Cycloferon is a domestic antiviral immunomodulating drug, the active ingredient in which is meglumine acridon acetate.
Being an inducer of endogenous interferon, the drug has a wide range of pharmacological activity. On the Russian pharmaceutical market, he has been present for about 20 years, having proved himself to be an effective, but an uneasy tool that requires certain knowledge and practical experience from the doctor.
Cycloferon is a promising biofunctional drug with a wide range of pharmacological effects, allowing to use it both in treatment and in the prevention of viral diseases. In view of its good tolerability, it has been successfully used in pediatrics, as well as in elderly patients.
Clinical and pharmacological group
Antiviral and immunomodulating drug. Interferon synthesis inductor.
Terms of sale from pharmacies
Can buywithout a doctor's prescription.
Price
How much does Cycloferon cost in pharmacies? The average price is at the level of220 rubles.
Composition and form of release
The product is available in tablets, there is also a solution, the liniment Cycloferon. Drops, candles and other forms of drugs are not produced. What type of release should be used for treatment is determined by the doctor.
- Solution Cycloferon contains as active ingredient acridonacetic acid, also in the solution includes auxiliary substances: stabilizing and salt-forming additive, water for injections.
- Tablets Cycloferon have a composition of acridone acetic acid as an active ingredient. Also in their composition are inactive components: calcium stearate, methylcellulose.
- The liniment of Cycloferon has, as an active ingredient, acridonacetic acid in the form of N-methylglucamine salt, as well as auxiliary ingredients , -propylene glycol up to 100%, 0.1% catapol.
Pharmacological effect
Cycloferon has 2 pronounced effects: antiviral and immunomodulating, as well as anti-inflammatory, antiproliferative (overwhelmingly excessive cell growth) and antitumor effect. In the body meglumine acridonacetate potentiates the synthesis and accumulation in the organs and tissues of significant titers of interferons α and β. The greatest content of interferons is noted in structures rich in lymphoid tissue: spleen, lungs, intestinal mucosa, liver.
Cycloferon activates bone marrow stem cells, provides the formation of granulocytes. Normalizes the ratio of antigen-suppressing T suppressors and T-helpers that enhance the adaptive immune response. Activates killer cells and T-lymphocytes. This effect is especially important in immunodeficiencies of a different nature, since it leads to a correction of the immune status. Penetrates into the brain tissue.
Thus, cycloferon:
- leads to marked improvement in common viral diseases like influenza, herpes, enterovirus infection, and less common pathologies: tick-borne encephalitis, hepatitis, cytomegalovirus and papillomatous infections;
- normalizes the immune status in HIV-infected people;
- has antimicrobial and anti-chlamydial action;
- prevents the onset of tumor processes due to antimetastatic and anticarcinogenic effects;
- suppresses autoimmune reactions, thereby reducing the severity of pain and inflammatory phenomena in rheumatic diseases and systemic pathologies of connective tissue;
- causes an improvement in the balance of immunity, with topical application characterized by antiproliferative action and rapid elimination of inflammation.
Indications for use
What helps tsikloferon? Tablets are prescribed as part of complex therapy in adults in such cases:
- influenza and acute respiratory infections;
- herpetic infection.
As part of complex therapy in children aged 4 years and older:
- influenza and acute respiratory infections;
- herpetic infection.
Prevention of influenza and acute respiratory infections in children aged 4 years and older.
In this case, the injections have a wider range of applications. They are used in such diseases as part of complex therapy:
- HIV infection (stages 2A-2B);
- Neuroinfections: serous meningitis and encephalitis, tick borelliosis (Lyme disease);
- viral hepatitis A, B, C, D;
- herpetic infection;
- cytomegalovirus infection;
- secondary immunodeficiencies associated with acute and chronic bacterial and fungal infections;
- chlamydial infections;
- rheumatic and systemic connective tissue diseases (rheumatoid arthritis, systemic lupus erythematosus);
- degenerative-dystrophic diseases of joints (including deforming osteoarthritis).
As part of complex therapy in children:
- viral hepatitis A, B, C, D;
- herpetic infection;
- HIV infection (stages 2A-2B).
Contraindications
Abstract for the preparation contains the following contraindications for its use:
- cirrhosis of the liver (decompensation stage);
- high sensitivity to the components of the agent;
- pregnancy, breast-feeding;
- the child's age is up to 4 years (due to imperfect swallowing act).
Also, certain contraindications exist in the presence of patients with diseases of the digestive system during the phase of exacerbation. Cycloferon should be used cautiously in the presence of allergic reactions in the anamnesis.
Intended use for pregnancy and lactation
The drug Cycloferon is not prescribed to pregnant women, as experience with the use of tablets in obstetric practice is lacking, and safety for the mother and fetus is not established.
If it is necessary to prescribe Cycloferon tablets to breastfeeding mothers, women should decide whether to complete lactation, since it is not known about the ability of the main active substance to excrete with breast milk.
Dosage and route of administration
As indicated in the instructions for use Cycloferon is taken orally 1 time / day 30 minutes before meals, without chewing, drinking 1/2 cup of water. The dose of the drug depends on the age of the patient.
- Adults and children over 12 years of age are prescribed 450-600 mg (3-4 tablets) per reception.
- Children aged 7-11 years are prescribed 300-450 mg (2-3 tablets) per reception.
- Children aged 4-6 years are prescribed 150 mg (1 tab.) At the reception.
It is advisable to repeat the second course 2-3 weeks after the end of the first course.
Adults
In the treatment of influenza and acute respiratory infections, the drug should be taken at 1, 2, 4, 6, 8th day (treatment course - 20 tablets). Treatment should begin with the first symptoms of the disease. In severe influenza in the first day should take 6 tablets. preparation. If necessary, additional symptomatic therapy (antipyretic, analgesic, expectorants) is performed.
For herpetic infection, the drug should be taken on 1, 2, 4, 6, 8, 11, 14, 17, 20, 23-day (treatment - 40 tab.) Treatment is most effective when the first symptoms of the disease appear.
Children aged 4 years and over
In the treatment of influenza and acute respiratory diseases, the drug should be taken at a dose appropriate to age on 1, 2, 4, 6, 8, 11, 14, 17, 20, 23-day. The course of treatment is from 5 to 10 receptions, depending on the severity of the condition and the severity of clinical symptoms.
In the treatment of herpetic infection, the drug should be taken at 1, 2, 4, 6, 8, 11, and 14 days. The course of treatment varies depending on the severity of the condition and the severity of clinical symptoms.
For emergency nonspecific prophylaxis of influenza and acute respiratory diseases (in direct contact with patients influenza and acute respiratory infections of other etiologies, during the flu epidemic) the drug should be taken on the 1st, 2nd, 4th, 6th, 8th day. Next, you should take a break for 72 hours (3 days) and continue the course on 11, 14, 17, 20, 23 days. The general course is from 5 to 10 receptions.
Cycloferon: instructions for use
Adults Cycloferon is given in / m or / in 1 time / day according to the basic scheme: every other day. The duration of treatment depends on the disease.
- In HIV infection (stage 2A-2B), the drug is prescribed, according to the basic scheme, 10 injections of 500 mg and then on a maintenance schedule once every three days for 2.5 months. The course is repeated after 10 days.
- In immunodeficient conditions, the course of treatment consists of 10 injections of IM in the basic scheme in a single dose of 250 mg. The total dose of 2.5 g. The repeated course is conducted in 6-12 months.
- In rheumatic and systemic connective tissue diseases, 4 courses of 5 injections are prescribed according to the basic scheme, 250 mg with a break of 10-14 days. The doctor determines the need for a repeat course individually.
- With herpetic and cytomegalovirus infections, the drug is prescribed according to the basic scheme - 10 injections of 250 mg. The total dose of 2.5 g. Treatment is most effective at the beginning of an exacerbation of the disease.
- With neuroinfections, the drug is administered according to the basic scheme. The course of treatment - 12 injections of 250-500 mg in combination with etiotropic therapy. The total dose of 3-6 g. Repeated courses are conducted as needed.
- With chlamydial infection treatment is carried out according to the basic scheme. The course of treatment 10 injections of 250 mg. The total dose of 2.5 g. The second course is 10-14 days later. It is advisable to combine Cycloferon with antibiotics.
- In acute viral hepatitis A, B, C, D and mixed forms, the drug is administered by the basic scheme of 10 injections of 500 mg. The total dose is 5 g. With prolonged course, repeated courses are carried out 10-14 days later.
- In chronic viral hepatitis B, C, D and mixed forms, the drug is administered by the basic scheme of 10 injections of 500 mg, then according to the supporting scheme 3 times per week. within 3 months in the complex therapy. It is recommended in combination with interferons and chemotherapy. Repeat the course in 10-14 days.
- In degenerative-dystrophic diseases of joints, 2 courses of 5 injections of 250 mg are prescribed with a break of 10-14 days according to the basic scheme. The doctor determines the need for a repeat course individually.
ChildrenTsikloferon appoint or nominate in / m or in / in 1 times / sut. The daily therapeutic dose is 6-10 mg / kg body weight.
- In acute viral hepatitis A, B, C, D and mixed forms, 15 injections of the drug are carried out according to the basic scheme. With a prolonged course of infection, the course is repeated after 10-14 days.
- In chronic viral hepatitis B, C, D, the drug is administered according to the basic schedule of 10 injections and then on a maintenance schedule 3 times a week for 3 months as part of complex therapy. Recommended use in combination with interferons and chemotherapy.
- In HIV infection (stages 2A-2B), a course of 10 injections is prescribed according to the basic scheme and then on a supportive schedule once every 3 days for 3 months. Repeat the course after 10 days.
- With herpetic infection, a course of 10 injections is carried out according to the basic scheme. If the replicative activity of the virus is maintained, the course of treatment is continued according to a supportive scheme with the administration of the drug once every 3 days for 4 weeks.
Adverse Reactions
According to reviews, Cycloferon is well tolerated by patients. Sometimes undesirable consequences in the form of allergic reactions are possible.
Overdose Symptoms
Cases of drug overdose are very rare, but in some cases, when the dose is exceeded, symptoms of adverse reactions of the body may appear.
special instructions
Before you start using the drug, read the special instructions:
- If there is no curative effect, the patient should consult a doctor.
- In the treatment of influenza and SARS, in addition to Cycloferon therapy, symptomatic therapy should be given.
- In cases of thyroid gland diseases, the use of Cycloferon should be carried out under the control of the endocrinologist.
- Before taking the drug, you need to consult a doctor with patients with digestive system diseases in the phase of exacerbation (erosion, gastric ulcers and / or duodenal ulcers, gastritis, duodenitis) and allergic reactions in the anamnesis.
- If the next dose of the drug is missed, then at the first opportunity, without taking into account the time interval and doubling the dose, continue the course of treatment according to the scheme started.
Compatibility with other drugs
The drug and analogues of Cycloferon are compatible with all drugs used to treat the above diseases, including chemotherapy drugs and interferons.
Patient Reviews
We offer you to read reviews of people who used Cycloferon:
- Irina. With the flu I take tsikloferon in tablets - it helps. Headache has ceased to hurt and joints almost do not break. I also drink Erespal from a cough. The doctor prescribed Kagocel. Has told or said, that Tsikloferon it is possible to not accept any more (accepted 1, 2 and 4 days). The effect of Kagocel has not yet felt, and Cycloferon significantly helped at the beginning of the disease.
- Pauline. Cycloferon is good for me, I'm happy. I always take it for cold and flu, and my husband too. It helps to easily transfer the disease, quickly recover. I also noticed that if I had time to take it at the first symptoms of the disease, I did not get sick. The husband still takes with him in the business trips, takes it right away if any of the colleagues gets sick - the virus does not take it, it remains healthy. And by the way, what means there is no normal research? I've been wandering the Internet, I do not remember what I was looking for, but I went to the copper py. Just in the section of Cycloferon. That's fair, such a number of scientific articles on the drug you will not find much. I was under the impression. Still there is a conclusion from the Research Institute of Flu, laconically and in an accessible language everything is painted, called "Conclusion on the effectiveness of cycloferon."
- Sasha. I had and is conjunctivitis. To the oculist issue coupons only for a month in advance, but I needed a hospital, so I turned to the therapist. Together with conjunctivitis flows from the nose. Those. it was incomprehensible, conjunctivitis as an adenovirus infection, or the eyes so affect the nose and throat. One of the therapists advised me to take tests for cytomegalovirus, herpes simplex and something else. Also has appointed or nominated tsikloferon to pierce. I communicate with a friend who has a doctor. She said she's a very good drug. Very effective, which helps with orvi. According to the scheme I bought myself 10 ampoules. Approximately after 5 at me flowed from a nose and eyes as on orvi (before I still accepted a Flemoxinum). My eyes were breaking, the temperature rose to 37.2, although it was not there at all. Now there are 2 ampoules left, yesterday the temperature was again. Today, too, even though I did not go out of the house. Such a feeling, as if the immunity is further weakened.
Analogues
You can replace Cycloferon with the following medicines:
- Amizon refers to the substitutes for Cycloferon for a pharmaco-therapeutic group. On sale, it is in the form of tablets, which are prescribed for the purpose of treating acute viral respiratory diseases in adults. Pregnancy and lactation are a contraindication to the appointment of Amizon.
- Kagotsel - domestic antiviral drug, produced in tablets. He is a substitute for Cycloferon in the clinical and pharmacological group. It can be given to patients older than 3 years for treatment and prevention of ARVI, including influenza. Adults can take pills for herpes infections.
- Amiksin as an active ingredient contains trilon. Tablets of 60 mg can be prescribed for children older than 7 years with the aim of treating ARVI. The drug in a dosage of 125 mg is prescribed for adults to treat and prevent ARVI. Also, it is prescribed for adults with herpes, cytomegalovirus infection, hepatitis, viral etiology, chlamydia, tuberculosis.
- Arbidol belongs to antiviral drugs and is a substitute for the drug Cycloferon by the pharmacological group. It is produced in capsules, tablets, powder, from which a suspension is made for oral administration. In a suitable dosage form, the drug is allowed for patients older than 2 years. Arbidol is contraindicated until 14 weeks of pregnancy.
Before buying an analogue, consult your doctor.
Shelf life and storage conditions
Cycloferon in tablet form is stored in a dry, dark place at room temperature for no longer than 24 months.
The solution for injection is stored at room temperature for no longer than three years. It is allowed to freeze the drug. In the formation of sediment or discoloration, the preparation is not suitable for use.
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