Arthraldol: instruction on the use of injections and tablets

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Content

  • 1Arthradol
    • 1.1Composition
    • 1.2Form of issue
    • 1.3pharmachologic effect
    • 1.4Pharmacodynamics and pharmacokinetics
    • 1.5Indications for use
    • 1.6Contraindications
    • 1.7Side effects
    • 1.8Instructions for use (Method and dosage)
    • 1.9Interaction
    • 1.10Terms of sale
    • 1.11Storage conditions
    • 1.12Shelf life
    • 1.13Analogues of Artradol
    • 1.14Children
    • 1.15In pregnancy and lactation
    • 1.16Reviews of Artradol
    • 1.17Price Arthadol, where to buy
    • 1.18WER.RU
    • 1.19ZdravZona
    • 1.20IFK Pharmacy
  • 2Prisms of Artradol: instructions for use for the treatment of joints
    • 2.1Clinical and pharmacological group
    • 2.2Conditions of leave from pharmacies
    • 2.3Price list
    • 2.4Form of issue and composition
    • 2.5Pharmacological effect
    • 2.6Indications for use - instructions
    • 2.7Application in pregnancy and lactation
    • 2.8Instructions for use Artradol
    • 2.9Side effects
    • 2.10Overdose of the drug
    • 2.11special instructions
    • 2.12Drug Interactions
    • 2.13Reviews
    • 2.14Analogues
    • 2.15Storage conditions and shelf life
  • 3Artradol nyxes: instructions for use
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    • 3.1Dosing and Administration
    • 3.2Pillows
    • 3.3Analogues of injections of Artradol
    • 3.4Terms and conditions of storage
    • 3.5Prices for injections Artradol
  • 4Instructions for the use of Artradol
    • 4.1Information about the manufacturer, the form of release and action of the drug
    • 4.2Dosage and route of administration
    • 4.3Lyophilizate
    • 4.4Ointment
    • 4.5special instructions
    • 4.6Interaction with drugs
    • 4.7Storage and dispensing from pharmacies
  • 5Artradol instructions for use and analogues
    • 5.1The basic description of the preparation
    • 5.2Pharmacological features of the agent
    • 5.3Indications and contraindications for use
    • 5.4How to apply the medicine
    • 5.5Features of the drug
  • 6Artradol: instructions for use, reviews
    • 6.1Composition and form of release
    • 6.2pharmachologic effect
    • 6.3Indications for prescription
    • 6.4Application and dosage
    • 6.5Artradol: instructions for use, reviews, analogues
    • 6.6special instructions

Arthradol

Composition

The preparation has in the composition of 100 mgchondroitin sodium sulphate.

Form of issue

The medicine is issued in the form oflyophilizate, which is used to prepare a solution for intramuscular administration.

Ampoules contain 2 ml of the drug.

The cardboard box contains one cardboard holder, containing 10 ampoules or two plastic pallets, each containing 5 ampoules.

LyophilizateIs a white or yellowish porous mass that is compacted into tablets.

Also, an ointment of Artradol 5% is used, which is applied externally. It is sold in cans of glass to 30 grams, packed in a pack of cardboard.

pharmachologic effect

Active substancechondroitin sulfateis the main component of proteoglycans, which together with collagen fibers form a cartilage matrix. The drug has chondroprotective properties.

It has the ability to reduce the activity of enzymes, which provoke the processes of degradation of articular cartilage.

Also, under its influence, the production of chondrocytes by proteoglycans is stimulated and metabolic processes in cartilage and subchondral bone are intensified.

Artradol promotes metabolismcalciumandphosphorusin the cartilaginous tissue, promotes its active regeneration, takes part in the formation of cartilaginous and bone tissue.

The medicine has analgesic and anti-inflammatory properties.

Under the influence of the drug decreases the release of mediators of inflammatory processes, reduces the level of secretion of prostaglandin E2 and leukotriene B4.

Thus, Artradol activates resistance to restorative processes in cartilaginous surfaces of joints, normalizes the production of articular fluid, does not allow the collapse connective tissue. Due to this effect, the level of pain is reduced, the mobility of the joints improves.

In view of the structural similarity withheparinthe drug is able to potentially prevent the appearance of fibrin clots in the subchondral and synovial microcirculatory bed.

Pharmacodynamics and pharmacokinetics

Absorption and distribution of chondroitin sulfate occurs when administered intramuscularly easily.

Half an hour after the introduction, the drug can already be detected in the blood in high concentrations, after 15 minutes the drug is found in the synovial fluid.

The maximum concentration is noted one hour after the administration, for two days the active substance content gradually decreases. Artradol mainly accumulates in the cartilaginous tissue.

The drug is excreted through the kidneys for one day.

Indications for use

Pricks of Artradol are prescribed for the following diseases:

  • primary arthrosis;
  • degenerative-dystrophic diseases of the spine, joints;
  • osteoarthritis, in which large joints are affected;
  • intervertebralosteochondrosis.

Contraindications

The drug is not used in the following cases:

  • high sensitivity to its components;
  • the child's age of the patient.

Very carefully, the remedy is given to people who are prone to bleeding; patients withthrombophlebitis; during pregnancy and lactation.

Side effects

When using the drug, such side effects are rarely noted:

  • allergic manifestations;
  • hemorrhages in the place where the injection was conducted.

Instructions for use (Method and dosage)

The instruction for Artradol is as follows: the injections are administered to the patient intramuscularly, the agent is given 100 mg every other day.

If the drug is well tolerated, then after the third injection, the dose may be increased to 200 mg. A total of 25 to 35 injections are prescribed for treatment. Repeat the course of therapy can be in six months.

How long should the repeated course of therapy continue, the attending physician determines in each individual case.

Instructions for the use of Artradol provide that, before the direct administration, the contents of the ampoule must be dissolved in 1 ml of water for injection.

Interaction

If Artradol is taken simultaneously with the indirectantiaggregants, anticoagulants, fibrinolytic, the effect on the body of these drugs may be intensified. In this case, it is necessary to monitor the coagulability of the blood.

Terms of sale

It is released on prescription.

Storage conditions

Store Arthraldol in a dark place, and the temperature should not exceed 25 ° C. It is necessary to protect the remedy from children.

Shelf life

You can store drugs for 3 years.

Analogues of Artradol

Preparations that contain a similar active substance are analogues of the drug, but they can still act on the body somewhat differently. Therefore, independently, without prior consultation with a doctor, one should not replace Arthradol with anything.

Nevertheless, in the pharmacy network a lot of money is being realized -chondroprotectors, which also contains chondroitin sulfate, for example,Chondrolon, Honsurid, Alflutopand etc.

The price of analogues is generally higher.

Children

For the treatment of children is not applied, because there is not enough clinical data on its effect.

In pregnancy and lactation

Pregnant women and lactating mothers are prescribed with caution.

Reviews of Artradol

At forums, reviews about Artradol are relatively common. In particular, reviews of patients with spine ailments, etc. testify that the injections significantly reduce the pain syndrome already during the first course of therapy.

According to the patients, the drug effectively reduces edema in patients with osteochondrosis, joint arthrosis.

Positive in general, and reviews of doctors, which noted that the drug works most effectively, if you use it strictly according to the scheme and in the dose that the specialist appointed.

In the reviews, very little is said about the side effects of the remedy. Sometimes people who have been treated with the drug mention minor allergic reactions, as well as the appearance ofhemorrhagesin the places where the injection was conducted.

Price Arthadol, where to buy

The price of Artrudol injections in Russia now averages between 720 and 850 rubles (10 packs). In different cities, the price of a medicine may be slightly different. For example, you can buy a drug in Moscow at a price of about 700 rubles. (10 pieces.).

The price of Artradol in Ukraine is approximately 500 - 620 hryvnia for 10 ampoules. Ointment Artradol costs about 100 rubles. Artdolol tablets are not available.

In Belarus, the drug is not registered, so you can buy the drug in Minsk only on advance order.

  • Online pharmacies in RussiaRussia

WER.RU

  • Arthralol lyophilizate 100 mg 2 ml 10 pcs.

ZdravZona

  • Arthralol lyophilizate for a solution of 100mg No. 10 ampoules

IFK Pharmacy

  • ArtradolBiok - Kursk biofactory (the city of. Kursk), Russia

NOTE! Information about medicines on the site is a reference-generalizing, collected from public sources and can not serve as a basis for making a decision about the use of medications in the course of treatment. Before using the drug Arthraldol necessarily consult with your doctor.

A source: http://medside.ru/artradol

Prisms of Artradol: instructions for use for the treatment of joints

Artradol is a chondroprotector with the ability to restore the cartilaginous structure.

The drug is prescribed for the treatment of osteochondrosis, arthrosis and other pathologies of the spine and joints. It eliminates the main symptoms of the disease, strengthens the human musculoskeletal system.

On this page you will find all information about Artradol: the full instructions for use for this medicine medium, average prices in pharmacies, complete and incomplete analogs of the drug, as well as reviews of people who have already applied Artradol. Want to leave your opinion? Please write in the comments.

Clinical and pharmacological group

A drug that regulates metabolism in cartilage tissue. Chondroprotector.

Conditions of leave from pharmacies

It is released on prescription.

Price list

How much does Artradol cost? The average price in pharmacies is at the level of 680 rubles.

Form of issue and composition

Artradol is available as a lyophilizate, which is used to prepare a special solution for intramuscular administration. In this case, one such lyophilisate contains in its composition 100 mg of active substance, i.e., chondroitin sulfate.

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Pharmacological effect

In the lyophilisate Arthragol there is only one active substance - chondroitin sulfate. This drug is an analogue of our cartilage protein.

After entering the body, chondroitin is delivered by blood to the joint cavity. There, the medicine will produce a curative effect:

  1. It inhibits the degeneration of cartilaginous tissue in various diseases.
  2. It leads to the formation of new proteins and amino acids, normalizes protein metabolism in the cartilage.
  3. Stimulates the formation of the intercellular substance of the cartilage.
  4. Improves the exchange of calcium and phosphorus in the locus of action.
  5. Block enzymes that contribute to tissue damage.
  6. Reduces the intensity of inflammation.
  7. Increases mobility in damaged joints.
  8. Strengthens the regeneration and production of joint fluid.
  9. Slows the damage to bone tissue due to mineral deficiency and inflammation.
  10. With prolonged use reduces pain in the joint.

Concentration in the articular cavity of chondroitin reaches a maximum after 3-4 hours after administration. However, its effect is associated with long biochemical processes.

Indications for use - instructions

The instructions for use indicate that Artradol is prescribed to patients in the case of diagnosis:

  • arthrosis in the initial stage;
  • spondyloarthrosis, if the pathology has spread to soft tissues;
  • osteoarthritis (the drug complements complex therapy);
  • osteochondrosis, accompanied by dystrophy of the spine and (or) a violation of their depreciation.

Contraindications

Do not use the drug in such cases:

  • Use in children of childhood;
  • Individual intolerance or hypersensitivity to Artradol or its components.

Use with caution:

  • Application during pregnancy;
  • Application during breastfeeding;
  • The presence of bleeding in patients;
  • Increased patient addiction to bleeding;
  • The presence of vein thrombosis in patients.

Application in pregnancy and lactation

The drug is administered with caution in pregnancy and lactation.

Instructions for use Artradol

The instructions for use indicate that the injections of Artradol are given in / m at 100 mg every other day. Before use, the contents of the ampoule are dissolved in 1 ml of water for injection. With good tolerability, the dose is increased to 200 mg, starting with the 4th injection.

The course of treatment is 25-35 injections. Repeated course - after 6 months. The duration of repeated courses of treatment is set by the doctor.

Side effects

Artradol is well tolerated in the vast majority of cases, but side effects after its use are still possible.

With increased sensitivity to the components of this drug, its use can lead to allergic reactions.

In rare cases, the appearance of hemorrhages at the injection site.

Overdose of the drug

There is no information about an overdose of the drug at this time. When combined, there is the possibility of enhancing the properties of indirect anticoagulants, antiplatelet agents, fibrinolytic agents. Pregnant and lactating women Artradol should be administered with extreme caution.

special instructions

The instructions of Artradol prescribe with caution to take it:

  • pregnant women and nursing mothers;
  • people who have a peptic ulcer.

It should exclude the reception of any alcoholic products in the first hours following the injection. In the presence of pathologies of the kidneys / liver, the medication should be accompanied by regular monitoring of the condition of these organs.

Drug Interactions

The use of the drug in parallel with indirect anticoagulants, fibrinolytic or antiplatelet agents will require more frequent monitoring of blood coagulability.

Reviews

At forums, reviews about Artradol are relatively common. In particular, reviews of patients with spine ailments, etc. testify that the injections significantly reduce the pain syndrome already during the first course of therapy.

According to the patients, the drug effectively reduces edema in patients with osteochondrosis, joint arthrosis.

Positive in general, and reviews of doctors, which noted that the drug works most effectively, if you use it strictly according to the scheme and in the dose that the specialist appointed.

In the reviews, very little is said about the side effects of the remedy. Sometimes people who have been treated with the drug mention minor allergic reactions, as well as the appearance of hemorrhages in the places where the injection was done.

Analogues

Analogues of Artradol according to the active substance are preparations:

  • Arthra;
  • Artra Chondroitin 750;
  • Mukosat;
  • Structum;
  • Hondrogaard;
  • Chondroitin-AKOS;
  • Chondroitin-Ferein;
  • Chondroitin-Verte;
  • Chondroxide;
  • Chondrolife lyophilizate;
  • Chondrolon lyophilizate;
  • Chondroitin.

Analogs of Artradol for the mechanism of action and membership in a single pharmacological group include:

  • Actasulide;
  • Amtolmethine guacyl;
  • Amoeolin;
  • Aminoarthrin;
  • Aponil;
  • Arthrodarin;
  • Артрокер;
  • Aulin;
  • Vipraxin;
  • Glucosamine;
  • Glucosamine;
  • Diaflex Rompharm;
  • Diacerein-Mac;
  • Don;
  • Coxtral;
  • Movageyn;
  • Nyz;
  • Naisylate;
  • Nimesan;
  • Nimesil;
  • Nimesulide;
  • Nimika;
  • Nimulid;
  • Prolid;
  • Sustilac;
  • Elbona.

Before using analogues, consult your doctor.

Storage conditions and shelf life

The drug should be stored in a dry, protected from light, out of reach of children at a temperature of no higher than 20 ° C. Shelf life - 3 years.

A source: http://simptomy-lechenie.net/ukoly-artradol/

Artradol nyxes: instructions for use

Artradol is a domestic preparation based on chondroitin, which has a chondroprotective effect that stimulates the formation and restoration of the cartilaginous and bony tissue of the joint.

Chondroitin displays the following pharmacological effects:

  • is the main component of hyaline tissue and actively participates in its formation and recovery;
  • normalizes the exchange of phosphorus and calcium in cartilage and bone tissue;
  • blocks the negative effects of lysosomal enzymes and free radicals that destroy the structure of the cartilage and disrupt its function in the joint;
  • reduces the intensity of degenerative and destructive processes of hyaline, improves metabolism in it;
  • helps restore the surfaces of the cartilage and joint, as well as the articular bag;
  • prevents compression of the joint tissues;
  • Increases the production and viscosity of synovial fluid, which improves joint mobility and reduces pain;
  • stimulates the synthesis of hyaluronic acid, strengthening the connective tissue of the joint and periarticular tissues;
  • inhibits the resorption of bone, reduces the decrease in calcium in its composition;
  • restores bone tissue and reduces the severity of symptoms and further progression of osteoarthritis;
  • exhibits analgesic and anti-inflammatory effect, significantly reduces the severity of the pain syndrome in the joint and its puffiness;
  • reduces the consumption of non-steroidal anti-inflammatory drugs;
  • can prevent the formation of thrombi in the microcirculatory bed of the joint tissues due to the similarity with heparin in structure.

Since the drug has an ampoule form and is administered intramuscularly, it is necessary to prescribe and prescribe a doctor for its use.

Form of issue and composition

Artradol is available in ampoules of 2 ml. It is administered by intramuscular injection. Inside the ampoule is a white porous mass, formed in the form of a tablet.

The package contains 10 ampoules.

The composition of the medicinal product includes:

Indications for use

Indications for the use of Artradol are degenerative and dystrophic diseases of the peripheral joints and spine:

  • deforming, posttraumatic, rheumatic osteoarthritis;
  • spondylarthrosis of the cervical, thoracic or lumbar spine;
  • chronic osteoarthritis;
  • intervertebral osteochondrosis;
  • painful sensations in acute and chronic diseases of the musculoskeletal system;
  • pains that occur against the background of degeneration of the joint tissue;
  • infection of joints and bones;
  • various local osteopathies;
  • non-growth of bone fracture, delayed formation of bone callus.

Contraindications

Artradol is contraindicated:

  • at hypersensitivity reactions on acting or auxiliary substances included in the composition;
  • bleeding of various etiologies and a tendency to bleeding;
  • thrombophlebitis;
  • in the period of pregnancy and lactation;
  • children's age due to lack of clinical data.

Dosing and Administration

The drug is administered intramuscularly every other day through 1 ampoule. If necessary, the administered dosage of the drug can be increased to, g (2 ampoules of 100 mg).

To obtain a solution for injection, the ampoule is diluted with 1 ml of sterile water d / injection. The course of treatment is selected individually depending on the course of the disease, most often it is 25-35 ampoules.

Pillows

Arthraldol can cause allergic reactions, such as pruritus, urticaria, dermatitis, as well as bleeding at the site of administration of the drug.

Analogues of injections of Artradol

Similar preparations are:

  • Chondrolon is a preparation of chondroitin with a similar dosage and form of release. Manufacturer of the medicinal product: Microgen NGO FSUE (Immunopreparat), Russia;
  • Chondroitin sulfate is also available in the form of ampoules with a dosage, g. Manufacturer: Ellara Ltd., Russia;
  • Mucosate is available in ampoules of 1 and 2 ml, the dosage is 100 mg / ml. The manufacturer of the medicinal product: Synthesis OJSC, Russia;
  • Chondroguard is available in ampoules of 1 and 2 ml, the dosage is 100 mg / ml. The manufacturer of the medicinal product: Soteks FarmFirma, Russia.

Terms and conditions of storage

The shelf life of Artradol is 3 years. After the expiration of this period, the use of the medicinal product is prohibited. Keep the drug in a place inaccessible to children, in a temperature regime of no higher than 25 degrees.

Prices for injections Artradol

Arthralol lyophilizate for solution for intramuscular injection 100 mg, 10 pcs., Ampoule 2 ml - from 697 rubles.

Estimate Arthradol on a 5-point scale:

(51, the average rating is 3.4118f5)

A source: http://bezboleznej.ru/artradol

Instructions for the use of Artradol

Pricks of ArtradolUsed for the treatment of joint pathologies and diseases of the spine.

In addition, they are well proven in the rehabilitation period after the fractures suffered.

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Information about the manufacturer, the form of release and action of the drug

In Russia, the medicine is produced:

  1. FKP "Kursk Biofactory-Firm" BIOK
  2. FKP "Armavir Biological Factory".

The basis of the drug ischondroitin sulfate. This substance performs several functions:

  • optimizes the phosphorus-calcium metabolism that occurs in the cartilaginous tissue;
  • resistance to enzymes that destroy the structure of the articular cartilage;
  • accelerates the regeneration of bone tissue;
  • due to analgesic and anti-inflammatory effect reduces the need for a person to take non-steroid drugs;
  • stimulates the production of intra-articular fluid;
  • increases the mobility of the joint.

Medicines, the action of which is directed to the treatment of joint pathologies, is denoted by the term "chondroprotectors".

Preparation Arthradolis available in 2 forms.

Liofilizat - this dehydrated drug, tamped in a pill or in powder form.

Dosage and route of administration

Lyophilizate

In 1 ml of water for injection dissolve the contents of the ampoule. The drug is intended for intramuscular injections, at the rate of 100 mg (the contents of 1 ampoule) per day.

The injections are done every other day.

The average duration of treatment is 30 injections. If the patient is noted for good tolerance to the drug, then, starting from the 4th injection, the daily dose is increased to 200 mg. After six months, the course of treatment can be repeated.

Decide on the appointment of any chondroprotectors, the right dosage and the re-appointment of a course of treatment should only be a doctor!

Ointment

The agent is used externally 1 - 2 times a day, applying a thin layer on the skin in the projection of the affected area.

If you do not know if you are not hypersensitive to the composition of the drug Artradol, you should apply a small amount of funds to the delicate skin of the inner flexion of the elbow.

Appearing burning, rash or redness indicates that you are allergic to ointment, which means you can not use it. You should also do this before using other medicines that are available in the form of a gel, paste.

Indications for use

The instructions for use indicate thatArthralol is prescribed to patients in the case of diagnosis:

  • arthrosis in the initial stage;
  • spondyloarthrosis, if the pathology has spread to soft tissues;
  • osteoarthritis (the drug complements complex therapy);
  • osteochondrosis, accompanied by dystrophy of the spine and (or) a violation of their depreciation.

Contraindications

  1. Because of the lack of information about the effect of the drug on the health of children, it is not assigned to persons under 18 years of age.
  2. Allergy to the components of the composition is also the basis for drug discontinuation.

special instructions

Instruction of Artradolprescribes with caution to accept it:

  • pregnant women and nursing mothers;
  • people who have a peptic ulcer.

It should exclude the reception of any alcoholic products in the first hours following the injection.

In the presence of pathologies of the kidneys / liver, the medication should be accompanied by regular monitoring of the condition of these organs.

Side effects and overdose

Scientists EULAR (European League against Rheumatism) conducted a study of the toxicity of chondroitin sulfate. The results of the work allowed them to assign the substance to the 6th place. And this is on a scale of 1 to 100! Apparently, the remedy is practically safe.

Observations of patients indicate the lack of information about overdose and serious complications. Everything is limited by local allergic reactions.

Interaction with drugs

Strengthens the effect of taking antiplatelet agents, anticoagulants and fibrinolytics. This feature manifests itself in a change in the patient's blood picture and requires regular monitoring by a doctor.

Storage and dispensing from pharmacies

The feature of the tool is thatphysicians are characterized exclusively from the positive side, while individual patients are prone to criticism of it.

A source: http://zdorovya-spine.ru/preparaty-i-lekarstva/artradol.html

Artradol instructions for use and analogues

Age changes, lack of sufficient mobility, trauma and chronic diseases of internal organs often cause cartilage tissue diseases.

The main functions of joints are violated, there is a degradation of tissues, which leads not only to the limitation of habitual movements, but also to the complete disability of a person.

To restore lost functions help special chondroprotective drugs, one of which is Artradol.

The basic description of the preparation

Arthraldol is a drug whose main active ingredient is chondroitin. This is an analogue of the natural components, of which the cartilage itself consists, which allows the medicine to have the following functions:

  • restore and normalize metabolic processes in the joints;
  • prevent further destruction of compounds;
  • promote the regeneration of cells of cartilaginous tissue.

The effect of the drug on the patient's body does not end there: this chondroprotector reduces, and in some cases completely eliminates inflammatory processes in the tissues of the joint and positively affects the coagulability of the blood, which contributes to the improvement of the internal organs in all of the human body.

Arthreadol medication has two forms of release - an ointment and ampoules with a special powder, from which a solution for intramuscular injection is prepared immediately before use.

The lyophilysian (powder) must be diluted in certain proportions with water for injection or physiological saline.

The basic composition of both forms is the same - chondroitin sodium sulfate, known for its restoring abilities in the soft tissues of the musculoskeletal system.

The total volume of the active ingredient in the drug for external use is 5%. Ointment is used to treat degenerative changes in the joints of the whole body: the upper and lower extremities, the spine, small joints.

Pharmacological features of the agent

Pharmacological action of the drug is wide and varied. Although its main purpose is the regeneration of cartilaginous tissue, it is performed by acting on many metabolic processes of the body, which leads to the normalization of the work of not only musculoskeletal apparatus.

  1. The main reason for the development of inflammation to which the articular cartilage is exposed is a bacterial microflora. Chondroitin is able to restrain its growth, which leads to a reduction in these processes.
  2. To restore the tissue damaged by inflammation help special high-molecular compounds - proteoglycans, which are the main cellular matrix. It is their enhanced synthesis that stimulates the main active substance of the drug. Influencing the metabolic processes, chondroitin restores the exchange of phosphorus and calcium in the body of the patient, additionally acting as a "substitute" for these building materials. Also, it is able to suppress the enzyme, which contributes to the disintegration of cells of the cartilaginous tissue, which helps them to recover independently.
  3. Due to the blocking of the derivative components of the destructive processes, the patient's pains decrease, which facilitates the general state of human health.

All these effects allow Artradol to belong to the class of painkillers, anti-inflammatory and regenerating cartilage tissue preparations.

Artradola injections instantly penetrate into the bloodstream, with external application it takes about 20 minutes to penetrate the active substance into the blood.

But in both cases, the maximum concentration of the active ingredient occurs one hour after the administration of the drug to the patient.

The complete excretion of the constituents of the medicine occurs two days after the last treatment procedure together with the metabolic products in the form of urine. The accumulation of the active ingredient in large quantities by internal organs does not occur.

Indications and contraindications for use

The main group of diseases for which this chronroprotective drug is intended is degenerative changes in the soft tissues of articular joints. It can be both diseases of the limbs, and the ridge of man. They include:

  • osteoarthrosis is a pathology caused by joint trauma, development of inflammatory processes or dysplasia (underdevelopment) of cartilaginous tissue in it. They are used as one of the means of complex treatment in the primary and secondary forms of the development of the disease;
  • Spondylarthrosis is an ailment to which intervertebral discs are exposed. The result of the disease are the changes in the vertebrae itself and the pinching of the nerve endings of the spinal cord;
  • osteochondrosis is a disease of the spine, as a result of which first disks and then vertebrae are destroyed. Effective drug and the violation of depreciation processes in the cartilaginous tissue of the ridge;
  • arthrosis (in the initial stage) - dystrophic changes of non-inflammatory nature. In this case, the joint is destroyed due to aging processes of the body, and not as a result of the development of any concomitant diseases.

The main contraindication to the use of the drug is the individual intolerance of chondroitin or any other auxiliary substances of the drug.

Do not use Artradol in pediatrics, since there are no clinical studies on the transfer of funds by children and adolescents under 15 years.

Contraindicated drug future mothers and women during lactation.

Also, do not prescribe medication to patients suffering:

  • thrombophlebitis;
  • stomach ulcers or duodenal ulcers;
  • tendency to bleeding.

How to apply the medicine

The instructions for the use of the preparation contained in the packaging of each pharmaceutical product attached to Artradol describe in detail the dosage and indications for admission.

If the doctor has prescribed intramuscular injections, the therapy is started with a minimum dosage. It is one milliliter, it is necessary to prick the injections every other day.

If more intensive treatment is required, and provided that the patient tolerates the drug well, the dosage is increased.

For the appearance of unwanted reactions of the body should be observed for at least a week, that is, the dose change should occur no earlier than after three injections and no more than twice.

To raise a powder for injections with a special liquid is necessary immediately before the procedure in the amount necessary for one injection. Therapy is carried out by courses (25-35 procedures), the duration of the break and the need for re-treatment is determined by the treating specialist.

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Ointment Artradol is available in a 30 ml glass container.

A small amount of the drug (not more than one gram) is applied to the area of ​​the body where the affected joint, and massage for several minutes to ensure a more rapid and deep absorption facilities. Such treatment is carried out 2-3 times a day, if necessary - more often. If there are any unpleasant reactions of the body (itching, burning, redness, rashes on the skin), indicating the development of an allergic reaction, therapy is stopped and consulted by a doctor. If necessary, the specialist will reduce the dose or recommend an analogue excluding the allergic component.

To remove the symptoms of allergy recommend the adoption of antihistamines.

Features of the drug

Undesirable reactions of the body in the treatment with arthadol occur in fairly rare cases and are most often due to the excess of the recommended dosage of the drug.

In addition to common reactions of individual intolerance of the drug (skin reactions, swelling of the mucous membranes), changes in the basic clinical parameters of the blood are possible.

Usually this is a decrease in the level of platelets - the substances responsible for the coagulability of the biological fluid. The gluteus muscle can also react, on which the compaction, edema or hematoma occur at the injection site.

The latter reaction does not require the withdrawal of the drug and disappears on its own after a few days.

Particular care should be taken when assigning the chondroprotectors of this group to elderly patients who are prone to diseases of the circulatory system.

Such patients are shown constant monitoring of clinical parameters of blood and parameters of the heart muscle. This is due to the fact that chondroitin liquefies the blood, which ensures its enhanced movement through the veins and arteries.

This can lead to an acceleration of the heart rate, increased blood pressure, exacerbation of thrombophlebitis.

Patients who are suspected of developing a peptic ulcer of the digestive system, colitis or gastric haemorrhage in a history, Treatment with Artradol is also not recommended, in case of acute need it is carried out under strict medical supervision in stationary conditions. Also, with caution and in the presence of strict medical indications, the drug is prescribed for patients with endocrine pathologies (diabetes mellitus type I and II).

For the duration of this medication, it is recommended that you do not take alcohol. If the patient is shown other drugs in which ethyl alcohol is present, they should be taken no earlier than an hour after the injection.

According to clinical studies and the experience of using Artradol in practice, it practically does not cause unpleasant reactions of the body. Also, in the majority of cases, patients showed a positive dynamics of treatment.

If treatment with this drug is impossible or undesirable, the attending physician can replace it with similar drugs.

The most popular of these are Chondroitin, Nimesil, Glucosamine, and hondrolon Hondrogard.

The decision to replace is taken only by a doctor, it's strictly forbidden to do it yourself.

A source: https://TravmaOff.ru/lekarstva/artradol.html

Artradol: instructions for use, reviews

Quite often, a sedentary lifestyle, impaired metabolism, excessive physical activity, Infectious and inflammatory diseases, various traumas lead to such ailments as osteoarthritis and osteochondrosis. In some cases, which happens rarely, people can suffer a lifetime of degenerative-degenerative processes occurring in the joints.

With the above diseases are most often encountered in old age. Nevertheless, similar manifestations are also found in young people. In such a situation, indispensable help will be provided by the medicine "Artradol". Instruction, photos will be presented below.

Composition and form of release

The medicine is presented in the form of a lyophilizate, from which a special solution is used, used intramuscularly.

Another dosage form of "Artradol" is porous white tablets with barely noticeable yellowness.

They are less successful than injection solutions, so it is recommended to give preference to the drug in ampoules.

The active substance of the drug is chondroitin sodium sulfate. One ampoule contains 100 mg. As a rule, in one cardboard bundle there are 10 glass ampoules placed in plastic pallets. The medicine is stored in a dark and dry place at a temperature of less than 20 degrees.

Pass drug "Artradol" (instructions for use as indicated) for three years, after this period is not recommended, because you can only make the situation worse health. The drug is dispensed in pharmacies only if there is an appropriate prescription.

pharmachologic effect

The main component part of the drug present in the proteoglycans of them together with the fibers and is composed by cartilaginous cartilage matrix.

The drug "Artradol" has a chondroprotective action:

  • Neutralizes the activity of enzymes that cause the degradation of articular cartilage.
  • Promotes the synthesis of proteoglycans.
  • Takes part in the phosphoric-calcium metabolism in the cartilaginous tissue, promotes its regeneration.
  • Accelerates metabolic processes occurring in cartilage and subchondral bone.
  • Participates in the construction of chondromucoid - the main substance of cartilaginous tissue.

In addition, "Artradol" has anti-inflammatory, analgesic effect, restores cartilaginous surfaces of joints, participates in the normalization of articular fluid, which improves the mobility of joints and pass pain, prevents the destruction of cartilaginous tissue, which does not lead to the collapse of connective structures.

Chondroitin sulfate is similar to heparin and potentially prevents fibrin thrombus formation in the synovial and subarachnoid microcirculatory bed.

With intramuscular use of "Artradol" the active substance is easily absorbed, after half an hour in the blood its concentration considerably increases, and after a quarter of an hour it is in the synovial liquid.

The maximum concentration of the drug is achieved after the introduction in about an hour, the next two days it will gradually fall. Accumulates the drug directly in the cartilaginous tissue.

In the withdrawal of chondroitin sulfate, the kidneys participate, this occurs within 24 hours. Do not forget that the drug "Artradol" can be dangerous. Instructions on the use of tablets and injections prohibit storage in accessible places for children.

Indications for prescription

As mentioned above, the "Artradol" medication instructions for use recommend for use in degenerative-dystrophic diseases that occur in the joints and spine. These conditions include such pathological changes:

  • Intervertebral osteochondrosis.
  • Primary arthrosis.
  • Osteoarthritis, if the disease occurs with lesion of large joints: knee or femoral.

Contraindications

Of course, we should not ignore the contraindications that "Artradol" has.

Instructions for use include increased sensitivity to the ingredients that make up the drug, and, of course, children's age.

In addition, it is necessary to monitor the coagulability of the blood, if the drug is taken in conjunction with fibrinolytics, anticoagulants and antiaggregants.

Application and dosage

The drug in ampoules is prescribed intramuscularly for 100 mg every other day. "Artradol" (nyxes) instruction for use prescribes to set according to a certain scheme. First, the powder contained in the ampoule must be dissolved in water (1 milliliter).

Dosage can be increased to 200 mg not earlier than on the fourth day, and only if there is a good tolerance of the drug "Artradol".

Instructions for use notes that this drug provides good protection of the cartilage of joints from possible damage.

The course of treatment with the drug - no more than 35 injections. Repeated use of the drug is permissible after six months. The duration of treatment should be determined directly by the treating doctor.

Artradol: instructions for use, reviews, analogues

It is worth mentioning that the drug reviews are mostly positive. At the same time, patients complain about the high cost of the drug. 10 ampoules of "Artradol" cost about 700-850 rubles. The cost will depend on the region and the pharmacy network.

As people note, the use of the drug in a short time reduces pain syndrome, swelling goes away, normal motor function of the joints is restored. Doctors also have a good opinion about this medicine. They say that its continued use contributes to the restoration of cartilaginous tissues.

The composition of "Artradol" is quite simple, so there is no problem with finding drugs of a similar action. Identical properties are possessed by means of "Chondrolon it also includes chondroitin. Before you can independently look for analogues, consult your physician beforehand.

At the same time to search for synonyms it is necessary in rare cases.

Such characteristics as effective reduction of symptoms of the disease, real restoration of tissues made "Artradol" a rather popular drug.

To achieve a recovery effect, several injection courses will be required (effectiveness depends entirely on the stage of the disease and individual indicators).

special instructions

If the drug is used in conjunction with indirect anticoagulants, fibrinolytics or antiplatelet agents, as often as possible it is necessary to monitor the clotting factor. With special care, "Artradol" is prescribed for bleeding, thrombophlebitis.

Finally I would like to note that the medicinal preparation "Artradol the instruction for its application was given in this article, is a standard drug in its composition, but at the same time brings an indispensable benefit organism.

A source: https://www.syl.ru/article/180509/new_artradol-instruktsiya-po-primeneniyu-otzyivyi

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