Spray, solution and candles Imunofan: instructions for use

Imunofan is a preparation with detoxification, immunoregulating, antioxidant, hepatoprotective effect and restoring balance of oxidation-antioxidant reactions of the body.

On this page you will find all information about Imunofan: the full instruction on the application for this medicine, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already used Imunofan. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Immunostimulating drug with hepatoprotective, detoxification, antioxidant action.

Conditions of leave from pharmacies

Available without a prescription.

Price list

How much is Imunofan? The average price in pharmacies is at the level of500 rubles.

Form of issue and composition

The drug is available in the form of suppositories rectal, spray nasal dosed and solution for subcutaneous and intramuscular injection.

The suppository contains 100 μg of imunofan, additional ingredients - water, solid fat, glycine, tween 80.

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The spray contains imunofan, additional substances benzalkonium chloride, sodium chloride, sodium edetate, glycine, water.
Imunofan in ampoules contains 50 μg of imunofan in each ampoule. Also in the composition of the drug there are additional substances - sodium chloride, glycine, water for injections.

Pharmacological effect

It has a pronounced immunostimulating, antioxidant, detoxifying and hepatoprotective (hepatic cell protective) properties. Imunofan is able to suppress the development of cell resistance to antitumor drugs.

The drug begins to act after 2-3 hours from the time of admission, and the full effect of the use of Imunofan develops after several months. Conditionally, the action of the drug in question can be divided into three main phases.

The rapid phase begins a couple of hours after taking the drug and lasts for three days. During this period, the drug exhibits its detoxification function. If a patient has liver damage of a toxic or infectious origin, then the use Imunofana helps reduce bilirubin and liver enzymes, reduce the phenomenon of cytolysis.
The middle phase enters its development on the third day from the moment of taking the drug and lasts up to ten days. During this period, the death of intracellular organisms occurs, marked against the background of activation of phagocytosis. In this regard, patients may exacerbate chronic foci of inflammation.
The slow phase begins on the tenth day from the time of taking the drug and can last up to four months. During this period, the drug manifests its immunomodulatory effect. There is a regulation of humoral and cellular immunity, the formation of IgA, there is an increase in the number of specific antibodies.

Imunofan is well combined with anti-inflammatory agents (both with steroids, and with non-steroidal anti-inflammatory drugs).

Indications for use

According to the instructions, Imunofan is indicated for the prevention and treatment of chronic inflammatory diseases of various etiology, immunodeficiency and toxic states.

In addition, the drug is prescribed:

Spray nasal - with the therapy of acute forms of infectious and inflammatory pathologies.
Solution for injections and suppositories rectal - for vaccination against viral and bacterial infections as an adjuvant (adults only).

Contraindications

The drug is contraindicated:

Women during pregnancy, complicated by Rh-conflict between mother and fetus.
With individual intolerance of the drug.
In childhood, up to two years.

In addition, the solution for injections and suppositories rectal is contraindicated to be used in cases of Rhesus-complicated pregnancy.

Caution is advised to use nasal spray during pregnancy and breastfeeding.

Application in pregnancy and lactation

During pregnancy and during feeding, Imunofan is used with caution, since clinical data on its effect to date is not enough. It can not be used in pregnancy, which occurs with a Rh-factor conflict.

Instructions for use

The instructions for use indicate that Imunofan is administered subcutaneously or intramuscularly 1 ml once a day.

For the treatment of cancer patients, the drug is prescribed to 1 ml once a day, every other day, before chemotherapy or radiation therapy, a course of 3-5 injections is required, before the operative treatment a course of 2-3 injections is needed. With oncological diseases III-IV stage, the following scheme is recommended: 1 ml once a day, every other day, a course of treatment of 5-7 injections, then another 2-3 such courses, with a break of 20 days.
For the treatment of opportunistic infections 1 ml once a day, with an interval of three days. The course of treatment is 10-15 ml.
For the treatment of brucellosis and chronic viral hepatitis, 1 ml once a day, with an interval of 4 days. The course of treatment is 8-10 ml.
For the treatment of diphtheria, 1 ml once a day, every day. The course of treatment is 8-10 ml. For the treatment of bacterial carriers 1 ml once a day, with
an interval of 4 days. The course of treatment is 3-5ml.
To treat patients with a tank. endocarditis, burns and long-term non-healing wounds, 1ml once a day. The course of treatment is 7-20 ml.
For the treatment of rheumatoid arthritis, 1 ml once a day, with an interval of 4 days. The course of treatment is 8-10 ml (up to 20 ml).
For the treatment of patients with psoriasis, the drug is prescribed 1 ml once a day, every other day. The course of 8-10 injections.
As adjuvant 1 ml once, on the day of vaccine prevention.

Instructions for candles

Use rectally. Single and daily dose - 100 mcg (1 suppository).

In the treatment of cancer patients in the scheme of radical combined treatment (chemo-radiotherapy and surgery): once, daily, course of treatment of 8-10 suppositories before chemo-radiation therapy and operation with the subsequent continuation of the course during the entire treatment period.
In patients with a common tumor process (III-IV stage) of different localization in the form of complex or symptomatic therapy: once, daily, the course of treatment 8-10 suppositories, with a break of 15-20 days and the repetition of courses during the entire period of subsequent treatment.
In children with malignant disease of the hematopoietic or lymphoid tissue: 1 time / day, daily, treatment course 10-20 suppositories. The drug should be administered throughout the course of chemotherapy and after completion of the course to prevent the development of toxicosis.
In the complex therapy of children with papillomatosis of the larynx and oropharynx: 1 time / day, daily, treatment course 10 suppositories.
For opportunistic infections (cytomegalovirus and herpetic infection, toxoplasmosis, chlamydia, pneumocystis, cryptosporidiosis): 1 time / day, daily, treatment course 10 suppositories.
In the complex therapy of HIV infection: 1 time / day, daily, treatment course 15-20 suppositories. If necessary, repeat courses should be conducted in 2-4 weeks.
With chronic viral hepatitis and chronic brucellosis: 1 time / day, daily, the course of treatment of 15-20 suppositories, to repeat the recurrence should be repeated courses in 2-3 months.
With diphtheria: 1 time / day, treatment course 8-10 suppositories. With diphtheria bacteriocarrier - 1 time in 3 days - 3-5 suppositories.
In the treatment of burns of III-IV degree with the phenomena of toxemia, septicotoxemia, in surgical patients with septic endocarditis, long-term non-healing wounds of the extremities, purulent-septic complications: 1 time / day, daily, the course of treatment 7-10 suppositories, if necessary, the course of the drug should continue to 20 suppositories.
With bronchial-obstructive syndrome, cholecystopancreatitis, rheumatoid arthritis: 1 time in 3 days, treatment course 8-10 suppositories, if necessary, the course should continue to 20 suppositories at the same interval.
In the treatment of psoriasis: 1 time / day, daily, treatment course 15-20 suppositories.
In adults, in the vaccination scheme - once a day on vaccination.

Instruction for spray

Intranasally. When using the bottle, hold it upright with a spray gun. Remove the protective cap from the sprayer. Before the first use, fill the dosing pump by pressing on the wide rim of the sprayer 3-4 times. Insert the nebulizer into the nasal passage with the vertical position of the head. Press the wide rim of the spray gun a single time until it stops. In one dose of the drug contains 50 mcg imunofana. The daily dose should not exceed 200 mcg.

In the complex therapy of acute and chronic infection-related diseases, accompanied by symptoms of intoxication and immunodeficiency condition, Imunofan appoint 1 dose (50 mcg) in each nasal passage 2 times / day, daily for 10-15 days.

For opportunistic infections (cytomegalovirus and herpetic infection, toxoplasmosis, chlamydia, pneumocystis, cryptosporidiosis):

1 dose (50 mcg) in each nasal passage 2 times / day, daily, treatment course 10-15 days. If necessary, it is possible to repeat the course in 2-4 weeks.

In chronic viral hepatitis and chronic brucellosis:

1 dose (50 mcg) in each nasal passage 1 time / day, daily, treatment course 10-15 days, to repeat the course should be repeated courses in 4-6 months.

In the scheme of treatment of patients with HIV infection:

1 dose (50 mcg) in each nasal passage 1 time / day, daily, for 10-15 days. If necessary, it is possible to repeat the course in 2-4 weeks.

In the treatment of cancer patients in the scheme of radical combined treatment (chemoradiotherapy and surgery):

1 dose (50 mcg) in each nasal passage 1 time / day, daily, for 8-10 days before chemotherapy and surgery followed by continuation of the course throughout the treatment period.

In patients with a common tumor process (III-IV stage), different localization in terms of complex or symptomatic therapy:

1 dose (50 mcg) in each nasal passage 1 time / day, daily, for 8-10 days. If necessary and the presence of severe toxicosis is recommended to re-conduct the course.

Side effects

Reception of the drug is not accompanied by any side symptoms. Only in rare cases, patients experienced side effects in the form of allergic reactions.

Overdose

In reviews of Imunofan there are no reports of an overdose with a drug.

special instructions

For all dosage forms of Imunofan, a combination with anti-inflammatory (steroidal and non-steroidal) agents is allowed.

With the use of a spray, the effectiveness of other types of drug therapy is enhanced. Using the active substance of the drug helps to overcome resistance to glucocorticosteroid therapy.

Due to the activation of phagocytosis, the exacerbation (short-lived) of the centers of chronic inflammation, which are maintained due to the persistence of bacterial and viral antigens, is likely.

Drug Interactions

When treating Imunofan, no negative reaction was observed when interacting with other drugs.

Reviews

We picked up some of the people's comments about the Imunofan drug:

Julia. Has pierced in the beginning of September of 10 ampoules of an intunofan, to the husband has bought or purchased in the form of drops in a nose, tk he is afraid of nyxes. And what do you think, fell down at the end of September with a terrible purulent sore throat, then everything went to the bronchi. I got sick both my husband and my mother-in-law. Now so much money was thrown out for treatment, with all the sprays, gargles, anti-expectorants, antibiotics, tablets for resorption, it's just creepy how much we managed all the treatments. All the hope was on imunofan which let us down, and he too is not cheap worth the injection of 5 pcs - 467 rubles, pierced 10 pcs and nasal spray 785 rubles. They just threw money away. I do not advise anyone, do not waste your money.
Olga. Imunofan is an excellent, and most importantly, very effective drug. I have chronic hepatitis C. And so, after a course of treatment imunofanom to me it becomes much better. Many side effects of hepatitis go missing. The course is 20 days with a repetition every 6 months. Well, I constantly take hepatoprotectors. Has noticed still, as to hurt or be ill; be sick an ORVI became much less often. For a year almost did not hurt. Once there was a cold, and the flu in early 2016 generally passed me by. Although every day I use public transport. It happens several times a day, not just for work and back. This is my salvation.

Analogues

There are no complete structural analogs for the active substance of the drug Imunofan.

Nevertheless, among the many medicines available in pharmacies, you can buy the following drugs similar to Imunofana:

Anaferon;
Alkimer;
Arbidol;
Wobenzym;
Immunal;
Groprinosin;
IRS 19;
Pyrogenal;
Derinat;
Timogen and many others.

Before using analogues, consult your doctor.

Storage conditions and shelf life

According to the instructions, Imunofan is recommended to store in a place protected from sunlight, inaccessible to children. Storage temperature2-10 ° C.