Ambrohexal (tablets, capsules, solution): instructions for use

width = Ambroghexal is a medicinal product with mucolytic, secretory and expectorant action, and active drug is ambroxol.

The mechanism of action of this drug is associated with a decrease in the viscosity of phlegm resulting from the depolymerization of mucopolysaccharides of sputum, which consists in rupturing disulfide bonds in molecules, enhancing the release of active hydrolyzing enzymes from cells Clark.

On this page you will find all information about Ambrogexal: the full instruction on the application for this medicine medium, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already applied Ambroghexal. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

A drug that has secretory, mucolytic and expectorant action.

Conditions of leave from pharmacies

The recipe is not needed.

Price list

How much is Ambrohexal? The average price in pharmacies depends on the form of release:

The cost of Ambrohexal tablets is about 84 rubles for 20 pieces.

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Capsules of prolonged action will cost 120 rubles for 10 pieces.
A bottle with a liquid for inhalation costs about 92 rubles for 50 ml.
A syrup costs about 103 rubles per 100 ml.

Form of issue and composition

To date, the drug is sold in the following dosage forms:

Tablets of 10 pieces in a blister, in one box 2, 5 or 10 blister packs;
Capsules - 10 pieces in a blister, in cardboard packs of 1, 2 or 5 blister packs;
Solution for inhalation and ingestion - 50 or 100 ml in bottles with a measuring cup in the kit;
Syrup - in bottles of 100 or 250 ml with a measuring spoon in the kit.

Active active substance of the drug is ambroxol. Auxiliary components are different and depend on the form of release.

Pharmacological effect

The mechanism of action is based on the increased stimulation of the ciliary epithelium of the bronchi. Ambrohexal improves the motor skills of the bronchi and stimulates the separation of sputum. The drug copes with a variety of therapeutic tasks: reducing cough, improving bronchial secretion, normalizing the separation of sputum, the promotion of sputum along the bronchopulmonary ways.

Indications for use

Tablets from the cough "Ambroghexal" doctor appoints in the case of a disease of the lungs or respiratory tract, accompanied by a thick sputum, the withdrawal of which is problematic (often the patient also suffers from dry cough).

The list of such ailments is as follows:

tracheitis - inflammation in the mucosa of the trachea, resulting from infection and other causes;
bronchial asthma - this pathology is of an allergic origin, with bronchial narrowing, and in the lumen a thick sputum accumulates;
cystic fibrosis - this disease has a hereditary character, differs in its severity (characterized by the production of viscous sputum);
pneumonia (pneumonia) occurs due to the presence of different bacteria;
infectious bronchitis (chronic or acute course) - it inflames the bronchial mucosa, which is provoked by bacteria or viruses;
bronchoectatic disease, which is a pathological chronic process, characterized by partial expansion of the bronchi and bronchioles (places of accumulation of viscous sputum);
obstructive chronic bronchitis - is most often provoked by a long irritation of the bronchial mucosa by smoking and the influence of various chemical compounds.

First of all, after taking the medicine, the protective function of the respiratory tract is improved.

Contraindications

Do not use Ambrohexal in treatment with hypersensitivity to the active ingredients of the drug, as well as in the ulcer of the stomach or duodenum. With severe liver and kidney damage, mucolytic is used with great caution. When there is a violation of the cough reflex, stagnation can occur due to congestion of sputum.

Application in pregnancy and lactation

The intake of Ambrohexal in pregnancy is contraindicated, because there is always the risk of adverse effects on the developing fetus.

However, due to the fact that ambroxol is a stimulator of lung development in the perinatal period, by increasing the synthesis of surfactant and blocking its disintegration, it is prescribed to pregnant women with suspected fetal hypotrophy to stimulate the maturation of the lungs, as well as the threat of premature childbirth.

Instructions for use Ambrohexal

The instructions for use indicate that the drug in the form of tablets and capsules are taken orally, washed down with water after eating.

Pillsadults and children over 12 years of age are prescribed in a dosage of 30 mg (1 tablet) three times a day for the first 2-3 days. The dosage is then reduced to 1 tablet twice a day. Children aged 6 to 12 years are prescribed half the tablet (15 mg) two to three times a day. Do not take the drug for more than 4-5 days without prescribing a doctor. During the whole treatment, the patient is recommended to drink more liquid to enhance the mucolytic effect.
A drugin the form of capsulesprescribed for adults and children over 12 years in a dosage of 1 capsule (75 mg) per day after meals in the morning or evening. Capsules are also not recommended to take more than 5 days without prescribing a doctor.
Solution for ingestion and inhalationadults and children over 12 years are prescribed 4 ml (30 mg) 3 times a day for the first 2-3 days, then - 4 ml per day. Children from 5 to 12 years are prescribed 2 ml two or three times a day. Children from 2 to 5 years - 1 ml three times a day. Children under two years - 1 ml 2 times a day only under the supervision of a doctor. The solution should be dissolved in tea, water, juice or milk.

Inhalation with Ambrohexal solution for adults and children over 5 years is performed 1-2 times a day in a dosage of 2-3 ml, children under 5 years - 2 ml each. Inhalation should be carried out using a special device.

The course of treatment can be prescribed only by the attending physician.

Side effects

Ambroxol in the AmbroGEXAL tablets is well tolerated. Sometimes it is possible to develop its side effects, which are characterized by such manifestations:

Symptoms of disruption of the digestive system - nausea, vomiting, periodic bloating, which are accompanied by dry mucous membranes. Somewhat less often there may be a pain in the abdomen, which has a spastic character.
From the nervous system - a slight violation of taste.
Change in the general well-being of a person after taking the drug, which is accompanied by a headache, fever, general weakness.
Allergic reactions to any of the components of the drug, including ambroxol - are manifested as a rash on the skin, which can be accompanied by itching. With a more pronounced body reaction, urticaria develops (a rash on the skin appears against a background of a small edema that externally like nettle burn), Quincke's edema (angioedema, swelling of the skin and subcutaneous tissue in the face or external genital area bodies). Very rarely is the development of anaphylactic shock - a severe allergic reaction, in which there is a progressive decrease in systemic arterial pressure and loss of consciousness.

The cases of development of severe skin lesions (Stephen-Jones syndrome), the occurrence of which was associated with taking medications on the basis of ambroxol, are described. Nevertheless, such skin lesions are associated more with the underlying disease, and not with the use of ambroxol. In case of any manifestations, symptoms or reaction to taking AmbroGEXAL tablets, you should stop taking them to see a doctor.

Drug Interactions

Simultaneous use with antibiotics (erythromycin, amoxicillin) leads to an increase in their concentration in sputum and bronchopulmonary secretions.

When combined with antitussive drugs containing codeine, sputum congestion is possible due to the depression of the cough center.

Ambrohexal can be used with drugs used in the bronchial syndrome (bronchospasmolytics, glucocorticosteroids, cardiac glycosides, diuretics).

Reviews

According to feedback, Ambroghexal in the form of tablets is very well tolerated and demonstrates high effectiveness in the treatment of severe dry cough. At treatment by a preparation practically there are no adverse reactions. Many patients like it because of its low cost and its availability. The syrup has the same pharmacological properties and attracts patients with a pleasant sweetish flavor. Usually, a week after the start of therapy, cough in most patients disappears without a trace.

Inhalation with Ambrohexal solution also has positive feedback. The main advantages of the drug are the variety and convenience of the release forms, acceptable results of treatment and quick recovery against the background of its use. Parents note that inhalations with Ambroghexal and saline help in the shortest possible time to save children from excruciating coughing attacks. However, there are references to the unpleasant taste of this dosage form.

Analogues

There are many medications with an effect similar to Ambrohexal. The price of analogues can be either higher than the original, or slightly lower, but there is no significant difference. The use of one of the substitute drugs requires the approval of the attending physician, since it is necessary to prescribe a specific drug with the rationale for the specificity of the development of the disease. The most famous and affordable analogs of Ambrohexal in pharmacies with the price (in rubles) for 20 tablets, 30 ml of active substance: