Dolobien gel: instructions for use

Dolobien gel is an anti-inflammatory, anti-edematous, analgesic drug that is intended for external use.

Although there are many such medicines on the pharmaceutical market, it is the most popular, since it is a universal remedy for sprains, bruises and other injuries in everyday life and in sports.

On this page you will find all information about Doloben: full instructions for use on this medication, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already applied gel Dolobene. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

The drug with anti-inflammatory, antiexudative, analgesic, antithrombotic and tissue regeneration-improving action for external use.

Conditions of leave from pharmacies

Available without a prescription.

Price list

How much is Dolobene? The average price in pharmacies is at the level of400 rubles.

Form of issue and composition

Dolobene is available in the form of a gel, the color of which is clear to slightly cloudy, from colorless to slightly yellowish. The drug is packaged in tubes of 50 and 100 g.

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The gel contains 3 active ingredients:

Dexpanthenol;
Heparin sodium;
Dimethyl sulfoxide.

In 100 grams of active ingredients are contained in an amount of 2.5 g / 50 thousand IU / 16.66 g.

Pharmacological effect

The drug has anti-inflammatory, antithrombotic and aneliziruyuschim action. This medicine is available as a gel. Its properties are influenced by the constituent active ingredients:

Heparinimproves microcirculation, acts as an anti-inflammatory agent. It helps to regenerate the connective tissue.
Dexpanthenolpromotes rapid regeneration of damaged tissues. It has an emollient and anti-inflammatory effect, stimulates epithelization processes. It is one of the components of coenzyme, therefore it participates in many metabolisms. Thanks to it, the tolerance of Dolobene-gel is improved.
Dimethylsulfoxideremoves inflammatory processes, edema and has a local analgesic property. During inflammation in soft tissues, hydroxyl radicals are produced in large quantities, which are capable of destroying the tissues around. Active substance Dimethyl sulfoxide depresses their activity and stops the inflammatory process, and also removes swelling. Pain syndrome is reduced due to the fact that due to the action of the substance, conduction of pain impulses in neurons decreases. Dimethyl sulfoxide also locally improves subcutaneous metabolic reactions. The active substance promotes more effective and deep carrying out of other medicinal products if they are applied simultaneously with Dolobene gel.

Indications for use

What helps? Dolobene gel is used in the following cases:

with swelling of soft tissues;
with thrombophlebitis;
with acute neuralgia;
when stretching muscles, tendons and ligaments;
with periarthritis of the humeroscapular joints;
with inflammation of tendons (tendinitis) and tendon sheaths;
with bruises, injuries with intact skin;
with diseases of the musculoskeletal system, including with osteochondrosis, with arthrosis, arthritis;
with hematomas and joint injuries.

Contraindications

Contraindications to the use of Dolobene are:

Bronchial asthma.
Children under 5 years.
Open wounds (in particular, at the site of application of the drug).
Severe functional disorders of the liver.
The period of bearing of the child and lactation.
Severe disorders of the cardiovascular system.
Hypersensitivity to the main and auxiliary components of the drug.

Application in pregnancy and lactation

To apply gel Dolobene during pregnancy is prohibited. There are no clinical studies data on the effect of the drug on fetal development, so doctors prefer not to risk the health of the mother and baby.

If there is a need to apply the drug during the breastfeeding period of the child (lactation), the baby should be transferred to artificial food, because it is proved that the active substance dimethylsulfoxide can be excreted in breast milk.

Instructions for use

The instructions for use indicate that Dolobene gel is applied to the skin surface directly over the damaged area 2-4 times a day. Do not use freshly applied gel with a bandage. It is necessary to wait until the gel completely penetrates into the skin, and then make a tight, tight bandage. Dolobene is used in physiotherapeutic procedures (iontophoresis) under the cathode.

It is also used in phonophoresis as a contact gel. Thanks to the active substances of the drug, the therapeutic effect of ultrasound therapy is increasing.

The duration of exposure to the drug depends on the symptoms of the disease.

Side effects

The drug may contribute to the development of the following undesirable side effects:

Allergic reactions: urticaria, in rare cases - angioedema.
Local skin reactions: a feeling of itching and burning in the place of application, redness.

Other side effects: in some cases, the patient may begin to worry about the unpleasant odor of garlic from the mouth. This is due to the presence of dimexide in the formulation. There is a possibility of a violation of taste sensations. Nausea, headache, stools, difficulty breathing may occur.

Overdose

Data on the occurrence of an overdose of the drug by the manufacturer are not provided. Most likely, this is due to a small concentration of active components that are rapidly absorbed, and are not able to cause symptoms of intoxication.

special instructions

In case of skin reactions, treatment should be discontinued.
Before applying Dolobene should thoroughly clean the skin of other medicines, cosmetics or any chemical agents.
During the treatment, photosensitivity of the skin can be intensified, therefore, during its application, intensive sunbathing and visiting the solarium should be limited.
Due to the high absorption of dimethylsulfoxide, do not use Dolobene in combination with other ointments and gels.
Doloben can not be applied to the mucous membranes of the eyes, nose, mouth, open wounds or to damaged areas of the skin (due to irradiation, severe sunburn, post-operative scars).

Drug Interactions

With a joint external application, Dolobene can enhance the penetration of other drugs through the skin.

With the simultaneous use of medicines containing sulindac (NSAIDs), the development of peripheral neuropathy is possible with the drug Dolobene.

Benefits

The main advantage of the drug is its complex effect, which allows to carry out in three directions simultaneously: anesthesia and removal of puffiness, elimination of inflammation, regeneration of damaged fibers and skin cells. The effect of treatment is noted already with the first application of the gel.

Alcohol base freezes pain, by rapid evaporation of moisture from the skin, helping to strengthen the analgesic effect.

Reviews

We picked up some of the people's comments about the drug Dolobene:

Kostya. Dislocation of the ankle joint, the pain was severe, after several applications the pain was gone, the swelling was asleep, compared to other ointments, it's super!
Irina. I was convinced that Dolobene is an excellent aid for various joint pains. I had numerous knee bruises, so now I often feel aching pain. Now I use only this ointment, before going to bed I just rub my knees and sleep peacefully. I tried to buy cheaper ointments, but there was practically no effect. I think it's not worth saving for health, it's better to use a remedy that really helps.
Larissa. For the first time I started using gel after fracture of my hand. The surgeon removed the plaster and advised him to apply on the arm three times a day. I immediately saw the result. Edema decreased, and the arm at the site of the fracture ceased to hurt. Now I am taking a course of treatment for bursitis and again Dolobene came to my rescue. It is well absorbed, does not leave traces. Of course, for a pensioner it is expensive, but the effect of using it is worth it.

Analogues

The average cost of the medicine is about 300 rubles. For this reason, buyers are looking for analogues of Dolobene gel at a lower price. Direct replacement can be a preparation of Gepatrombin S, which contains the same medicinal substances, the average cost of this medicine is about 250-270 rubles. Other drugs similar in effect differ in the presence or absence of some other substances in the composition.

The following options are among the group of drugs similar to Dolobene: