Citramon

Citramone belongs to the group of non-narcotic drugs, analgesics. This is a complex medical device, the active ingredients of which are a compound of paracetamol, caffeine and acetylsalicylic acid.

Due to the complex effect, the drug has an anti-inflammatory, aneliziruyuschee, anesthetic, vasodilator effect on the centers of inflammation centers. Citramon is used to reduce the effects of various pains of low intensity - headaches, toothaches, muscle aches, periodic spasms.

Also actively used in feverish conditions during influenza. To understand what helps the drug and when it is prescribed, you need to examine its composition and action.

Clinical and pharmacological group

An analgesic-antipyretics of a combined composition.

Terms of sale from pharmacies

Can buywithout a doctor's prescription.

Price

How much does Citramone cost in pharmacies? The average price is at the level of11 rubles.

Composition and form of release

To date, the number of manufacturers of the drug is growing steadily, so the composition of Citramon will be slightly different. However, the main active substance is not subject to change.

The composition of Citramon "classical" included:

• 0.25 g of acetylsalicylic acid (Acidum acetylsalicylicum);
• 0.17 g of phenacetin (Phenacetini);
• 0.027 g caffeine (Caffeine);
• 0.021 g of citric acid (Citric acid);
• and 0.014 g of cocoa.

This composition has ceased to exist today, andadd phenacetin, since it is capable of causing serious complications and side effects. Most often, the composition of the combined preparation now includes the main three components:

• aspirin (Acidum acetylsalicylicum);
• paracetamol (Paracetamoli);
• and caffeine.

Different kinds of Citramon

Depending on the manufacturer's firm, Citramon happens with a different composition and name. To date, produce its following varieties:

• Citramon P - contains aspirin, caffeine and paracetamol. The use of Citramon P is contraindicated in persons under 14 years of age. Dosage for adults is from 1 to 2 tablets three times a day. Between receptions should be a gap (not less than 6 hours).
• Citramon Forte - contains in addition to aspirin, caffeine and paracetamol, as well as citric acid. Auxiliary components: cocoa, potato starch, magnesium stearate. The addition of citric acid to the drug is not accidental, it stabilizes cellular respiration at the biochemical level. Assign Citramon Forte to persons from 14 years and above, the dosage is 1-2 tablets up to three times a day.
• Citramon Darnitsa is the most popular among the rest. The composition includes aspirin, paracetamol, caffeine, citric acid. Auxiliary components: starch, cocoa, calcium stearate and polyvinylpyrrolidone. The rules of application do not differ from previous preparations.
• Citramon Ultra - consists of acetylsalicylic acid, paracetamol and caffeine. Produced in the form of capsules, appoint 1-2 capsules up to four times a day. The daily dose should not exceed eight capsules.

Pharmacological effect

Citramone is a combined medicamentous drug and its therapeutic effect is due to the properties of the active components that make up its composition:

1. Paracetamol has antipyretic and analgesic properties, as well as a moderate anti-inflammatory effect.
2. Acetylsalicylic acid has antipyretic and anti-inflammatory properties, this substance also removes painful sensations caused by inflammation, and reduces blood clotting, thereby stimulating blood circulation in the focus of inflammation.
3. Caffeine produces an exciting effect on the central nervous system and stimulates the work of the psychomotor centers of the central nervous system. It increases the lumen of the blood vessels and reduces the feeling of drowsiness and fatigue. Caffeine is also known for its stimulating effect, which it produces on physical and mental activity. Possesses caffeine and a weak anesthetic effect.

Citramone increases or lowers blood pressure?

This question is often asked by patients. Due to the content of caffeine, the exciting CNS, increasing the tone and pressure, from the intake of Citramonum the pressure may also increase, despite the fact that it is contained in small doses. Moreover, you should be careful if you drink tea, cocoa or coffee and take Citramon - there is a risk of overdosing caffeine. If you have low blood pressure and a headache, then in the absence of contraindications, you can take a Citramon pill that will relieve the pain and slightly increase the pressure.

Indications for use

Basically, these are mild and moderate pains of different locations:

• headache;
• migraine;
• pain during menstruation;
• neuralgia;
• pain in the joints and muscles;
• elevated body temperature for influenza, colds and rheumatic diseases.

With strong pain, Citramon is unlikely to cope, so in more complex cases, a tool that has these effects more is recommended.

Citramon from headache

From a headache this is one of the most effective means, which usually is in the medicine cabinet. The combination of its components provides a fairly quick action - the elimination of pain, increased mental activity and efficiency. He copes with the pain of various etiologies, including migraines. Not being a narcotic drug, does not cause addiction and dependence.

It is undesirable only to mix Citramon with other drugs against headaches - these issues should be discussed with a doctor.

Contraindications

Absolute:

• glaucoma;
• hemophilia and other disorders of blood clotting;
• operations that are accompanied by heavy bleeding;
• simultaneous reception of methotrexate in an amount exceeding 15 mg per week;
• sleep disturbance, increased nervous excitability;
• deficiency of glucose-6-phosphate dehydrogenase;
• gastrointestinal bleeding or perforation;
• erosive-ulcerative lesions of the gastrointestinal tract (GIT) in the phase of exacerbation;
• peptic ulcer in anamnesis;
• hypoprothrombinemia, hemorrhagic diathesis;
• portal hypertension;
• avitaminosis K;
• chronic cardiac insufficiency III and IV of the functional class according to the classification of the New York Heart Association (NYHA);
• arterial hypertension (grade III);
• incomplete or complete combination of bronchial asthma, recurrent polyposis of paranasal sinuses and nose, as well as intolerance of non-steroidal anti-inflammatory drugs (NSAIDs), for example, ASA;
• severe hepatic and / or renal insufficiency;
• During pregnancy and breastfeeding;
• age under 18 years (with febrile syndrome) or up to 15 years (with pain syndrome);
• hypersensitivity to the components of Citramon P.

The drug is administered with caution in the following cases:

• chronic heart failure (NYHA I and II functional class);
• epilepsy, propensity to convulsive seizures;
• simultaneous reception of methotrexate in an amount of less than 15 mg per week, as well as glucocorticosteroids, NSAIDs, antiaggregants, anticoagulants, selective serotonin reuptake inhibitors;
• alcoholism;
• renal and / or liver failure of mild to moderate;
• chronic obstructive pulmonary disease;
• gout;
• cardiac ischemia;
• cerebrovascular diseases;
• diseases of peripheral arteries;
• smoking;
• elderly age.

Intended use for pregnancy and lactation

Dosage and route of administration

As indicated in the instructions for use, Citramon tablets are intended for oral administration, preferably after meals. The average therapeutic dosage for adults and adolescents over 15 years is 1-3 tablets 2-3 times a day, depending on the severity of the pain syndrome or fever.

The maximum daily dosage should not exceed 6 tablets. The drug is not intended for long-term therapy, the maximum duration of taking the tablets should not exceed 5 days.

Adverse Reactions

Side effects of Citramon:

• increased blood pressure, arrhythmia, tachycardia;
• the aggravation of heart failure, the manifestation of its secretively occuring forms (with prolonged use);
• dizziness, insomnia, agitation, anxiety, headache, tinnitus, hearing and vision impairment, aseptic meningitis;
• gastralgia, anorexia, nausea, the formation of erosion and ulcerative elements on the mucosa of the digestive canal, gastric and intestinal bleeding;
• liver failure;
• hypersensitivity reactions (including the development of the symptoms of the Fernan-Vidal triad);
• interstitial nephritis, nephrotic syndrome, necrotic papillitis, with prolonged use - renal failure;
• anemia, thrombocytopenia, leukopenia;
• acute fatty hepatosis, toxic hepatitis, acute hepatic encephalopathy (Reye's syndrome);
• development of tolerance and weak psychological dependence (with prolonged intake of high doses of the drug);
• drug headache after withdrawal of Citramon (if the drug has been used for a long time).

In animal experiments, the teratogenic effect of the drug on the fetus was also demonstrated.

Overdose Symptoms

Symptoms of overdose include nausea, vomiting, dizziness, epigastric pain. In severe cases, drowsiness, inhibition, loss of consciousness, seizures, bronchospasm, bleeding, shortness of breath.

If these symptoms appear, you should immediately seek medical help.

Treatment includes gastric lavage, enterosorbents, salt laxative. It shows forced alkaline diuresis, alkalizing agents, measures for the recovery of bcc and acid-base balance.

special instructions

Before you start using the drug, read the special instructions:

1. In patients with a predisposition to the accumulation of uric acid, taking the drug may trigger a gout attack.
2. During the intake should refrain from drinking alcohol (increased risk of gastrointestinal bleeding and toxic damage to the liver).
3. Acetylsalicylic acid slows blood clotting. If a patient is to undergo surgery, a doctor should be warned about taking the drug.
4. With continued use of the drug, control of peripheral blood and the functional state of the liver is necessary.
5. Patients with hypersensitivity or asthmatic reactions to salicylic acid and its derivatives, including acetylsalicylic acid, can be prescribed only with special precautions (in emergency services).
6. Acetylsalicylic acid has a teratogenic effect; when applied in the first trimester leads to a developmental defect - splitting of the upper palate; in III trimester - to inhibition of the ancestral activity (inhibition of Pg synthesis), to the closure of the arterial duct in the fetus, which causes hyperplasia of the pulmonary vessels and hypertension in the vessels of the small circulation. Isolated with breast milk, which increases the risk of bleeding in the child due to impaired platelet function.

Children under 15 years of age should not be prescribed medications containing acetylsalicylic acid, since in the case of a viral infection they can increase the risk of developing Reye's syndrome. Symptoms of Reye's syndrome include prolonged vomiting, acute encephalopathy, and enlargement of the liver.

Compatibility with other drugs

When using the drug, it is necessary to take into account the interaction with other drugs:

1. Caffeine accelerates the absorption of ergotamine.
2. With the simultaneous administration of the drug and alcohol-containing liquids, the risk of toxic damage to the liver increases.
3. Strengthens the action of heparin, indirect anticoagulants, reserpine, steroid hormones and hypoglycemic drugs.
4. Barbiturates, rifampicin, salicylamide, antiepileptic medicines and other stimulants of microsomal oxidation contribute to the formation of toxic metabolites of paracetamol, affecting liver function.
5. Simultaneous use with other non-steroidal anti-inflammatory drugs, methotrexate increases the risk of side effects.
6. Reduces the effectiveness of spironolactone, furosemide, antihypertensive drugs, as well as anti-arthritis drugs that promote the excretion of uric acid.
7. Metoclopramide accelerates the absorption of paracetamol. Under the influence of paracetamol T1 / 2 chloramphenicol increases by 5 times. With repeated admission, paracetamol can enhance the effect of anticoagulants (dicumarin derivatives).

Patient Reviews

We offer you to read reviews of people who used Citramon P:

1. Sasha. Citramon is a miracle pill. They help me from almost everything. The impression that the aliens came up with.. Even the records on orenirovke do. And from stress. And from a headache. And from the pain in the joints. I drink two tablets at once. About once every two weeks.
2. Tatyana. The effectiveness of Citramon is time-proved. I use it constantly: if the headache is painful, my tooth has hurt or suddenly the temperature has risen. To these tablets though and is attached the whole list of by-effects, but in practice they never appeared. The drug is really unique and universal, but the main thing is very cheap.
3. Margarita. With menstruation, I suffer from headaches, terribly sore stomach, while no pills, except Citramon, help. This is a really good medicine, it removes all the symptoms of dysmenorrhea in just a few minutes. The instructions are clear, the main thing is to strictly observe the dosage, do not exceed the course of treatment, then there are no chances.

Analogues

Structural analogs for the active substance:

• Aquacitramone;
• Ascofen;
• Acifein;
• Co-plus;
• Migrenol Extra;
• Citramarin;
• Citramon Borimed;
• Citramon P;
• Citramon Ultra;
• Citramon Lect;
• Citramone MFF;
• Citramon Forte;
• Citrapar;
• Excerdine.

Before buying an analogue, consult your doctor.

Shelf life and storage conditions

The shelf life of Citramon tablets is 4 years. They must be stored in a whole package, dark, dry, inaccessible to children at an air temperature of no higher than 25 ° C.

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