended for intramuscular injection. The drug Kombilipen tabs is available in tablets that are coated.

Scheme of reception of Kombilipen - instructions for use

Ampoules

The solution for injections is administered intramuscularly. Usually the drug is prescribed for two milliliters per day for 5-7 days. After the drug is prescribed for two milliliters two or three times a week. In mild cases of the disease, the drug is prescribed twice a week for two milliliters.

The course of treatment is determined individually by the attending physician, taking into account the characteristics of the patient's body and the immediate symptoms of the disease. As a supporting drug therapy, simultaneous intake of B vitamins for oral administration is recommended.

The injection includes additional substances such as potassium salts and sodium phosphates. The solution for injections has a ruby ​​color and a characteristic odor. Lidocaine provides effective local anesthesia during injection.

Tablets - instructions for use

The tablet of the drug should be swallowed whole, washed down with a small amount of water. Do not grind the tablet. Eating does not affect the pharmacological effects of the drug.

For adults, this medication is prescribed one tablet from one to three times a day. The duration of treatment with tablets is determined by the attending physician. It is not recommended the duration of therapy with the drug for more than one month.

Side Effects and Actions

Like any medicine, Kombilipen can cause minor side effects. When treating this medication, allergic reactions can occur, the appearance of acne.

In some cases, patients develop hives, itching, and slight sweating. From the side of the cardiovascular system, tachycardia and shortness of breath can occur.

In rare cases, patients develop anaphylactic shock.

If any side effects occur, consult a doctor who can reduce the dose of the medicine or cancel the drug. It is possible to replace the drug with similar medicines similar in pharmacological properties to Kombilipen.

The main side effects are:

• itching of the skin;
• hyperhidrosis;
• allergy;
• angioedema;
• tachycardia.

Contraindications

This drug has a small number of contraindications. The drug is prohibited to be used in the treatment of various diseases with its individual intolerance to the patient. It is also not recommended to take the medication for pregnant women and breastfeeding women.

Kombilipen during pregnancy and lactation

The effect of the drug Kombilipen was not studied in pregnant women.

At the same time, any intake of various drugs during fetal gestation may adversely affect the health of the future child.

Doctors do not recommend using the drug Kombilipen during pregnancy. The use of this drug may cause the future child to develop various pathologies and defects of the body's systems.

The use of Kombilipen in a state of pregnancy can only be shown for vital reasons. In this case, drug therapy with the drug should be carried out with strict medical control over the state of health of the pregnant woman.

Also, the drug is not recommended for use in the treatment of lactating women. During breastfeeding the child is required to refuse treatment with this medication or to transfer the child to artificial feeding.

Special instructions for use

This medicine has an effective restorative effect on the entire body of the patient. However, with special care this medication is prescribed for patients who have congenital physiological defects of the cardiovascular system.

The drug is contraindicated in children in infancy, because it contains benzyl alcohol in its composition. Children over 12 years of age can be prescribed a drug only under the supervision of a doctor.

Components of the drug come into direct interaction with certain groups of drugs. Do not take Kombilipen with phenobarbiturates, penicillins, methylsulfides and riboflavin.

When using Kombilipen in the treatment of the disease it is forbidden to take alcohol, as it reduces the effect of the drug and inhibits further absorption of B vitamins.

Analogues

There are certain drugs that are effective analogues of Kombilipen.

All of them are similar to the given medicament on the pharmacological properties and medical action in the human body.

Each of the medicines listed below has its own value, different from the price of Kombilipen.

Analogues:

1. Kombigamma;
2. Vitaxon;
3. Neurolec;
4. Neurorubine;
5. Milgamma;
6. Neurobion.

The drug Kombilipen has special advantages over its counterparts. It has a lower cost, and is also more effective in treating various diseases. For example, Neurobion is less effective compared to Kombilipen according to the famous scale of Vyshkovsky.

Kombilipen is a complex vitamin remedy, which has a beneficial effect on the entire human body.

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It is able to lower the level of cholesterol in the blood of a person, contributes to the improvement of various metabolic processes in the patient's body, improves the overall health.

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The active substances that make up the drug, promote the expansion of blood vessels, correct the level of sex hormones in the body, increase immunity and normalize the arterial pressure.

Price

The drug can be purchased at domestic pharmacies at an affordable price. Its immediate value varies in a different price range.

The approximate price of the medication is from 120 to 200 rubles. At some points of sale, the cost of injection solution can be quite low.

Feedback on treatment

Review No. 1

Maria, 65 years old - St. Petersburg

Reference No. 2

Grigory, 58 years old - Moscow

Review No. 3

Ekaterina, 45 years old - Samara

Ok.ruMailru Skype

A source: https://glavvrach.com/kombilipen-ukoly-tabletki-instrukci/

What helps from Kombilipen? Instructions for use

Combined vitamin medication is Kombilipen. What helps with this drug? The agent has an effect on metabolic processes, normalizes hematopoiesis. Komplipen instructions for use prescribe to take with neuralgia, pain in the back.

Composition and form of release

The drug is released as a solution for injections and tablets. The drug in the form of a solution is contained in ampoules of 2 ml, the package includes 5, 10 and 30 ampoules.

Tablets Kombilipen Tubs round, covered with a film white shell, biconvex.

They are sold in cell packs of 15, 30, 45 or 60 pieces in cardboard boxes.

The composition of 1 tablet of the drug is: pyridoxine hydrochloride - 100 mg, benfotiamine - 100 mg, cyanocobalamin - 2 μg. As auxiliary substances: carmellose sodium, microcrystalline cellulose, povidone K30, calcium stearate, talc, polysorbate, sucrose.

pharmachologic effect

The effect of the drug Kombilipen, which helps with pain in the spine, is determined by the properties of the vitamins that make up its composition:

• Thiamine hydrochloride (vitamin B1) is involved in conducting a nerve impulse.
• Pyridoxine hydrochloride (vitamin B6) has a vital effect on the metabolism of proteins, carbohydrates and fats, is necessary for normal hematopoiesis, the functioning of the central nervous system and peripheral nervous system. It provides synaptic transmission, inhibition processes in the central nervous system, participates in the transport of sphingosine, which is part of the nerve shell, is involved in the synthesis of catecholamines.
• Cyanocobalamin (vitamin B12) is involved in the synthesis of nucleotides, is an important factor in normal growth, hemopoiesis and development of epithelial cells; is necessary for the metabolism of folic acid and synthesis myelin.

Medicine Kombilipen: what helps

Indications for use include the following neurological pathologies:

• trigeminal neuralgia;
• polyneuropathy of different origin (alcoholic, diabetic);
• inflammation of the facial nerve;
• pain syndrome in diseases of the spine (lumbar syndrome, intercostal neuralgia, cervico-brachial syndrome, cervical syndrome, lumboschialgia, radicular syndrome, as a result of pathological changes spine).

Contraindications

The drug Kombilipen instructions for use prohibits taking with:

• cardiovascular insufficiency;
• intolerance of components of injections and tablets Kombilipen, from which allergic reactions can be observed;
• pregnancy and breastfeeding.

Vitamin Kombilipen: instructions for use

Injections

The solution is intended for intramuscular administration.

If symptoms of the disease are pronounced, injections are carried out for 5-7 days to 2 ml daily, after which the introduction of Kombilipen is continued 2-3 times a week for another two weeks.

With a mild form of the disease, injections are carried out 2-3 times a week for no more than 10 days. Treatment with Kombilipen solution is carried out no more than two weeks, the dosage is adjusted by the attending physician.

Instructions for the use of tablets

Take the drug Kombilipen Tubs you need after eating, drink a small amount of water, do not chew. Adult patients take 1-3 tablets daily. The course of treatment is appointed by a specialist. Take high doses of the drug can not last longer than four weeks.

Adverse Events

The medicine can cause the following side reactions:

• allergies (urticaria, niononeurotic edema, anaphylactic shock, skin itching);
• hyperhidrosis;
• acne;
• tachycardia.

Interaction and special instructions

If the pill or injections of Kombilipen is combined with the drug Levodopa, there is a decrease in the effect on the body of vitamin B6.

You can not combine injections with those substances that have redox effect, since they are incompatible with vitamin B1.

It is mercury chloride, carbonate, iodide, acetate, tannic acid.

In addition, thiamine can not be combined with sodium phenobarbital, riboflavin, metabisulphite, benzylpenipple, dextrose. Thiamine breaks down very quickly, in contact with copper.

Also, thiamine is inactivated when the pH exceeds 3. Vitamin B12 is not combined with heavy metal compounds. Kombilipen contains benzyl alcohol, so it can not be administered to children.

Analogues

The following drugs have a similar effect:

• Macrovite.
• Tetravit.
• Decemevit.
• Aerovit.
• Multi-tabs.
• Undevit.
• Hexavite.
• Revit.
• Vitasharm.
• Pikovit.
• Omega 3.
• Pikovitz Forte or Vetoron.

Pharmacies are analogous to Kombilipen, which contain similar active ingredients. When choosing an analogue, you should consider what Kombilipen is, and what vitamins are included in its composition.

Price, where to buy

In Russia, you can buy Kublipen injections for 138, tablets - 109 rubles. In Ukraine, the cost is 260 - 400 hryvnia, depending on the number of tablets. It is difficult to buy a medicine in Belarus and Kazakhstan.

Opinions of patients and doctors

Reviews for Kombilipen are mostly positive. Patients note its beneficial effect in the complex treatment of various neurological diseases.

Leaving feedback on injections and reviews on Kombilipen Tubs, people note its affordable price.

Due to the presence of lidocaine in the composition of the injections are less painful than the introduction of analogues containing the B vitamins.

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The doctors' comments on the tablets and the solution of this drug testify that it has a pronounced positive effect in the treatment of osteochondrosis. As adverse reactions in the reviews mentioned the appearance of a slight itch of the skin and urticaria.

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They often spar: "What is better than Milgamma or Kombilipen?" Doctors answer in the following way.

Preparations Milgamma and Kombilipen are analogues, they are made by different manufacturers.

Effects on the human body, both drugs have a similar effect. However, the cost in the pharmacies of Milgamma is higher.

"With an exacerbation of osteochondrosis.

"Earlier, instead of Kombilipen, I took a more expensive preparation Milgammma in case of exacerbation of osteochondrosis, and now I accept cheaper Kombilipen, which is an analogue of Milgamma. By the ratio of "price-quality" he is the best. "

"I do not save on my health and are treated only with a proven drug - it's MILGAMMA. And I recommend it to everyone. Kombilipen in the market only 3 years, and milgamma 25 years. Milgamma is the original drug and means studied and safe. "

A source: http://remedy.ucoz.ru/index/kombilipen_ot_chego_pomogaet_instrukcija_po_primeneniju/0-326

Kombilipen injections intramuscularly - dosage, therapy regimen, contraindications and reviews

The nervous system plays an important role in the regulation and coordination of the activity of all organs and systems of the body.

There are medications that help maintain the central nervous system in a normal state to ensure the full vital activity of a person.

What mechanism is used to prevent dysfunction of nerve cells, which departments spine has a beneficial effect Kombilipen injections for intramuscular injection, try sort out.

Komliben - instructions for use

The drug belongs to the complex multivitamin means of neurotropic action, it is used for the treatment of neurological pathologies. Intended vitamins Kombilipen for:

• increased blood circulation;
• improve metabolism;
• elimination of inflammation of nerve trunks;
• restoration of damaged nerve fibers;
• Reduction of the pain syndrome caused by damage in the peripheral nervous system;
• normalization of nerve tissue conduction;
• strengthening immunity, increasing the resistance of the body's defenses to unfavorable factors: stress, smoking, drinking alcohol.

The complex effect of injections is provided by the active elements that make up Kombilipen in ampoules: benfotiamine (fat-soluble form vitamin B1) - 100 mg, pyridoxine hydrochloride (vitamin B6) - 100 mg, cyanocobalamin (vitamin B12) - 1000 μg, lidocaine hydrochloride - 20 mg. The solution for injections contains auxiliary substances:

• sodium tripolyphosphate;
• sodium hydroxide;
• potassium hexacyanoferrate;
• benzyl alcohol;
• water for injections.

Form of issue

The drug Kombilipen in the form of tablets and solutions for injections in ampoules is produced. The composition of the tablets is slightly different from the injections. Kombilipen tabs of active ingredients does not contain lidocaine, and of the additional elements in the composition of tablets are:

• talc;
• carmellose sodium;
• sucrose;
• cellulose;
• povidone;
• calcium stearate;
• polysorbate-80.

The injections represent a liquid of a pinkish-ruby color with a sharp specific odor. Kombilipen in ampoules contains two milliliters of solution for injections. The injections are packed into cell contours for 5 or 10 pieces.

In the outer cardboard box, the scarifier is placed, if there are no incisions or break points on the ampoules. The drug is dispensed in a pharmacy under the prescription of a doctor. Store the ampoules necessary at a temperature of 8 degrees indoors without solar illumination.

Shelf life of the drug is 2 years.

Pharmacodynamics and pharmacokinetics

The effect of the drug is provided by an active mixture of B vitamins, which have a beneficial effect on the nervous system human, reducing ability in inflammatory and degenerative processes in the nervous tissues and musculoskeletal apparatus. The main active substance is thiamin (vitamin B1), vitamins B6 and B12 strengthen its action and play an important role in metabolic processes. The pharmacological effect of Kombilipen is achieved due to the following properties of active substances:

1. Vitamin B1. Previously, it was called Aneurin, because its discovery is associated with a disease of the nervous system - beriberi. This disease is characterized by fatigue, decreased mental capacity, pain along the location of nerve fibers, paralysis. The substance is able to restore the function of the nervous tissue in this disease, with cerebral stroke and cerebral infarction. Its role is to provide normal nerve cells with glucose. With insufficiency of glucose, they are deformed, which leads to impairment of the functions - impulses. Thiamine provides a reduction in the heart muscle.
2. Vitamin B6. It is necessary for proper metabolism, normal blood formation, with the help of substance, processes of excitation and inhibition occur, transfer of impulses at the points of contact of the fibers of nerves. Provides the synthesis of hormones norepinephrine and adrenaline, transportation of sphingosine - a substance that is part of the nerve shell. With the help of vitamin there is the formation of serotonin, which is responsible for the sleep, appetite and emotions of a person.
3. Vitamin B12. It enters the body with food of animal origin. Participates in the biosynthesis of acetylcholine, responsible for conducting nerve impulses. It is necessary for normal hematopoiesis, with the help of a substance erythrocytes resistant to hemolysis are formed. Responsible for the synthesis of myelin - a component of the nerve shell. It is necessary for the metabolism of folic acid. Participates in the synthesis of amino acids - a building material for the cells of the epithelial layer, regulates the production of hormones by the genital organs. Increases the regenerative capacity of tissues, slows down the aging of the body. It is able to create an anesthetic effect and increase the effect of anesthetic agents, normalize blood pressure.
4. Lidocaine. Occupies an intermediate position between the active and auxiliary elements. It does not apply to vitamins, it is an anesthetic. Thanks to the substance, the injection becomes painless. In addition, the element acts on the expansion of blood vessels and promotes the absorption of vitamins by the body.

Kombilipen injections - why appoint

The ability of a vitamin preparation to favorably affect the nervous system, restore nerve tissue and their conductivity, reduce pain in inflammatory-degenerative processes in nerve fibers and the musculoskeletal system used for treatment:

• diseases of the musculoskeletal system;
• neuritis of the facial nerve;
• neuralgia of the intercostal and trigeminal nerve;
• polyneuropathy of alcoholic, diabetic etiology;
• lumbosciatica;
• pain syndrome, which is caused by degenerative changes in the cervical, cervico-brachial and lumbar spine (osteochondrosis).

As a multivitamin preparation, injections Kublipen have a general strengthening effect.

Positive results are observed with the appointment of injections to patients in the postoperative period. Good reviews received the drug from treating patients.

After the completion of the course of treatment, patients noted improvement in skin condition, energy intake, fatigue reduction.

Contraindications

To achieve the result, Kombilipen injections contain a high concentration of bioactive substances. This amount of vitamins is sometimes able, in addition to the therapeutic effect, to harm the body. It is not recommended to prescribe the drug to patients:

• if there is a reaction to the B vitamins;
• congenital or acquired cardiovascular insufficiency;
• thrombosis, thromboembolism.

Dosing and Administration

One ampoule of injections contains a fractional (daily) dose of injection - 2 ml. How to prick Kombilipen to the patient? The drug is administered intramuscularly.

This method ensures the deposition of bioactive substances, prolongs the action of vitamins - this is how best to assimilate them.

With severe symptoms, the presence of pain in the first week is prescribed daily medication.

After improving the condition, the dosage is reduced-make 2-3 injections a week. With mild forms of the disease, injections are given after 2-3 days for 7-10 days.

The duration of the period of taking injections should not exceed 14 days. The procedure for taking Kombilipen and the duration of treatment is determined by the doctor.

After 10-14 days of injections, he can prescribe taking pills.

special instructions

It is not recommended to use the drug Kombilipen to persons engaged in processes requiring increased attention or quick reaction.

This particularly applies to hazardous industries in order to exclude the possibility of injury to the patient.

It is necessary to abandon driving at the time of taking the drug, because the action of the drug slows down the reaction of the driver.

In pregnancy

The manual contains warnings about the use of injections Kombilipen during pregnancy and lactation.

This is explained by the possibility of absorbing bioactive substances into the milk while feeding a newborn or penetrating active elements through the placenta.

High concentrations of active ingredients of Kubilipen injections can harm the young body or adversely affect the development of the fetus.

In childhood

Contra-indications of the drug Kombilipen include children and adolescence. You can not prescribe the drug to children because of the content of benzyl alcohol injections.

There are no data on studies on the effects of the active elements of this drug on the children's body, so it is not recommended to take the medicine because of the risk of harming the child.

Drug Interactions

Before the appointment of injections, the doctor asks the patient about the presence of chronic diseases and the use of drugs - the drug may interact with other substances and increase their toxicity or reduce the therapeutic Effect. It should be noted:

1. Vitamin B1 completely decomposes under the influence of oxidants (sulfites), phenobarbital, riboflavin.
2. B group vitamins and Levodopa, which is prescribed for Parkinson's disease, mutually reduce the therapeutic effect of each other.
3. Vitamin B12 is incompatible with salts of heavy metals and ascorbic acid.
4. Copper accelerates the destruction of vitamin B1.

Interaction with alcohol

Drastically reduces the absorption of thiamine (Vitamin B1) alcohol, so during the reception of injections Kombilip alcohol consumption is prohibited.

You can not simultaneously take injections of the drug and medicines that contain ethyl alcohol.

This combination reduces the effectiveness of the drug Kombilipen on the patient's body.

Side effects

The injections of Kombilipen do not contain elements capable of toxic effect on the patient's body, but bioactive substances can cause the body's response in the form of:

• allergic manifestations (itching, urticaria, difficulty breathing, anaphylactic shock, swelling of Quincke);
• tachycardia from the cardiovascular system;
• metabolic disorders (excessive sweating, acne, hyperhidrosis);

Overdose

There are cases when, when injections are introduced, first, no side effects of the drug are observed, and with increasing doses of reception, a reaction occurs.

In patients with overdosage, itching can occur, urticaria, skin rashes, excessive sweating, dizziness, nausea, vomiting, disturbance of the heart rhythm.

It is necessary to immediately wash the contents of the stomach, take activated charcoal and consult a doctor for symptomatic treatment.

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Ampoules for injections Kombilipen are produced by the association "Pharmstandard" in Ufa. In pharmacies you can buy similar in composition such preparations of the domestic pharmacological industry asVitagammaandTrigamma.

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Of foreign medicines have the same propertiesNeurorubin(producer country - Norway),Neurobion(country of origin - Germany) andMilgamma(country of origin - Austria).

Foreign preparations differ from the injections of Kombilipen with an increased price.

Price of Kombilipen

Positive feedback from the Kublilen prizes received relative to a combination of low price and therapeutic effect. The cost of the drug depends on the price policy of the pharmacy network and packaging. Prices for the drug in pharmacies in Moscow are presented in the table:

Solution for intramuscular injection	Price (rubles)
Kombilipen, 5 ampoules	123-171
Kombilipen, 10 ampoules	209-263

Reviews

A source: http://sovets.net/12939-kombilipen-ukoly.html