ACTS 100 description and instructions for use
The drugs of group ATSTS, created on the basis of acetylcysteine, actively entered into the practice of treatment. One of them, ACTS 100, the instruction recommends the use for children. The figure on the package indicates the dosage of the active substance. It corresponds to the minimum single dose for a child.
Forms and composition
ACTS 100 is produced by the Austrian company Hermes Pharma Gas, Sandoz Slovenia, Salutas Pharma GmbH Germany in the form of effervescent tablets or blackberry flavor. Children with pleasure drink this medicine.
In one aluminum tube contains 20 tablets or powders containing 100 mg of acetylcysteine.
The composition of the tablet and powder, according to the instructions, is 100 mg of acetylcysteine, soda, mannitol, lemon and ascorbic acid, blackberry flavor, sucrose.
Inclusion in soda makes the use of ACT 100 dangerous if a cough occurred in a patient with a sick stomach. A sucrose will require an increase in the dose of insulin for a patient with diabetes mellitus.
Acetylcysteine is the active substance of the drug.
Mechanism of action ATSTS
The instruction refers the preparation to mucolytic agents. This means that it is able to dilute sputum, mucus, pus. Studies have shown the effectiveness of acetylcysteine in three ways:
- dilution of thick secretions due to the rupture of molecular bonds of mucosaccharides, of which mucus is composed;
- stimulation of local immunity through phagocyte cells;
- antioxidant action, as an element of fighting inflammation.
The effect is manifested as much as possible within an hour after ingestion, lasting up to eight hours. ATSTS 100 decomposes in the liver, is excreted mainly with urine.
Indications for use
The instruction recommends the use of ATSTS 100 for children and adults with diseases associated with increased mucus, sputum, pus formation. Such diseases are: bronchitis, laryngotracheitis, sinusitis, inflammation of the middle ear, bronchial asthma, cystic fibrosis.
Adverse reactions occur rarely in the form of skin rashes, nausea, headache, dyspepsia, stomatitis. Patients with bronchial asthma may experience an attack of bronchospasm.
Absolute contraindications for ATSTS 100 are:
- lung diseases accompanied by hemoptysis;
- peptic ulcer of the stomach and duodenum;
- individual intolerance of components.
Not recommended reception
- for children under two years;
- during pregnancy and lactation;
- with chronic liver and kidney diseases.
The dosage and course of treatment is prescribed by the attending physician. It depends on the severity of the condition, the weight of the patient, the concomitant diseases.
For children 2-6 years of age, pediatricians recommend no more than 300 mg per day; in 7-14 years to 400 mg; for older children and adults - 600 mg per day.
An effervescent tablet or powder, according to the instructions, must be dissolved in half a cup of water, tea or juice before use. Drink after eating.
The solution must be prepared only in glass containers. When in contact with metal and rubber, acetylcysteine is decontaminated. Do not store the prepared drink for more than two hours.
ACTS 100 should not be taken concomitantly with antibiotics such as penicillin, ampicillin, erythromycin, tetracycline, with antitussive agents. Because it reduces their effect. Between ingestion of an antibiotic and ATSTS 100 should be at least two hours.
The tube with tablets ATSTS 100 should be quickly closed, because in air acetylcysteine partially decomposes.
Before beginning treatment carefully read the instructions, the way of preparation of the drink. All unexpected reactions to the medication should be reported to the doctor.
"ACC" of cough: instructions for use. "ACTS 200 reviews, price
Quite often, doctors prescribe to their patients the drug "ACC" ("ACC") for cough. Instructions on the use of this tool, as well as its contraindications, indications and side effects will be presented in this article. In addition, we will tell you about the form in which the medicine is released, what patients are saying about it, how much it costs and so on.
Packaging of the drug, its form of release, composition
Do you know, in what form do you produce the drug "ACC" ("ACC") from a cough? Instruction for use informs us that this drug is produced in two different forms. Let's consider them in more detail:
- The "ACTS" medication is a powder (granulated) intended for the duration of the preparation of the solution. This medicine should be taken only inside. One 3 gram powder bag can contain 200, 100 or 600 mg of acetylcysteine. In a cardboard bundle there are 10, 6 or 20 bags.
- The drug "ACC" - effervescent tablets. In aluminum or cardboard tubes can be 20, 10, 100 or 50 pieces. One tablet contains 600, 200 or 100 mg of acetylcysteine. As for the auxiliary components, they include citric anhydride, sodium bicarbonate, ascorbic acid, mannitol, lactose anhydride, sodium citrate, blackberry flavor and saccharin.
Pharmacological action of the drug
What is the "ACC" ("ACC") cough remedy? Instructions for use asserts that it is a mucolytic drug. In view of the fact that there are sulfhydryl groups in the structure of the acetylcysteine molecule, this causes a disruption of the disulfide bonds of mucopolysaccharides (acidic) sputum. As a result of this effect, the viscosity of the mucus visibly decreases.
The drug under consideration has a mucolytic effect, and it also facilitates the sputum evacuation due to a direct effect on its rheological properties. This drug retains its activity even in the presence of purulent mucus.
The medicine "ACC the instruction of which is presented below, is often used for preventive purposes. In this case, the severity and frequency of exacerbations in patients with cystic fibrosis and chronic bronchitis decrease.
Pharmacokinetics of the drug
What pharmacokinetic properties does the drug "ACC" have? The instruction does not contain such information. This is due to the fact that pharmacokinetic studies of this medication have not been conducted.
Medicinal preparation "ACC indications
The drug in question is administered at the following deviations:
- acute and chronic sinusitis;
- diseases of the respiratory system, which are accompanied by the formation of difficult to separate and viscous sputum (for example, bronchiectasis, acute and chronic bronchitis, cystic fibrosis, obstructive bronchitis, pneumonia, bronchial asthma and bronchiolitis);
- average otitis.
In the presence of any deviations, in no case should the medical preparation "ACTS" (powder and effervescent tablets) be prescribed? Contraindications to the use of this tool are the following conditions:
- spitting blood;
- ulcer of duodenum and stomach (especially in the phase of exacerbation);
- bleeding pulmonary;
- period of pregnancy;
- hypersensitivity to drug substances;
- the period of breastfeeding.
It should also be noted that this medication is prescribed with special caution to patients with the expansion of the veins (varicose) of the esophagus, adrenal diseases, renal and / or hepatic insufficiency.
Mode of application
How should I take ACC from a cough? The instruction for use contains the following instructions on this matter. Adolescents and adults are prescribed 200 mg three times a day. Children from 6 to 14 years of age should take the medicine 100 mg three times a day. To children from 2 to 5 years, the medication is prescribed for 1 tablet (100 mg) twice a day. With such a deviation as cystic fibrosis, a child over 6 years of age is given 2 tablets of the drug (100 mg each) three times a day. As for toddlers from 2 to 6 years, they should take a medicine of 100 mg four times a day.
Patients with a body weight of more than 30 kg with cystic fibrosis can increase the dosage to 800 mg per day.
With catarrhal diseases of short duration, the duration of therapy with the medication presented is 5-7 days. In cystic fibrosis and chronic bronchitis, the agent should be used for a longer time (for the prevention of infections).
How should I take the medicine "ACC 200"? The instruction says that this drug should be used only after eating (to avoid a negative effect on the gastric mucosa). In this case, it should be specially noted that additional fluid intake helps to enhance the mucolytic effect of the drug.
Before use, effervescent tablets should be dissolved in half a cup of plain water. The finished solution should be used immediately. In exceptional cases, it can be left for 2 hours.
If the drug is intentionally or mistakenly overdosed, the patient experiences signs such as vomiting, stomach pain, diarrhea, heartburn and nausea. To date, no serious and life-threatening side effects have been observed.
What will happen if you simultaneously take any medications and "ACC"? Experts say that combined treatment can cause a number of unwanted reactions. Let's consider them a little further.
With the simultaneous use of acetylcysteine and other antitussives, a mucus stagnant (due to suppression of the cough reflex) can occur.
During the simultaneous intake of nitroglycerin and acetylcysteine, there is a possibility of enhancing the vasodilator effect of the former.
Synergy of acetylcysteine with simultaneous use of bronchodilators is noted.
Acetylcysteine is able to reduce the absorption of penicillins, cephalosporins and tetracycline. In this regard, they must be taken inside 2 hours after the first.
Acetylcysteine is not compatible with such antibiotics as Penicillin, Erythromycin, Cephalosporin, Tetracycline and Amphotericin, as well as proteolytic enzymes.
Upon contact of acetylcysteine with rubber and metal, sulphides are formed which have a characteristic smell.
With obstructive bronchitis and bronchial asthma, the drug should be administered with extreme caution. This requires a systematic control of bronchial patency.
If after taking the medication the patient develops side effects, then stop taking the medication and immediately consult a doctor.
When dissolving any form of medicine is recommended to use glassware. It is necessary to avoid contact with rubber, metals, oxygen and easily oxidizable elements.
When treating patients with diabetes, it should be taken into account that 1 effervescent tablet corresponds to 06 XE.
To date, information on the adverse effects of the drug (in the recommended dosages) on the ability manage a car, as well as perform other activities that require special concentration of attention, no.
Shelf life and storage methods
This drug should be stored only in a dry place inaccessible to small children. In this case, the air temperature should not be above 25 ° C. Shelf life of the medicinal product is three years. At the end of this time, the use of medicines is prohibited.
After taking an effervescent tablet, the plastic or aluminum tube needs to be tightly closed.
The price and analogues of the medicinal product
The price of the tablet "ACTS" can be different, depending on the pharmacy network, as well as on the margin for the goods. However, on average, such a medicine costs about 75-150 Russian rubles. The price of granular powder is similar to effervescent tablets.
How can I replace the agent in question? In pharmacy chains there is a huge number of analogues of the drug, as well as drugs with a similar effect (expectorant, mucolytic). Among the most popular it would be desirable to allocate the following medicines: "Acestin" Acetylcysteine "Wicks Active Expectomed" Mukobene "Mukonist" Mukonex "N-AC-Ratiofarm "Fluimutsil" Exomuk 200 "Acestad" Lazolvan "Ambrobene" Ambroxol "Mukosol" Bronkatar "Solvin" Bromgexin "Gedelix" Mukaltin "Prospan" Stoptussin "Ascoril" Linkas "and other.
Patients' feedback about a medical device
Now you know what "ACTS" has analogues and what its price is. Tablets and powder for the preparation of the solution quite effectively cope with the task. This is the opinion most patients adhere to. The drug quickly treats acute and chronic sinusitis, as well as other diseases of the respiratory system. Thanks to him, viscous and difficult to separate sputum easily leaves the bronchi, significantly improving the condition of the sick person.
It should be noted and the fact that the tool in question has not only high efficiency, but also a relatively inexpensive cost. This fact is very encouraging for patients who can not afford to buy expensive medications.
ACS for cough instructions for use and dosage
Children, if they have difficulty separating sputum, as well as with a wet cough, is prescribed ACS for cough. Instructions for use and dosage of the drug are described below in the article.
ACS for cough - instruction for use and reception rules
The preparation of ACC is released in several forms, namely, in two. The first of these is a pellet in a sachet. Of these, a solution of ATSTS 100 is prepared. The second is produced in a bottle and syrup is prepared. The second kind appeared on the market. It is more preferable for children from the age of ten days of life to two years. Although the active chemicals are exactly the same.Yandex. Direct
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ATSTS from cough for children is prescribed by a doctor in the presence of a wet cough. That is, when the viscous mucus forms in the bronchi, and it is unable to retreat independently. ATSTS from cough instructions for use indicate such indications:
1. the presence of acute or chronic bronchitis;
3. bronchitis obstructive;
4. bronchial asthma;
8. chronic or acute sinusitis;
9. chronic obstructive pulmonary disease;
10. preventive reception after complications in operations;
11. poisoning with paracetamol.
Pharmacological groups of the drug ATSTS - detoxification (contains antidotes). Stimulates the motor function of the respiratory tract.
ACS for cough - dosage for use
Application and dosage of ATSTS: infants from the 10th day of life and children under two years of age take, ml syrup. Or acetylcysteine fifty mg two to three times a day (a daily dose of one hundred and fifty mg). Children from two to six years - 5 ml of syrup or (acetylcysteine one mg 2-3 times a day, three hundred mg in day); children from six to fourteen years old - 5 ml or (acetylcysteine 200 mg 2-3 times a day, four hundred mg). Observe that the child takes a lot of fluids during the day. The last dose should be no later than four hours before bedtime.
The course of treatment is five to seven days. In severe cases, the course of treatment for ATSs from cough is determined by the doctor. Syrup ATSTS calculated for 1 course of treatment.
Side effects of ATSTS: nausea, heartburn, vomiting, noise or ringing in the ears, urticaria are possible.
"ACTS" for children (syrup): instructions for use, feedback
When a child falls ill in a family, all the attention of adults focuses on it. And the point here is not whether this is a serious illness or a cold with a cough. Moreover, in fact, cough itself is a symptom of the disease and requires treatment.
To combat this problem, a lot of different medications have been developed in a variety of forms: pills, suspension, inhalants, cough syrup. "ATSTS" for children was developed by manufacturers in Germany and Slovenia. The main functions of this drug are dilution of hard-to-separate sputum, facilitating the process of removing it from the respiratory tract. "ATSTS" has an anti-inflammatory effect, suppressing pathogens developing in sputum.
Principle of work "ACTS"
For the stable functioning of the human body, nature arranged everything in such a way that in the airways constantly a special mucous secret is developed, to the basic functions of which the protective, purifying and antibacterial impact. If a person falls ill, the process of developing this secret is repeatedly activated. The consistency of this mucus has increased viscosity: the child suffers prolonged bouts of coughing, suffocates, and sputum does not depart. Such a cough is called unproductive.
It is in such cases, to help the children's body, appoint "ACTS" for children (syrup). Instruction for use allows you to assign it to children from the age of two. Viscosity of sputum directly depends on the presence in it of special bonds - disulfide bridges. "ATSTS getting into the body of the child, affects these compounds and promotes their rupture. Sputum becomes less viscous, and the process of removing it from the respiratory tract is greatly facilitated. Air masses, getting into the bronchi, can freely circulate, without causing irritation of the nerve endings. Cough becomes productive.
"ATSTS" (syrup for children) continues to be active even in those cases when a purulent component is present in the sputum. At first, parents may feel that the cough has intensified. However, the intensification of this process only indicates that the drug acts. Gradually, the cough reflex decays, and soon the cough passes completely.
The antioxidant properties of the "ACC" are able to suppress local inflammatory processes, which practically negates the likelihood of developing relapses and complications. The drug does not have any effect on the immune system.
Possible Forms of Release
Manufacturers for convenience and breadth of use offer the drug in several forms of release. The granules in the vial are diluted independently with water, an "ACTS" -syrp is obtained. Instructions for use for children often allow you to treat this medicine even for those kids who have not yet reached the age of two. However, doctors do not practice its appointment to newborns for the treatment of cough and bronchitis for the reason that the airways in infants are very narrow, and the pectoral muscles are still weak. For these reasons, a small child simply can not cough up the increased volume of sputum. If there is no alternative to this medication, then treatment with the help of "ATSTS" should be under the supervision of the treating doctor.
However, it should be noted that the "ACTS" (syrup) instruction for use for children up to a year allows you to appoint, if available in a child of cystic fibrosis (hereditary disease characterized by impaired functioning of organs respiration).
Widely used effervescent tablets "ACTS". They can be purchased in three dosages: 100, 200 and 600 mg of acetylcysteine (the main active ingredient). The dose of 600 mg is the trade name "ACTS-Long characterized by prolonged influence and prescribed to patients no younger than 14 years. One tablet of this medicine, taken once, replaces a few tricks of smaller doses.
Suspension is prepared by diluting the granules from bags (100, 200 mg) in water, tea, milk or juice. The resulting composition should not be hot. Ideally, if its temperature is close to body temperature.
With the use of "ACTS" it is even possible to do inhalations. 1-2 ml solution for injection (used in very severe cases in a hospital under by a doctor), mixed with an isotonic solution of sodium chloride and used in special inhalers or nebulizers. The procedures can be performed 1-2 times a day. The course of therapy - up to 10 days.
Indications for use
The indications for which this medication is possible are quite wide. And as for small patients, a special dosage is developed for them, called "ACTS 100". Instruction for children syrup (as an optimal form for the treatment of even infants and children under 2 years old) can be used for a variety of diseases of the respiratory system.
In general, "ATSTS" prescribed for patients suffering from bronchitis (any form: chronic, acute, obstructive), pneumonia, tracheitis, bronchitis (inflammatory processes of the lower respiratory tract), cystic fibrosis. Apply medication with bronchoekstazah (an increase in the diameter of the bronchi in the place where the bronchial wall is damaged).
Also, the appointment of "ATSTS" in the treatment of otitis and sinusitis (acute, chronic form) is practiced, since The drug is able to dilute not only phlegm, but also accumulations of pus, stimulating its elimination from organism.
Contraindications for admission "ACTS"
"ACTS" for children (syrup) instructions for use forbids patients with individual intolerance components of the medication and those who suffer from peptic ulcer of the stomach and duodenum (acute stage). These same diseases, but in the remission phase, too, can respond to the application of the "ACTS". Therefore, patients with such problems should be attentive to their own well-being.
With great care, "ACTS" (syrup for children) should be taken by patients with renal and hepatic insufficiency, in the presence of problems with the adrenal glands, with bronchial asthma.
Since many diseases are younger now, even in small children one can find peptic ulcer diseases or diabetes mellitus. At the last disease it is necessary to mean, that in structure of "ATSTS" there is a sucrose. If a child is diagnosed with phenylketonuria, then for treatment of a cough you have to choose "ACTS which does not include aspartame (sweetener).
Contraindication for "ATSTS Long" - the age of a child under 14 years.
Methods of application and dosage
Instructions for the use of "ATSTS 100" for children syrup are recommended for admission when the patient's age is from 2 to 5 years. Also it can be granules in bags (volume - 100 mg), which take 2-3 times during the day. Another option is the granules in the vial for the production of syrup, which is shown to be taken by 5 ml (1 measuring spoon) also 2-3 times during the day after eating.
Patients of the age group from 6 to 14 years old practice the appointment of "ATSTS" 200 mg (granules in bags) twice a day or 2 measuring spoons (10 ml) of syrup twice a day during meals.
Patients over 14 years of age practice the appointment of "ATSTS" in 2 scoops (10 mg) 2-3 times during the day (or use "ACTS Long").
In the most extreme cases, you can use the "ACTS" (syrup) instruction for children for up to one year. In this case, medical experts say that there is still insufficiently developed respiratory system and weak pectoral muscles. A small child will find it difficult to cough up an increased amount of sputum.
It is worth mentioning that the above described standard treatment regimen. In some particularly severe cases, the dosage of the drug can be adjusted upwards (or reduced if the situation is not very severe). The usual course of treatment is up to 7 days. Only the doctor can decide to increase the treatment period. In chronic forms of bronchitis or cystic fibrosis, a course of therapy with the use of "ATSTS" can last for several months. In parallel, ongoing monitoring of the functioning of the liver, kidneys, adrenals. The parameters of blood enzymes are also subject to control.
Possible side effects
Side effects of the drug "ACTS" is rare. Parents of small patients talk about the occurrence of headaches, the development of stomatitis, noise in the ears. Significantly, there are abnormalities in the functioning of the digestive tract, such as nausea, vomiting, diarrhea.
Also, among the possible negative manifestations in the application of the "ACTS" for children (syrup), the instruction for use informs about the risk of lowering blood pressure, about the development of tachycardia (heart palpitations), bronchospasm, the appearance hives.
In case of occurrence of any negative reactions during the therapy with the use of "ATSTS" it is necessary to stop taking the medication and without fail to consult a pediatrician.
Exceeding the permissible dosage
An overdose of the drug "ACTS" can occur in several cases. It is possible for a child to take a dose calculated for an adult patient, use the medicine in an overestimated volume without special instructions from the doctor or Accumulation of it ("ATSTS") in the body, which is possible with a long course of treatment without proper monitoring of the liver, kidneys, indicators blood. In any case, the possible instructions for patients to respond to "ATSTS" (for children - syrup) instructions for use describe such manifestations as a drop in blood pressure, nausea, vomiting, a feeling of dry mouth. Also, there is a possibility of the appearance of allergic dermatitis, accompanied by a rash and skin pruritus, bronchospasm may develop.
In especially severe cases, doctors speak of the possibility of angioedema and shock.
Interaction with other drugs
All information on possible drug interactions contains for the "ACTS" (syrup) instructions for use. For children from the year, you can take it only in the most extreme cases and under the supervision of a doctor. Although with the parallel application of the "ATSTS" with something else, there is danger for patients of any age.
There is information on the incompatibility of the main active substance "ACC" with semisynthetic penicillins, cephalosporins, aminoglycosides. On the contrary, there is no information on the incompatibility of acetylcysteine with antibacterial drugs such as Amoxicillin, Erythromycin, and Cefuroxime.
What should I pay attention to?
As mentioned earlier, doctors usually prefer "ACTS 100" (syrup) for treating patients from 2 to 5 years old. Instructions for use for children, reviews of pediatricians warn parents about the inadmissibility of joint admission of "ATSTS" and any antitussive medications. At such a parallel reception, "ACC" dilutes sputum, and antitussives suppresses cough reflex, sputum does not expectorate. This is fraught with stagnation of phlegm, which seriously threatens the health, and sometimes the life of the child.
Pediatricians also do not prescribe "ATSTS" together with antibacterial agents, as they may be incompatible. Only a few types of antibiotics of tetracycline, penicillin and cephalosporin series can be used together with "ATSTS" with intervals of at least 2 hours between doses.
Independently to plant granules and powders of "ATSTS" is permissible only in glassware. It is recommended not to allow contact with rubber or metal.
When treating with the use of "ATSTS" it is required to increase the volume of consumed liquid. This will greatly enhance the mucolytic effect of the drug. Children should take "ACTS" no later than 4 hours before bedtime.
Opinion of consumers about the drug
Parents of patients are satisfied with the drug "ACTS" (syrup). Instructions for use for children (consumer reviews confirm this fact) gives clear instructions on the method of application of the drug, dosage. Cough in children usually very quickly becomes productive and passes for 3-4 days. T. e. means effectively in almost 100% of cases.
The syrup has a pleasant orange flavor, so even the most capricious patients do not have to be forced to take the medicine for a long time. In addition, the cost of ATSTS is available to a wide range of consumers with a wide range of financial opportunities. The product is very convenient in storage, it will not be difficult to take it with you on the road.
The "ACTS of course, has certain contra-indications and side effects, but its application only on appointment of a doctor and adherence to all recommendations will save most of the unpleasant consequences and manifestations.
The child will be deep and calm breathing, and parents will not worry about his well-being.