WALZ H: the instruction and responses of people

Vals H is a preparation of an antihypertensive type of a group of peripheral vasodilators.

The drug is prescribed as a potent combined agent in the treatment of heart disease. The composition of the drug includes components such as valsartan and hydrochlorothiazide - an active substance that enhances the effect of the drug, as well as other ingredients that serve as binding elements.

On this page you will find all information about Vals H: the full instruction on the application for this medicine, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already used Valz N. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Antihypertensive drug.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much does Wales H cost? The average price in pharmacies is at the level of400 rubles.

Form of issue and composition

The drug is available in the form of tablets labeled "H" on one side and "V" on the other:

• Pink color containing 80 mg of valsartan and 12.5 mg of hydrochlorothiazide.
• Red-brown color containing 160 mg of valsartan and 12.5 mg of hydrochlorothiazide.
• Orange color containing 160 mg of valsartan and 25 mg of hydrochlorothiazide.

Excipients: croscarmellose sodium, microcrystalline cellulose, lactose monohydrate, talc, povidone K29-32, colloidal silicon dioxide, magnesium stearate.

Composition of the film sheath of tablets Valz H:

1. In a dose of 160/25 mg - opadrai II 85G23675 orange, which includes polyvinyl alcohol, macrogol 3350, talc, titanium dioxide, lecithin, iron oxide, yellow, red and black oxide.
2. In a dose of 160 / 12.5 mg - opadraj II 85G25455 red, including polyvinyl alcohol, macrogol 3350, talc, titanium dioxide, lecithin, iron oxide red dye and dye solar yellow aluminum lacquer.
3. In a dose of 80 / 12.5 mg - opadrai II 85G34642 pink, including polyvinyl alcohol, titanium dioxide, macrogol 3350, lecithin, iron oxide red, yellow and black iron oxide.

Pharmacological effect

Valz H is a combined drug that exerts an antihypertensive effect. It consists of a thiazide diuretic (hydrochlorothiazide) and an angiotensin II receptor blocker (valsartan).

Reduction of blood pressure is achieved due to the following processes:

• a decrease in the volume of circulating blood;
• increased depressor effect on the ganglion;
• reduction of pressor influence of noradrenaline and epinephrine;
• change in the reactivity of the vascular wall.

The diuretic effect of Valza H develops in 1-2 hours, reaches a maximum after 4 hours and lasts for 10-12 hours. The effect of the drug decreases in the case of a decrease in the glomerular filtration rate, and at a value of less than 30 ml / min completely stops.

The maximum antihypertensive action of Valza H develops within the first 2-4 weeks of treatment.

Indications for use

The use of Valza H is indicated for the treatment of hypertension in patients who require combination therapy.

Contraindications

The use of Valza H, according to the instructions, is contraindicated:

1. Patients with systemic lupus erythematosus;
2. In the presence of hypersensitivity to any component of the drug;
3. With hyponatremia, hypercalcemia, hypokalemia and hyperuricemia, immune to adequate therapy;
4. With violations of liver function, due to obstruction of the biliary tract, including cholestasis and biliary cirrhosis;
5. Children and teenagers under 18;
6. Pregnant women;
7. Breastfeeding mothers;
8. Patients with chronic renal failure (with QC up to 30 ml / minute), including people on hemodialysis.

Assign Wales H, but with extreme caution:

1. In the period after kidney transplantation;
2. In the case of violations of the liver function of moderate severity (with the absence of the phenomenon of cholestasis);
3. In conditions that are accompanied by a decrease in BCC (volume of circulating blood);
4. When stenosis of two renal arteries or stenosis of the artery of a single kidney.

Caution when using Valza H should be observed in patients taking:

1. Medicines that may cause an increase in the concentration of potassium in the blood, including heparin;
2. Potassium-sparing diuretics;
3. Preparations of potassium salts;
4. Thiazide diuretics.

Application in pregnancy and lactation

You can not take Vale H during pregnancy, as well as during the breastfeeding months of the baby.

Instructions for use

The instructions for use indicate that Wals H is taken internally, regardless of the time of ingestion, with a sufficient amount of liquid.

The dosages given below are indicated in the valsartan / hydrochlorothiazide ratio.

• The recommended dose is 1 tablet. 80 / 12.5 mg once a day. If the drug is not effective at this dose, it is recommended to increase the daily dose of Vals H to 160 / 12.5 mg, for those patients who showed a further decrease in blood pressure the daily dose of Valz H is 160/25 mg, respectively.

Patients with impaired renal function with CK> 30 ml / min, as well as in patients with mild to moderate violations of liver function in the absence of phenomena of cholestasis does not require a dose adjustment of the drug Valz N.

Side effects

When treating with Valz H, a number of side effects can be noted, in particular:

1. From the nervous system: feeling tired, dizzy;
2. From the digestive system: abdominal pain, diarrhea, nausea;
3. From the side of metabolism: hyperkalemia;
4. From the respiratory system: rhinitis, cough, pharyngitis;
5. Allergic reactions: pruritus, rash, serum sickness, vasculitis, angioedema;
6. Different: chest pain, viral infections, arthralgia, decreased hematocrit;
7. From the urinary system: functional renal impairment, hypercreatininaemia.

Given the combined composition of Valza H, the potential side effects associated with each of the active substances are:

1. Valsartan: insomnia, swelling, asthenia, decreased libido;
2. Hydrochlorothiazide: violation of water-electrolyte balance; often - orthostatic hypotension, nausea, vomiting, decreased appetite, urticaria, decreased potency; rarely - headache, constipation, diarrhea, abdominal discomfort, photosensitivity, jaundice, intrahepatic cholestasis, arrhythmias, depression, paresthesia, thrombocytopenia (possibly with purpura), violation view; very rarely - Lyell's syndrome (toxic epidermal necrolysis), necrotizing vasculitis, dermatological reactions (similar to systemic lupus erythematosus), dermal exacerbation of systemic lupus erythematosus, bone marrow depression, leukopenia, pancreatitis, agranulocytosis, hemolytic anemia, pulmonary edema, pneumonitis.

Overdose

In case of an overdose, there may be a marked decrease in blood pressure.

In this case, the stomach is immediately washed, intravenously, 0.9% sodium chloride solution is administered to the patient. Hemodialysis is effective only with respect to hydrochlorothiazide.

special instructions

1. Wals H is not recommended in children and adolescents under 18 years.
2. Before the treatment with the drug, it is necessary to adjust the amount of sodium ions in the blood.
3. During treatment, the amount of potassium ions, uric acid, glucose, creatinine and lipid profile should be constantly monitored in the blood plasma.
4. During therapy with the drug, it may be necessary to adjust the dosage of the oral hypoglycemic drug or insulin.
5. Reception of potassium-sparing diuretics, potassium salts, potassium salts or preparations that can increase the amount of potassium in the blood (heparin), it is necessary to observe precautions and often determine the concentration of potassium in the blood.

During the reception of Valza H, it is necessary to perform with special care work that requires a high concentration of attention and reaction speed, since some side effects of the drug (dizziness, fatigue) can affect the patient's psychomotor reactions.

Drug Interactions

1. Wals H lowers the excretion of quinidine.
2. Simultaneous reception of Vals H and methyldopa can provoke hemolysis.
3. With simultaneous therapy, the level of neurotoxicity of salicylates increases, side effects of cardiac glycosides, neurotoxic and cardiotoxic effects of lithium preparations are increased. Also, the effectiveness of curare-like muscle relaxants increases.
4. The frequency of allergic manifestations to allopurinol increases.
5. With simultaneous treatment, the effectiveness of hypoglycemic oral drugs, antidotal drugs, epinephrine, norepinephrine is reduced.
6. Preparations that bind intensely in the body to blood proteins (clofibrate, indirect anticoagulants, NSAIDs) increase the diuretic effect.
7. Vals H reduces the level of excretion of cytotoxic drugs through the kidneys and increases their myelosuppressive effects.
8. Strengthening of the hypotensive effect is noted while taking barbiturates, vasodilators, phenothiazines, beta-adrenoblockers, ethanol, tricyclic antidepressants.

Reviews

We picked up some of the people's feedback on the Valz N drug:

1. Valera. Waltz 160 \ 12.5 in the pharmacy did not find. Have advised in a drugstore to take Vasar and 160 \ 12.5 have told or said, what is it one and too. Took one cannau try. Prior to this, Lozap Plus 50 took one tablet and then two more than a month kept it in the daytime, in the evening it was normal, but in the morning the pressure reached 200 \ 65-75 \ 75-80. Advised in the evening to drink another lercamen0.2 or physiotox 0.2. drank twice Lercamen 0.2 did not help, in the morning again high blood pressure. I do not understand why drugs do not help. After all, for a month and a half of getting used to Lozap can not be. I will combine Vasar in the morning one tablet, in the evening Lercamen and Maxogamma 0.2 we will watch.
2. Natalie. WALZ 160 \ 25 take 3 years already appeared convulsions it appears necessary to take magnesium-potassium began to take cramps have passed. Авообще this preparation good before what what only preparations did not accept all in empty pressure did not hold. On povorat good.du reviews all people are different and each drug works differently need to try, it's better than to suffer from pressure.
3. Irina. I am quite happy with this drug. It is quite effective. There were no side effects at all. I took everything strictly according to the instructions. A few hours later I felt a noticeable relief, and then my condition improved.

According to reviews, Valz N is good at lowering blood pressure, but regular medication is required to maintain the effect. It is also important to choose the right dosage, in order to reduce the likelihood of side effects along with the desired therapeutic effect.

Analogues

If necessary, the drug can be replaced with an analog. Such medicines are:

• Artinova;
• Valsafors;
• Valsasin;
• "Valsakor";
• "Co-Diovan";
• "Vadsakor";
• Vanatex Kombi;
• "Duopress";
• "Valaar";
• "Valsartan granulate";
• "Nortivan";
• "Tareg";
• "Tantordio."

Before using analogues, consult your doctor.

Storage conditions and shelf life

Shelf life of the drug is three years. Blister with tablets should be kept in a dry place, which is well ventilated and reliably protected from penetration of direct light.

The medicine must be inaccessible to young children.

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