Vinpocetine

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Vinpocetine improves the metabolism and blood flow of the brain.

Increases the level of catecholamines in the brain tissue. This action is achieved through an integrated mechanism. The drug intensively and selectively increases the cerebral fraction of the minute volume of blood and improves blood circulation the brain as a whole, reduces the resistance of the cerebral vessels, without affecting the parameters of the general circulation.

On this page you will find all information about Vinpocetin: the full instructions for use on this medication, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already used Vinpocetine. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

A drug that improves blood circulation and brain metabolism.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much is Vinpocetine? The average price in pharmacies is at the level of35 rubles.

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Form of issue and composition

The drug is available in the form of tablets, concentrate for the preparation of solution for injection and a ready-made solution for intravenous administration. The main active ingredient is vinpocetine, its content in one unit of each dosage form is:

  • In the tablet - 5 mg;
  • In ampoules with concentrate and solution for injection - 10 mg.

Vinpocetine tablets are white, round, on one of the flat surfaces - engraving the name of the manufacturer's company, on the other - the dividing risk.

Excipients: magnesium stearate, talc, low molecular weight cellulose, lactose.

The solution for intravenous administration is a clear, slightly colored liquid, which includes auxiliary components: ascorbic acid, sodium pyrosulfite, sorbitol, tartaric acid, benzyl alcohol, water for injection.

In the pharmacy chain Vinpocetin enters:

  • Blisters of 25 tablets in cardboard packs, 25, 50 pieces each;
  • Ampoules of dark glass 2 ml each in cell packs, 5, 10 pieces each.

Pharmacological effect

Vinpocetine has nootropic, neurometabolic and cerebral blood-improving properties. The mechanism of action of the drug consists of several components: it improves the metabolism and cerebral blood flow, has a positive effect on the rheological parameters of the blood.

Reduces cerebral vascular resistance and selectively increases cerebral blood flow, but does not have a significant effects on blood pressure, heart rate, cardiac output, OPSS (systemic blood circulation indicators); does not cause the effect of "stealing".

Vinpocetine improves microcirculation in the brain, due to inhibition of platelet aggregation and reverse capture adenosine, increase the deformability of erythrocytes, reduce blood viscosity; provides the transition of oxygen into cells.

Indications for use

What helps Vinpocetine? Indications for use in the drug are:

  1. Otology: deterioration of hearing toxic (incl. medication) or vascular genesis, dizziness of labyrinth origin, idiopathic noise in the ears, cochleovestibular neuritis, Meniere's disease, senile hearing loss.
  2. Neurology: acute and chronic insufficiency of cerebral circulation (mental and neurological symptoms of cerebral circulation, posttraumatic and hypertensive encephalopathy, ischemic stroke, multi-infarct dementia, transient ischemia, post-stroke state and craniocerebral trauma, cerebral artery atherosclerosis, vertebrobasilar insufficiency).
  3. Ophthalmology: vascular diseases of the eyes caused by angiospasm of the choroid and retina (including secondary glaucoma, degenerative diseases of the choroid, macula or retina; venous and arterial embolisms or thromboses).

Contraindications

  • Pregnancy;
  • Hypersensitivity to the components of the drug.

For parenteral use of Vinpocetin additionally contraindications are:

  • Severe forms of arrhythmia;
  • Severe ischemic heart disease.

There are no data on the safety of the use of lactating women.

Application in pregnancy and lactation

The drug is prohibited for use during pregnancy (because of the riskplacental bleedingand suddenabortionas a result of stimulation of placental blood supply) and during lactation.

Instructions for use

The instructions for use indicate that Vinpocetine is taken 3 times a day for 5-10 mg. The initial daily dose is 15 mg, the maximum is 30 mg.

The drug in the form of injections is most often used in acute conditions in a single dose of 20 mg. With good tolerability for 3-4 days, the dose is increased to 1 mg / kg.

The duration of therapy is 10-14 days. In the process of cancellation, the dosage of the drug should be reduced gradually. A year is allowed no more than 2-3 courses of taking the drug.

Side effects

It is very important to familiarize yourself with such reactions before starting the use of the drug. Among the side effects are the following:

  1. GIT: nausea, rarely vomiting, debilitating heartburn, belching, dry mouth.
  2. Endocrine system: activation of sweat glands is possible, which is manifested by excessive sweating.
  3. CNS: frequent migraines, dizziness, weakness are possible. Very often there are violations of sleep: it can manifest as insomnia or, conversely, drowsiness. Some patients may note the appearance of pain in the lumbar region.
  4. CAS: rapid heart rate (tachycardia), hypotension (lowering blood pressure). Conductivity between the ventricles of the heart slows down, a disruption of the normal functioning of the contractile mechanism.
  5. External manifestations: skin hyperemia (mainly face - it is red and hot to the touch). When injecting a drug, thrombophlebitis may develop at the site of the injection.

It is also possible to develop an allergic reaction to the constituent components of the drug.

Overdose

Overdose is possible only in case of incorrectly selected dose, since it occurs when using at least 30 mg. preparation per day. In such a situation, it is required to wash the stomach with saline solution. Next, doctors advise drinking activated charcoal in the ratio of 1 tablet per 10 kg of weight and see a doctor.

special instructions

The drug is used with caution in arrhythmia, angina, with unstable blood pressure and reduced vascular tone. Parenteral administration is recommended in acute cases, for example. After improving the clinical picture of the patient transferred to the reception inside.

In hemorrhagic cerebral stroke, parenteral administration is permissible only after the reduction of acute events (usually 5-7 days).

Drug Interactions

The medicine "Vinpocetine" can be used simultaneously with "Digoxin", "Glibenclamide", "Imipramine", "Hydrochlorothiazide" and β-adrenoblockers. Decrease in pressure is observed when combined with Methyldopa.

Caution should be observed in conjunction with anticoagulants, antiarrhythmic drugs. Together with "Heparin" the agent increases the probability of hemorrhagic abnormalities.

Reviews

We picked up some feedback from people about the Vinpocetin preparation:

  1. Zina. Previously, I took this drug, helped, and increased efficiency. It's been 2 years. Again felt bad, strong dizziness. I'll try to take it again.
  2. Pauline. Vinpocetine prescribed the doctor to my old grandmother. She had constant headaches and dizziness, hypertension, memory disorders and even consciousness. It was hard to look at her suffering and the fact that she does not remember anything and nobody is confused. But vinpocetin returned her to a normal state and consciousness, more or less normalized the pressure. Unfortunately, hearing and sight, unfortunately, did not improve.
  3. Galina. Carried out a course of treatment in the form of a dropper: Actovegin, Cerepro and Vinpocetine. Previously, Cavinton was dripping. They replaced me without warning. Turned about the noise in the head and ears, and problems with hearing (neurosensory hearing loss). I have a number of diseases: Chronic cerebral ischemia, cerebral atherosclerosis, hypertension, angina pectoris, arterial hypertension, arrhythmias, atrial fibrillation, osteochondrosis, dorsopathy cervical spine, intervertebral hernia, etc. After treatment, health deteriorated: heart pain, severe head compression and headache, numbness in the hands, weakness and noises.
  4. Marina. All summer, I missed with dizziness, a severe headache. The forces were no longer tolerated. I did not want to contact the doctors, they only know how to write out the certificates. But somehow one pharmacist advised me to try Vinpocetin. Initially, I did not feel the result, because I threw all the pills together. But then I noticed that after taking this little pill my head was not spinning. Began to take regular. The headache did not go away, but even if there is not so much dizziness, blood and oxygen get better in the brain, for which I am very grateful to this drug!
  5. Alexey. I was prescribed Vinpocetin to speed recovery after a stroke. After drinking 10 capsules, I felt a noise in my ears. Has addressed to the doctor, he has told or said, that such reaction of an organism to reception of a medicine is normal. After a couple of days he lost consciousness. The ambulance doctor reported that this remedy is causing a decrease in pressure. I do not recommend it to hypotension.

In general, reviews about Vinpocetine Acry and Vinpocetine Forte and Vinpocetine are fundamentally similar and characterize the therapeutic properties of these drugs. Most often the drug is used to improve the blood supply to the brain. Comments of doctors at the forum indicate a rare occurrence of side effects and recommend starting the drug only on the appointment of a medical professional. Children this drug is prohibited.

Analogues

Vinpocetine analogues of the active substance are the following medicines: Bravinton, Vincetin, Cavinton, Telectol, Korsavin. These Vinpocetin analogues are not prescribed to children under 18 years of age.

Also, if necessary, after consulting a doctor, you can pick up medicines with a similar mechanism of action in various dosage forms:

  • Tablets and capsules - Amilonosar, Bilobil, Ginkoum, Vinpotropil, Gingium, Gopantam, Nootropilum, Ginos, Fezam, Noben, Idebenon, Karnitsyn, Lucetam, Memotropil, Pantokaltsin;
  • Tablets are sublingual - Glycine-Bio, Glycine Ozone, Glycine-Bio Pharmaplant;
  • Solution for injection - Amilonosar, Nootropil, Pikamilon, Pyracetam, Cerebrolysin;
  • Solution for oral administration - Demanol, Coguitum, Ceraxon, Tanakan;
  • Nasal drops - Minisem, Semax;
  • Syrup - Pantogam.

Before using analogues, consult your doctor.

Storage conditions and shelf life

Vinpocetine can not be stored for longer than 5 years from the date of release. Tablets and ampoules should be kept in a dry place inaccessible to children and sun rays. The air temperature should not exceed 35 ° C.


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